MAP1a associated light chain 3 increases microtubule stability by suppressing microtubule dynamics

Molecular and Cellular Neuroscience

Volumn 41, Issue 1, 2009, Pages 85-93

  Faller, Elliott M ^a   Villeneuve, Tania S ^a   Brown, David L ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

LC1; LC2; LC3; Light chain; MAP1a; Microtubule dynamics; Microtubules; Neuronal microtubule associated proteins; Nocodazole

Indexed keywords

CELL EXTRACT; CELL PROTEIN; LIGHT CHAIN 1; LIGHT CHAIN 2; LIGHT CHAIN 3; MICROTUBULE ASSOCIATED PROTEIN 1; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING ASSAY; CELL GROWTH; CONTROLLED STUDY; DEPOLYMERIZATION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LIGHT CHAIN; MICROTUBULE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CYTOSKELETON; HELA CELLS; HUMANS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NOCODAZOLE; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; TUBULIN; TUBULIN MODULATORS;

EID: 64849107325     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.02.001     Document Type: Article

References (42)

1. Butner K.A., and Kirschner M.W. Tau protein binds to microtubules through a flexible array of distributed weak sites. J. Cell Biol. 115 3 (1991) 717-730
2. Chapin S.J., and Bulinski J.C. Microtubule stabilization by assembly promoting microtubule associating proteins: a repeat performance. J. Cell Biol. 23 (1992) 236-243
3. Chien C.L., Lu K.S., Lin Y.S., Hsieh C.J., and Hirokawa N. The functional cooperation of MAP1A heavy chain and light chain 2 in the binding of microtubules. Exp. Cell Res. 308 (2005) 446-458
4. Downing K.H., and Bulinski J.C. Tubulin and microtubule structure. Curr Opin Cell Biol. 10 (1998) 16-22
5. Evan G.I., Lewis G.K., Ramsay G., and Bishop J.M. Isolation of monoclonal antibodies specific for the human c-myc proto-oncogene product. Mol. Cell Biol. 5 (1985) 3610-3616
6. Falconer M.M., Echeverri C.J., and Brown D.L. Differential sorting of beta-tubulin isotypes into colchicines-stable microtubules during neuronal and muscle differentiation of embryonal carcinoma cells. Cell Motil. Cytoskeleton. 21 (1992) 313-325
7. Faller E., and Brown D. Modulation of microtubule dynamics by the microtubule-associated protein map1a. J. Neurosci. Res. 87 (2009) 1080-1089
8. Halpain S., and Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 7 (2006) 224
9. Hammarback, J.A., 1997. Distinct structural features of the microtubules associated protein 1 family: MAP1A and MAP1B. In Brain microtubule associated proteins. Modifications in Disease. Eds. Avila, J., Brandt, R. and Kosik, K.S. pp3-16. Harwood academic publishers, Canada.
10. Hammarback J.A., Obar R.A., Hughes S.M., and Vallee R.B. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. Neuron 7 (1991) 129-139
11. Hirokawa N. Microtubule organization and dynamics dependent on microtubule-associated proteins. Curr. Opin. Cell Bio. 6 (1994) 74-81
12. Joshi H.C., and Cleveland D.W. Differential utilization of b-tubulin isotypes in differentiating neurites. J.Cell Biol. 109 (1989) 663-673
13. Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., Kominami E., Ohsumi Y., and Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19 (2000) 5720-5728
14. Kochl R., Hu X.W., Chan E.Y., and Tooze S.A. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 7 (2006) 129-145
15. Kouno T., Mizuguchi M., Tanida I., Ueno T., Kanematsu T., Mori Y., Shinoda H., Hirata M., Kominami E., and Kawano K. Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J. Biol. Chem. 280 (2005) 24610-24617
16. Kuznetsov S.A., and Gelfand V.I. 18 kDa microtubule-associated protein: identification as a new light chain (LC3) of microtubule-associated protein 1 (MAP-1). FEBS (Fed. Eur. Biochem. Soc.) Lett. 212 (1987) 145-148
