Sequencing of single and double stranded RNA oligonucleotides by acid hydrolysis and MALDI mass spectrometry

Analytical Chemistry

Volumn 81, Issue 8, 2009, Pages 3173-3179

  Bahr, Ute ^a   Aygün, Hüseyin ^b   Karas, Michael ^a  

^a GOETHE UNIVERSITY   (Germany)

^b BioSpring GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACID HYDROLYSIS; CLEAVAGE EFFICIENCIES; DEGRADATION PRODUCTS; DOUBLE STRANDS; DOUBLE-STRANDED RNAS; FAST METHODS; HIGH RESOLUTIONS; LOCALIZATION AND IDENTIFICATIONS; MALDI-MASS SPECTROMETRIES; MASS DIFFERENCES; METHOXY; NOVO SEQUENCING; ORBITRAP; PHOSPHODIESTER BONDS; STRONG ACIDS;

ACIDS; DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETERS; MASS SPECTROMETRY; OLIGOMERS; OLIGONUCLEOTIDES; PHOTODEGRADATION; POLYMERS; RNA;

NUCLEIC ACIDS;

ACID; DOUBLE STRANDED RNA; PHOSPHODIESTERASE; RIBOSE; SINGLE STRANDED RNA; SMALL INTERFERING RNA;

ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; DEGRADATION; HYDROLYSIS; MASS; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PH; RNA CLEAVAGE; RNA SEQUENCE;

ACIDS; BASE SEQUENCE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; OLIGORIBONUCLEOTIDES; RNA; SEQUENCE ANALYSIS, RNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 65249098989     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac900100x     Document Type: Article

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