-
1
-
-
28844459409
-
Non-alcoholic steatohepatitis: from cell biology to clinical practice
-
Cortez-Pinto H., de Moura M.C., and Day C.P. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol 44 (2006) 197-208
-
(2006)
J Hepatol
, vol.44
, pp. 197-208
-
-
Cortez-Pinto, H.1
de Moura, M.C.2
Day, C.P.3
-
2
-
-
21044438592
-
Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance
-
Ibdah J.A., Perlegas P., Zhao Y., Angdisen J., Borgerink H., Shadoan M.K., et al. Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance. Gastroenterology 128 (2005) 1381-1390
-
(2005)
Gastroenterology
, vol.128
, pp. 1381-1390
-
-
Ibdah, J.A.1
Perlegas, P.2
Zhao, Y.3
Angdisen, J.4
Borgerink, H.5
Shadoan, M.K.6
-
3
-
-
18144444592
-
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis
-
Perez-Carreras M., Del Hoyo P., Martin M.A., Rubio J.C., Martin A., Castellano G., et al. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. Hepatology 38 (2003) 999-1007
-
(2003)
Hepatology
, vol.38
, pp. 999-1007
-
-
Perez-Carreras, M.1
Del Hoyo, P.2
Martin, M.A.3
Rubio, J.C.4
Martin, A.5
Castellano, G.6
-
4
-
-
0034659814
-
Mitochondrial adaptations to obesity-related oxidant stress
-
Yang S., Zhu H., Li Y., Lin H., Gabrielson K., Trush M.A., et al. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 15 (2000) 259-268
-
(2000)
Arch Biochem Biophys
, vol.15
, pp. 259-268
-
-
Yang, S.1
Zhu, H.2
Li, Y.3
Lin, H.4
Gabrielson, K.5
Trush, M.A.6
-
5
-
-
0034019329
-
Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria
-
Hensley K., Kotake Y., Sang H., Pye Q.N., Wallis G.L., Kolker L.M., et al. Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis 21 (2000) 983-989
-
(2000)
Carcinogenesis
, vol.21
, pp. 983-989
-
-
Hensley, K.1
Kotake, Y.2
Sang, H.3
Pye, Q.N.4
Wallis, G.L.5
Kolker, L.M.6
-
6
-
-
18844389970
-
NASH: a mitochondrial disease
-
Pessayre D., and Fromenty B. NASH: a mitochondrial disease. J Hepatol 42 (2005) 928-940
-
(2005)
J Hepatol
, vol.42
, pp. 928-940
-
-
Pessayre, D.1
Fromenty, B.2
-
8
-
-
0031019249
-
Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia
-
Fleury C., Neverova M., Collins S., Raimbault S., Champigny O., Levi-Meyrueis C., et al. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 15 (1997) 269-272
-
(1997)
Nat Genet
, vol.15
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
-
9
-
-
0025369214
-
The proton leak across the mitochondrial inner membrane
-
Brand M.D. The proton leak across the mitochondrial inner membrane. Biochim Biophys Acta 1018 (1990) 128-133
-
(1990)
Biochim Biophys Acta
, vol.1018
, pp. 128-133
-
-
Brand, M.D.1
-
10
-
-
33745601656
-
Mitochondrial UCPs: new insights into regulation and impact
-
Sluse F.E., Jarmuszkiewicz W., Navet R., Douette P., Mathy G., and Sluse-Goffart C.M. Mitochondrial UCPs: new insights into regulation and impact. Biochim Biophys Acta 1757 (2006) 480-485
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 480-485
-
-
Sluse, F.E.1
Jarmuszkiewicz, W.2
Navet, R.3
Douette, P.4
Mathy, G.5
Sluse-Goffart, C.M.6
-
11
-
-
18744428292
-
Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver
-
Larrouy D., Laharrague P., Carrera G., Viguerie-Bascands N., Levi-Meyrueis C., Fleury C., et al. Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver. Biochem Biophys Res Commun 235 (1997) 760-764
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 760-764
-
-
Larrouy, D.1
Laharrague, P.2
Carrera, G.3
Viguerie-Bascands, N.4
Levi-Meyrueis, C.5
Fleury, C.6
-
12
-
-
0036905051
-
Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis
-
Taniguchi E., Harada M., Kawaguchi T., Koga H., Kumemura H., Hanada S., et al. Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis. Liver 22 (2002) 451-458
-
(2002)
Liver
, vol.22
, pp. 451-458
-
-
Taniguchi, E.1
Harada, M.2
Kawaguchi, T.3
Koga, H.4
Kumemura, H.5
Hanada, S.6
-
13
-
-
7244245510
-
Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein
-
Tan M.G., Ooi L.L., Aw S.E., and Hui K.M. Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein. J Biol Chem 279 (2004) 45235-45244
-
(2004)
J Biol Chem
, vol.279
, pp. 45235-45244
-
-
Tan, M.G.1
Ooi, L.L.2
Aw, S.E.3
Hui, K.M.4
-
15
-
-
23644434842
-
Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells
-
MacLellan J.D., Gerrits M.F., Gowing A., Smith P.J., Wheeler M.B., and Harper M.E. Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. Diabetes 54 (2005) 2343-2350
-
(2005)
Diabetes
, vol.54
, pp. 2343-2350
-
-
MacLellan, J.D.1
Gerrits, M.F.2
Gowing, A.3
Smith, P.J.4
Wheeler, M.B.5
Harper, M.E.6
-
16
-
-
2942610474
-
Improved glucose homeostasis in mice overexpressing human UCP3: a role for AMP-kinase?
