Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency

Journal of Bone and Mineral Metabolism

Volumn 27, Issue 3, 2009, Pages 324-332

  Hara, Kuniko ^a   Akiyama, Yasuhiro ^a  

^a EISAI CO LTD   (Japan)

Author keywords

Ascorbic acid deficiency; Bone quality; Collagen abnormality; Menatetrenone; Rat

Indexed keywords

MENATETRENONE; OSTEOCALCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCORBIC ACID DEFICIENCY; BODY WEIGHT; BONE MASS; BONE METABOLISM; COLLAGEN DISEASE; COLLAGEN METABOLISM; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

AMINO ACIDS; ANIMALS; ASCORBIC ACID DEFICIENCY; BIOMECHANICS; BODY WEIGHT; BONE AND BONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; COLLAGEN TYPE I; FEMUR; ORGAN SIZE; OSTEOCALCIN; OSTEOGENESIS; PEPTIDES; RATS; REGRESSION ANALYSIS; VITAMIN K 2;

EID: 64949101653     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-009-0069-3     Document Type: Article

References (17)

1. NIH Consensus Development Panel 2001 Osteoporosis prevention, diagnosis and therapy JAMA 285 785 795
2. S Cockayne J Adamson S Lanham-New M Shearer S Gilbody DJ Torgerson 2006 Vitamin K and the prevention of fracture. Systemic review and meta-analysis of randomized controlled trials Arch Intern Med 166 1256 1261
3. 2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis J Bone Miner Res 15 515 521
4. J Iwamoto T Takeda S Ichimura 2001 Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of ethidronate J Orthop Sci 6 487 492
5. 2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells J Biol Chem 281 16927 16934
6. S Englard S Seifter 1986 The biochemical functions of ascorbic acid Ann Rev Nutr 6 365 406
7. B Peterkofsky 1991 Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy Am J Clin Nutr 54 1135S 1140S
8. Y Mizushima T Harauchi T Yoshizaki S Makino 1984 A rat mutant unable to synthesize vitamin C Experientia 40 359 361
9. T Kawai M Nishikimi T Ozawa K Yagi 1992 A missense mutation of L-gulono-γ-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid J Biol Chem 267 21973 21976
10. A Togari M Arai S Nakagawa A Bannno M Aoki S Matsumoto 1995 Alteration of bone status with ascorbic acid deficiency in ODS (osteogenic disorder Shionogi) rats Jpn J Pharmacol 68 255 261
11. T Tsunenari M Fukase T Fujita 1991 Bone histomorphometric analysis for the cause of osteopenia in vitamin C-deficient rat (ODS Rat) Calcif Tissue Int 48 18 27
12. Y Sakamoto Y Takano 2002 Morphological influence of ascorbic acid deficiency on endochondral ossification in osteogenic disorder Shionogi rat Anat Rec 268 93 104
13. M Saito K Marumo K Fujii N Ishioka 1997 Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen Anal Biochem 253 26 32
14. S Harada T Matsumoto E Ogata 1991 Role of ascorbic acid in the regulation of proliferation in osteoblasts-like MC3T3-E1 cells J Bone Miner Res 6 903 908
15. S Ishikawa K Iwasaki M Komaki I Ishikawa 2004 Role of ascorbic acid in periodontal ligament cell differentiation J Periodontol 75 709.716
16. A Goto I Tsukamoto 2003 Increase in tartrate-resistant acid phosphatase of bone at the early stage of ascorbic acid deficiency in the ascorbate-requiring osteogenic disorder Shionogi (ODS) rat Calcif Tissue Int 73 180 185
17. 2 (menatetrenone) inhibits bone loss induced by prednisolone partly through enhancement of bone formation in rats Bone 31 575 581