The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy

Placenta

Volumn 30, Issue 5, 2009, Pages 398-404

  Naruse, K ^a   Lash, G E ^a   Bulmer, J N ^a   Innes, B A ^a   Otun, H A ^a   Searle, R F ^b   Robson, S C ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Early pregnancy; EVT invasion; Spiral artery remodeling; uNK cells; uPA

Indexed keywords

CASEIN; COLLAGENASE; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROTEINASE; UROKINASE; UROKINASE RECEPTOR;

ARTERY; ARTICLE; BIOPSY; CELL CULTURE; CELL DEGENERATION; CELL INVASION; CELL ISOLATION; CELL LYSATE; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CELL MOTION; CONTROLLED STUDY; DECIDUA; ENZYME ACTIVITY; FEMALE; FIRST TRIMESTER PREGNANCY; GEL; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MIGRATION; MYOMETRIUM; NATURAL KILLER CELL; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PROTEIN SECRETION; STEM CELL; SUPERNATANT; TECHNIQUE; TROPHOBLAST; UTERUS; WESTERN BLOTTING; ZYMOGRAPHY;

BIOPSY; CASEINS; DECIDUA; FEMALE; GESTATIONAL AGE; HUMANS; KILLER CELLS, NATURAL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLASMINOGEN ACTIVATOR INHIBITOR 2; PREGNANCY; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 65049083330     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2009.02.002     Document Type: Article

References (36)