-
Schrauwen P., Hardie D.G., Roorda B., Clapham J.C., Abuin A., Thomason-Hughes M., et al. Improved glucose homeostasis in mice overexpressing human UCP3: a role for AMP-kinase?. Int J Obes Relat Metab Disord 28 (2004) 824-828
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 824-828
-
-
Schrauwen, P.1
Hardie, D.G.2
Roorda, B.3
Clapham, J.C.4
Abuin, A.5
Thomason-Hughes, M.6
-
17
-
-
21344450979
-
Uncoupling protein-2 and non-alcoholic fatty liver disease
-
Baffy G. Uncoupling protein-2 and non-alcoholic fatty liver disease. Front Biosci 10 (2005) 2082-2096
-
(2005)
Front Biosci
, vol.10
, pp. 2082-2096
-
-
Baffy, G.1
-
18
-
-
0347318052
-
The AMP-activated protein kinase cascade - a unifying system for energy control
-
Carling D. The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem Sci 29 (2004) 18-24
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
19
-
-
42049090589
-
Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice
-
Sheets A.R., Fulop P., Derdak Z., Kassai A., Sabo E., Mark N.M., et al. Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice. Am J Physiol 294 (2008) G1017-G1024
-
(2008)
Am J Physiol
, vol.294
-
-
Sheets, A.R.1
Fulop, P.2
Derdak, Z.3
Kassai, A.4
Sabo, E.5
Mark, N.M.6
-
20
-
-
0033605261
-
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
-
Chavin K., Yang S., Lin H.Z., Chatham J., Chacko V.P., Hoek J.B., et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 274 (1999) 5692-5700
-
(1999)
J Biol Chem
, vol.274
, pp. 5692-5700
-
-
Chavin, K.1
Yang, S.2
Lin, H.Z.3
Chatham, J.4
Chacko, V.P.5
Hoek, J.B.6
-
21
-
-
4544335155
-
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients
-
Ribeiro P.S., Cortez-Pinto H., Sola S., Castro R.E., Ramalho R.M., Baptista A., et al. Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients. Am J Gastroenterol 99 (2004) 1708-1717
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1708-1717
-
-
Ribeiro, P.S.1
Cortez-Pinto, H.2
Sola, S.3
Castro, R.E.4
Ramalho, R.M.5
Baptista, A.6
-
22
-
-
0032898080
-
Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver
-
Rashid A., Wu T.C., Huang C.C., Chen C.H., Lin H.Z., Yang S.Q., et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. Hepatology 29 (1999) 1131-1138
-
(1999)
Hepatology
, vol.29
, pp. 1131-1138
-
-
Rashid, A.1
Wu, T.C.2
Huang, C.C.3
Chen, C.H.4
Lin, H.Z.5
Yang, S.Q.6
-
23
-
-
0036207189
-
Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
-
Baffy G., Zhang C.Y., Glickman J.N., and Lowell B.B. Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. Hepatology 35 (2002) 753-761
-
(2002)
Hepatology
, vol.35
, pp. 753-761
-
-
Baffy, G.1
Zhang, C.Y.2
Glickman, J.N.3
Lowell, B.B.4
-
24
-
-
0032959236
-
Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes
-
Cortez-Pinto H., Lin Z.L., Yang S.Q., Costa S.O., and Diehl A.M. Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. Gastroenterology 116 (1999) 1184-1193
-
(1999)
Gastroenterology
, vol.116
, pp. 1184-1193
-
-
Cortez-Pinto, H.1
Lin, Z.L.2
Yang, S.Q.3
Costa, S.O.4
Diehl, A.M.5
-
25
-
-
0035986608
-
Possible physiological roles of mitochondrial uncoupling proteins - UCPn
-
Jezek P. Possible physiological roles of mitochondrial uncoupling proteins - UCPn. Int J Biochem Cell Biol 34 (2002) 1190-1206
