Neuropsychological evidence of impaired cognitive empathy in euthymic bipolar disorder

Journal of Neuropsychiatry and Clinical Neurosciences

Volumn 21, Issue 1, 2009, Pages 59-67

  Shamay Tsoory, Simone ^a   Harari, Hagai ^b   Szepsenwol, Ohad ^b   Levkovitz, Yechiel ^b  

^a UNIVERSITY OF HAIFA   (Israel)

^b SHALVATA MENTAL HEALTH CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BIPOLAR DISORDER; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EMPATHY; FEMALE; HUMAN; MALE; NEUROPSYCHOLOGICAL TEST; NEUROPSYCHOLOGY; OUTCOME ASSESSMENT; PREFRONTAL CORTEX; PRIORITY JOURNAL;

EID: 64849085971     PISSN: 08950172     EISSN: None     Source Type: Journal    
DOI: 10.1176/jnp.2009.21.1.59     Document Type: Article

References (38)

1. Altshuler LL, Ventura J, Van Gorp WG, et al: Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects. Biol Psychiatry. 56 2004; 8:560-569
2. Goswami U, Sharma A, Khastigir U, et al: Neuropsychological dysfunction, soft neurological signs and social disability in euthymic patients with bipolar disorder. Br J Psychiatry 2006; 188:366-373
3. Davis MH: Measuring individual differences in empathy: evidence for a multidimensional approach. J Pers Soc Psychol 1980; 44:113-126
4. Davis MH: Empathy: A Social Psychological Approach. Dubuque, Iowa, Wm. C. Brown Communications, 1994
5. Shamay-Tsoory SG, Shur S, Harari H, et al: Neurocognitive basis of impaired empathy in schizophrenia. Neuropsychology 2007; 21:431-438
6. Baron-Cohen S, Wheelwright S, Hill J, et al: The "Reading the Mind in the Eyes" Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry 2001; 42:241-251
7. Premack D, Woodruff G: Does the chimpanzee have a "theoryof- mind"? Behav Brain Sci 1978; 4:515-526
8. Kaland N, Moller-Nielsen A, Callesen K, et al: A new "advanced" test of theory of mind: evidence from children and adolescents with Asperger syndrome. J Child Psychol Psychiatry 2002; 43:517-528
9. Doody GA, Gotz M, Johnstone EC, et al: Theory of mind and psychoses. Psychol Med 28:397, 1998
10. Olley AL, Malhi GS, Bachelor J, et al: Executive functioning and theory of mind in euthymic bipolar disorder. Bipolar Disord 2005; 5:43-52
11. Kerr N, Dunbar RI, Bentall RP: Theory ofmind deficitsinbipolar affective disorder. J Affect Disord 2003; 3:253-259
12. Bora E, Vahip S, Gonul AS, et al: Evidence for theory of mind deficits in euthymic patients with bipolar disorder. Acta Psychiatr Scand 2005; 2:110-116
13. Shamay-Tsoory SG, Aharon-Peretz J: Dissociable prefrontal networks for cognitive and affective theory of mind: a lesion study. Neuropsychologia 2007; 45:3054-3067
14. Shamay-Tsoory SG, Tomer R, Berger BD, et al: Characterization of empathy deficits following prefrontal brain damage: the role of the right ventromedial prefrontal cortex. J Cogn Neurosci 2003; 3:324-337
15. Blumberg HP, Stern E, Martinez D, et al: Increased anterior cingulate and caudate activity in bipolar mania. Biol Psychiatry 2000; 48:1045-1052
16. DeMay MG, Palvic D, Miller BL: Bipolar disorder and the frontal lobes, in The Human Frontal Lobes: Functions and Disorders. Edited by Miller BL, Cummings JL. New York, Guilford Press, 2007, pp 614-620
17. Borkowska A, Rybakowski JK: Neuropsychological frontal lobe tests indicate that bipolar depressed patients are more impaired than unipolar. Bipolar Disord 2001; 2:88-94
18. Vollm BA, Taylor AN, Richardson P, et al: Neuronal correlates of theory of mind and empathy: a functional magnetic resonance imaging study in a nonverbal task. Neuroimage 2006; 1:90-98
19. Baron-Cohen S, O'Riordan M, Stone V, et al: Recognition of faux pas by normally developing children and children with Asperger syndrome or high-functioning autism. J Autism Dev Disord 1999; 29:407-418
20. Ekman P, Friesen WV: Pictures of Facial Affect. Palo Alto, Calif, Consulting Psychologists Press, 1976
21. Baron-Cohen S, Jolliffe T, Mortimore C, et al: Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger syndrome. J Child Psychol Psychiatry 1997; 38:813-822
22. Robbins TW, James M, Owen AM, et al: Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia 1994 5:266-281
23. Rogers RD, Andrews TC, Grasby PM, et al: Contrasting cortical and subcortical activations produced by attentional-set shifting and reversal learning in humans. J Cogn Neurosci 2000; 12:142- 146
24. Kringelbach ML, Rolls ET: Neural correlates of rapid reversal learning in a simple model of human social interaction. NeuroImage 2003; 20:1371-1383
25. Ozonoff S, Cook I, Coon H, et al: Performance on Cambridge neuropsychological test automated battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the collaborative programs of excellence in autism network. J Autism Dev Disord 2004; 34:139-150
26. Owen AM, Doyon J, Petrides M, et al: Planning and spatial working memory: a positron emission tomography study in humans. Eur J Neurosci 1996; 2:353-364
27. Larson ER, Shear PK, Krikorian R, et al: Working memory and inhibitory control among manic and euthymic patients with bipolar disorder. J Int Neuropsychol Soc 2005; 2:163-172
28. Strakowski SM, Delbello MP, Adler CM: The functional neuroanatomy of bipolar disorder: a review of neuroimagingfindings. Mol Psychiatry 2005; 1:105-116
29. Eslinger PJ: Neurological and neuropsychological bases of empathy. Eur Neurol 1998; 39:193-199
30. Rolls ET: The orbitofrontal cortex. Philos Trans R Soc Lond B Biol Sci 1996; 351:1433-1444
31. Taylor CT, Hirshfeld-Becker DR, Ostacher MJ, et al: Anxiety is associated with impulsivity in bipolar disorder. J Anxiety Disord 2008; 22:868-876
32. Murphy FC, Sahakian BJ, Rubinsztein JS, et al: Emotional bias and inhibitory control processes in mania and depression. Psychol Med 1999; 6:1307-1321
33. Chen CH, Lennox B, Jacob R, et al: Explicit and implicit facial affect recognition in manic and depressed states of bipolar disorder: a functional magnetic resonance imaging study. Biol Psychiatry 2006; 1:31-39
34. Green MJ, Cahill CM, Malhi GS: The cognitive and neurophysiological basis of emotion dysregulation in bipolar disorder. J Affect Disord 2007; 103:29-42
35. Gallese V, Goldman A: Mirror neurons and the simulation theory of mind-reading. Trends Cogn Sci 1999; 12:493-501
36. Inoue Y, Tonooka Y, Yamada K, et al: Deficiency of theory of mind in patients with remitted mood disorder. J Affect Disord 2004; 3:403-409
37. Shamay-Tsoory SG: Empathic processing: its cognitive and affective dimensions and neuroanatomical basis, in The Social Neuroscience of Empathy. Edited by Decety J, Ickes W. Cambridge, Mass, MIT Press 2008
38. Sarfati Y, Hardy-Bayle MC, Nadel J, et al: Attribution of mental states to others by schizophrenic patients. Cogn Neuropsychiatry 1997; 2:1-17