1. Preissner K.T., Kanse S.M., and May A.E. Urokinase receptor: a molecular organizer in cellular communication. Curr Opin Cell Biol 12 (2000) 621-628
2. Vassalli J.D., Sappino A.P., and Belin D. The plasminogen activator/plasmin system. J Clin Invest 88 (1991) 1067-1072
3. Kanse S.M., Kost C., Wilhelm O.G., Andreasen P.A., and Preissner K.T. The urokinase receptor is a major vitronectin-binding protein on endothelial cells. Exp Cell Res 224 (1996) 344-353
4. Bischof P., and Irminger-Finger I. The human cytotrophoblastic cell, a mononuclear chameleon. Int J Biochem Cell Biol 37 (2005) 1-16
5. Pijnenborg R., Vercruysse L., and Hanssens M. The uterine spiral arteries in human pregnancy: facts and controversies. Placenta 27 (2006) 939-958
6. Pijnenborg R., Bland J.M., Robertson W.B., and Brosens I. Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. Placenta 4 (1983) 397-413
7. Lala P.K., and Chakraborty C. Factors regulating trophoblast migration and invasiveness: possible derangements contributing to pre-eclampsia and fetal injury. Placenta 24 (2003) 575-587
8. Lash G.E., Otun H.A., Innes B.A., Bulmer J.N., Searle R.F., and Robson S.C. Low oxygen concentrations inhibit trophoblast cell invasion from early gestation placental explants via alterations in levels of the urokinase plasminogen activator system. Biol Reprod 74 (2006) 403-409
9. Lash G.E., Otun H.A., Innes B.A., Bulmer J.N., Searle R.F., and Robson S.C. Inhibition of trophoblast cell invasion by TGFB1, 2, and 3 is associated with a decrease in active proteases. Biol Reprod 73 (2005) 374-381
10. Al-Atrash G., Shetty S., Idell S., Xue Y., Kitson R.P., Halady P.K.S., et al. IL-2-mediated upregulation of uPA and uPAR in natural killer cells. Biochem Biophys Res Com 292 (2002) 184-189
11. bright natural killer cells in the human early pregnancy decidua. Int Immunol 5 (1993) 559-563
12. Bulmer J.N., Morrison L., Longfellow M., Ritson A., and Pace D. Granulated lymphocytes in human endometrium: histochemical and immunohistochemical studies. Hum Reprod 6 (1991) 791-798
13. Bulmer J.N., and Lash G.E. Human uterine natural killer cells: a reappraisal. Mol Immunol 42 (2005) 511-521
14. Lash G.E., Schiessl B., Kirkley M., Innes B.A., Cooper A., Searle R.F., et al. Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy. J Leukoc Biol 80 (2006) 572-580
15. Robson S.C., Simpson H., Ball E., Lyall F., and Bulmer J.N. Punch biopsy in human placental bed. Am J Obstet Gynecol 187 (2002) 1349-1355
16. Sappino A.P., Madani R., Huarte J., Belin D., Kiss J.Z., Wohlwend A., et al. Extracellular proteolysis in the adult murine brain. J Clin Invest 92 (1993) 679-685
17. Adams E.J., Green J.A., Clark A.H., and Youngson J.H. Comparison of different scoring systems for immunohistochemical staining. J Clin Pathol 52 (1999) 75-77
18. + lymphocytes on killing of natural killer- and lymphokine-activated killer-sensitive targets. Biol Reprod 58 (1998) 982-987
19. Graham C.H., and McCrae K.R. Altered expression of gelatinase and surface-associated plasminogen activator activity by trophoblast cells isolated from placentas of preeclamptic patients. Am J Obstet Gynecol 175 (1996) 555-562
20. Al-Atrash G., Kitson R.P., Sue Y., Mazar A.P., Kim M.H., and Goldfarb R.H. uPA and uPAR contribute to NK cell invasion through the extracellular matrix. Anticancer Res 21 (2001) 1697-1704
21. Gellert G.C., Goldfarb R.H., and Kitson R.P. Physical association of uPAR with the alphaV integrin on the surface of human NK cells. Biochem Biophys Res Commun 315 (2004) 1025-1032
22. Lash G.E., Otun H.A., Innes B.A., Kirkley M., De Oliveira L., Searle R.F., et al. Interferon-γ inhibits extravillous trophoblast cell invasion by a mechanism that involves both changes in apoptosis and protease levels. FASEB J 20 (2006) 2512-2518
23. Multhaupt H.A., Mazar A., Cines D.B., Warhol M.J., and McCrae K.R. Expression of urokinase receptors by human trophoblast. A histochemical and ultrastructural analysis. Lab Invest 71 (1994) 392-400
24. Floridon C., Niesen O., Holund B., Sunde L., Westergaard J.G., Thomsen S.G., et al. Localization and significance of urokinase plasminogen activator and its receptor in placental tissue from intrauterine, ectopic and molar pregnancies. Placenta 20 (1999) 711-721
25. Hu Z.Y., Liu Y.X., Liu K., Byrne S., Ny T., Feng Q., et al. Expression of tissue type and urokinase type plasminogen activators as well as plasminogen activator inhibitor type-1 and type-2 in human and rhesus monkey placenta. J Anat 194 (1999) 183-185
26. Tsatas D., Baker M.S., and Rice G.E. Tissue-specific expression of the relaxed conformation of plasminogen activator inhibitor-2 and low-density lipoprotein receptor-related protein in human term gestational tissues. J Histochem Cytochem 45 (1997) 1593-1602
27. Plaisier M., Koolwijk P., Willems F., Helmerhorst F.M., and van Hinsbergh V.W.M. Pericellular-acting proteases in human first trimester decidua. Mol Hum Reprod 14 (2008) 41-51
28. Ueyama M., Kasatori N., Urayama T., Maemura T., Yao Y., Shiraishi T., et al. Quantitative evaluation of the influence of ovarian steroids on plasminogen activators and inhibitors in human endometrial cells and trophoblasts. Thromb Res 108 (2002) 235-244
29. Bruse C., Guan Y., Carlberg M., Carlstrom K., and Bergqvist A. Basal release of urokinase plasminogen activator, plasminogen activator inhibitor-1, and soluble plasminogen activator receptor from separated and cultured endometriotic and endometrial stromal and epithelial cells. Fertil Steril 83 (2005) 1155-1160
30. Anteby E.Y., Greenfield C., Natanson-Yaron S., Goldman-Wohl D., Hamani Y., Khudyak V., et al. Vascular endothelial growth factor, epidermal growth factor and fibroblast growth factor-4 and -10 stimulate trophoblast plasminogen activator system and metalloproteinase-9. Mol Hum Reprod 10 (2004) 229-235
31. Lash G.E., Otun H.A., Percival K., Innes B.A., Bulmer J.N., Searle R.F., et al. Uterine natural killer cell regulation of trophoblast invasion. Reprod Sci 14 (2007) 258A
32. Hanna J., Goldman-Wohl D., Hamani Y., Avraham I., Greenfield C., Natanson-Yaron S., et al. Decidual NK cell regulate key developmental processes at the human fetal-maternal interface. Nat Med 12 (2006) 1065-1074
33. Hu Y., Dutz J.P., MacCalman C.D., Yong P., Tan R., and von Dadelszen P. Decidual NK cells alter in vitro first trimester extravillous cytotrophoblast migration: a role for IFN-gamma. J Immunol 177 (2006) 8522-8530
34. Craven C.M., Morgan T., and Ward K. Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts. Placenta 19 (1998) 241-252
35. Kam E.P., Gardner L., Loke Y.W., and King A. The role of trophoblast in the physiological change in decidual spiral arteries. Hum Reprod 14 (1999) 2131-2138
36. Naruse K., Lash G.E., Innes B.A., Otun H.A., Oliveira L.G., Searle R.F., et al. Uterine natural killer cells disrupt vascular smooth muscle structure in vitro: A role in spiral artery remodeling?. Placenta 28 (2007) A22