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1190-1206
-
-
Jezek, P.1
-
26
-
-
0033520771
-
Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study
-
Cortez-Pinto H., Chatham J., Chacko V.P., Arnold C., Rashid A., and Diehl A.M. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 282 (1999) 1659-1664
-
(1999)
JAMA
, vol.282
, pp. 1659-1664
-
-
Cortez-Pinto, H.1
Chatham, J.2
Chacko, V.P.3
Arnold, C.4
Rashid, A.5
Diehl, A.M.6
-
27
-
-
43749104043
-
Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion
-
Evans Z.P., Ellett J.D., Schmidt M.G., Schnellmann R.G., and Chavin K.D. Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion. J Biol Chem 283 (2008) 8573-8579
-
(2008)
J Biol Chem
, vol.283
, pp. 8573-8579
-
-
Evans, Z.P.1
Ellett, J.D.2
Schmidt, M.G.3
Schnellmann, R.G.4
Chavin, K.D.5
-
28
-
-
33748918693
-
Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression
-
Fulop P., Derdak Z., Sheets A., Sabo E., Berthiaume E.P., Resnick M.B., et al. Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression. Hepatology 44 (2006) 592-601
-
(2006)
Hepatology
, vol.44
, pp. 592-601
-
-
Fulop, P.1
Derdak, Z.2
Sheets, A.3
Sabo, E.4
Berthiaume, E.P.5
Resnick, M.B.6
-
29
-
-
0009912839
-
Phenotypic abnormalities in macrophages from leptin-deficient, obese mice
-
Lee F.-Y., Li Y., Yang E.K., Yang S.Q., Lin H.Z., Trush M.A., et al. Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. Am J Physiol 276 (1999) C386-C394
-
(1999)
Am J Physiol
, vol.276
-
-
Lee, F.-Y.1
Li, Y.2
Yang, E.K.3
Yang, S.Q.4
Lin, H.Z.5
Trush, M.A.6
-
30
-
-
0012785395
-
Metformin reverses fatty liver disease in obese, leptin-deficient mice
-
Lin H.Z., Yang S.Q., Chuckaree C., Kuhajda F., Ronnet G., and Diehl A.M. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med 6 (2000) 998-1003
-
(2000)
Nat Med
, vol.6
, pp. 998-1003
-
-
Lin, H.Z.1
Yang, S.Q.2
Chuckaree, C.3
Kuhajda, F.4
Ronnet, G.5
Diehl, A.M.6
-
31
-
-
0037309589
-
Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease
-
Li Z., Yang S., Lin H., Huang J., Watkins P.A., Moser A.B., et al. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 37 (2003) 343-350
-
(2003)
Hepatology
, vol.37
, pp. 343-350
-
-
Li, Z.1
Yang, S.2
Lin, H.3
Huang, J.4
Watkins, P.A.5
Moser, A.B.6
-
32
-
-
22844442137
-
Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis
-
Collins P., Jones C., Choudhury S., Damelin L., and Hodgson H. Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis. Liver Int 25 (2005) 880-887
-
(2005)
Liver Int
, vol.25
, pp. 880-887
-
-
Collins, P.1
Jones, C.2
Choudhury, S.3
Damelin, L.4
Hodgson, H.5
-
33
-
-
1442349997
-
Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death
-
Vincent A.M., Olzmann J.A., Brownlee M., Sivitz W.I., and Russell J.W. Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death. Diabetes 53 (2004) 726-734
-
(2004)
Diabetes
, vol.53
, pp. 726-734
-
-
Vincent, A.M.1
Olzmann, J.A.2
Brownlee, M.3
Sivitz, W.I.4
Russell, J.W.5
-
35
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein A.E., Canbay A., Angulo P., Taniai M., Burgart L.J., Lindor K.D., et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 125 (2003) 437-443
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
|