17. Kuznetsov S.A., Rodionov I.V., Nadezhdina E.S., Murphy D.B., and Gelfand V.I. Identification of a 34-kD polypeptide as a light chain of microtubule-associated protein-1 (MAP-1) and its association with a MAP-1 peptide that binds to microtubules. J.Cell Biol. 102 (1986) 1060-1066
18. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
19. Laferriere N.B., MacRae T.H., and Brown D.L. Tubulin synthesis and assembly in differentiating neurons. Biochem. Cell. Biol. 75 (1997) 103-117
20. Langkopf A., Hammarback J.A., Muller R., Vallee R.B., and Garner C.C. Microtubule-associated proteins 1A and LC2. Two proteins encoded in one messenger RNA. J. Biol. Chem. 267 (1992) 16561-16566
21. Ludueña R.F., Banerjee A., and Khan I.A. Tubulin structure and biochemistry. Curr. Opin. Cell Biol. 4 (1992) 53-57
22. Mann S.S., and Hammarback J.A. Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. J. Biol. Chem. 269 (1994) 11492-11497
23. Mann S.S., and Hammarback J.A. Gene localization and developmental expression of light chain 3: a common subunit of microtubule-associated protein 1A(MAP1A) and MAP1B. J. Neurosci. Res. 43 (1996) 535-544
24. Margolis, L., Job, D., 1994. Microtubule stabilization. In Microtubules, eds. Hyams, J.S. and Clive, W.L. Wiley-Liss Inc, NY. pp.221-228.
25. Matus A. Microtubule-associated proteins: Their potential role in determining neuronal morphology. Annu. Rev. Neurosci. 11 (1988) 29-44
26. Mei X., Sweatt A.J., and Hammarback J.A. Regulation of microtubule-associated protein 1B (MAP1B) subunit composition. J. Neurosci. Res. 62 (2000) 56-64
27. Mitchison T., and Kirschner M. Dynamic instability of microtubule growth. Nature 312 (1984) 237-242
28. Müller, R., Kindler, S., Garner, C.C., 1994. The MAP1 family. In Microtubules, eds. Hyamns, J.S. and Clive, W.L. Wiley-Liss Inc., Ny. pp.141-154.
29. Noiges R., Eichinger R., Kutschera W., Fischer I., Nemeth Z., Wiche G., and Propst F. Microtubule-associated protein 1A (MAP1A) and MAP1B: light chains determine distinct functional properties. J. Neurosci. 22 (2002) 2106-2114
30. Oakley, B.R. (1994). g-Tubulin. In: Microtubules (Hyams, J.S. and Lloyd, C.W., eds.). Wiley-Liss, Inc., New York, pp. 33-45.
31. Pedrotti B., and Islam K. MAP1b promotes efficient tubulin polymerization in vitro. FEBS (Fed. Eur. Biochem. Soc.) Lett. 371 (1995) 29-31
32. Pedrotti B., Soffientini A., and Islam K. Sulphonate buffers affect the recovery of microtubule-associated proteins MAP1 and MAP2: evidence that MAP1A promotes microtubule assembly. Cell Motil. Cytoskelet. 25 (1993) 234-242
33. Rusan N.M., Fagerstrom C.J., Yvon A.M., and Wadsworth P. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin. Mol. Biol. Cell 12 (2001) 971-980
34. Schoenfeld T.A., McKerracher L., Obar R., and Vallee R.B. MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. J. Neurosci. 9 (1989) 1712-1730
35. Togel M., Wiche G., and Propst F. Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain. J. Cell Biol. 143 (1998) 695-707
36. Towbin H., Staehlin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76 (1979) 4350-4354
37. Vaillant A., Muller R., Langkopf A., and Brown D.L. Characterization of the microtubule binding domain of MAP1a and its effects on microtubule dynamics. J. Biol. Chem. 273 (1998) 13973-13981
38. Vallee R.B. A taxol dependant procedure for the purification of microtubules and MAPs. J. Cell Biol. 92 (1982) 435-442
39. Vallee R.B., and Davis S.E. Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1(MAP 1). Proc. Natl. Acad. Sci. USA 80 (1983) 1342-1346
40. Wade R.H., and Hyman A.A. Microtubule structure and dynamics. Curr. Opin. Cell Biol. 9 (1997) 12-17
41. Xiang H., and MacRae T.H. Production and utilization of detyrosinated tubulin in developing Artemia larvae: Evidence for a tubulin-reactive carboxypeptidase. Biochem. Cell Biol. 71 (1995) 673-685
42. Zauner W., Kratz J., Staunton J., Feick P., and Wiche G. Identification of two distinct microtubule binding domains on recombinant rat MAP 1B. Eur. J. Cell Biol. 57 (1992) 66-74