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Volumn 50, Issue 5, 2009, Pages 857-860

Uncoupling proteins and non-alcoholic fatty liver disease

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

EID: 64749116935     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.02.019     Document Type: Editorial
Times cited : (21)

References (35)
  • 1
    • 28844459409 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: from cell biology to clinical practice
    • Cortez-Pinto H., de Moura M.C., and Day C.P. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol 44 (2006) 197-208
    • (2006) J Hepatol , vol.44 , pp. 197-208
    • Cortez-Pinto, H.1    de Moura, M.C.2    Day, C.P.3
  • 2
    • 21044438592 scopus 로고    scopus 로고
    • Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance
    • Ibdah J.A., Perlegas P., Zhao Y., Angdisen J., Borgerink H., Shadoan M.K., et al. Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance. Gastroenterology 128 (2005) 1381-1390
    • (2005) Gastroenterology , vol.128 , pp. 1381-1390
    • Ibdah, J.A.1    Perlegas, P.2    Zhao, Y.3    Angdisen, J.4    Borgerink, H.5    Shadoan, M.K.6
  • 3
    • 18144444592 scopus 로고    scopus 로고
    • Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis
    • Perez-Carreras M., Del Hoyo P., Martin M.A., Rubio J.C., Martin A., Castellano G., et al. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. Hepatology 38 (2003) 999-1007
    • (2003) Hepatology , vol.38 , pp. 999-1007
    • Perez-Carreras, M.1    Del Hoyo, P.2    Martin, M.A.3    Rubio, J.C.4    Martin, A.5    Castellano, G.6
  • 5
    • 0034019329 scopus 로고    scopus 로고
    • Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria
    • Hensley K., Kotake Y., Sang H., Pye Q.N., Wallis G.L., Kolker L.M., et al. Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis 21 (2000) 983-989
    • (2000) Carcinogenesis , vol.21 , pp. 983-989
    • Hensley, K.1    Kotake, Y.2    Sang, H.3    Pye, Q.N.4    Wallis, G.L.5    Kolker, L.M.6
  • 6
    • 18844389970 scopus 로고    scopus 로고
    • NASH: a mitochondrial disease
    • Pessayre D., and Fromenty B. NASH: a mitochondrial disease. J Hepatol 42 (2005) 928-940
    • (2005) J Hepatol , vol.42 , pp. 928-940
    • Pessayre, D.1    Fromenty, B.2
  • 7
    • 39849091969 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and mitochondrial dysfunction
    • Wei Y., Rector R.S., Thyfault J.P., and Ibdah J.A. Nonalcoholic fatty liver disease and mitochondrial dysfunction. World J Gastroenterol 14 (2008) 193-199
    • (2008) World J Gastroenterol , vol.14 , pp. 193-199
    • Wei, Y.1    Rector, R.S.2    Thyfault, J.P.3    Ibdah, J.A.4
  • 9
    • 0025369214 scopus 로고
    • The proton leak across the mitochondrial inner membrane
    • Brand M.D. The proton leak across the mitochondrial inner membrane. Biochim Biophys Acta 1018 (1990) 128-133
    • (1990) Biochim Biophys Acta , vol.1018 , pp. 128-133
    • Brand, M.D.1
  • 12
    • 0036905051 scopus 로고    scopus 로고
    • Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis
    • Taniguchi E., Harada M., Kawaguchi T., Koga H., Kumemura H., Hanada S., et al. Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis. Liver 22 (2002) 451-458
    • (2002) Liver , vol.22 , pp. 451-458
    • Taniguchi, E.1    Harada, M.2    Kawaguchi, T.3    Koga, H.4    Kumemura, H.5    Hanada, S.6
  • 13
    • 7244245510 scopus 로고    scopus 로고
    • Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein
    • Tan M.G., Ooi L.L., Aw S.E., and Hui K.M. Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein. J Biol Chem 279 (2004) 45235-45244
    • (2004) J Biol Chem , vol.279 , pp. 45235-45244
    • Tan, M.G.1    Ooi, L.L.2    Aw, S.E.3    Hui, K.M.4
  • 15
    • 23644434842 scopus 로고    scopus 로고
    • Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells
    • MacLellan J.D., Gerrits M.F., Gowing A., Smith P.J., Wheeler M.B., and Harper M.E. Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. Diabetes 54 (2005) 2343-2350
    • (2005) Diabetes , vol.54 , pp. 2343-2350
    • MacLellan, J.D.1    Gerrits, M.F.2    Gowing, A.3    Smith, P.J.4    Wheeler, M.B.5    Harper, M.E.6
  • 17
    • 21344450979 scopus 로고    scopus 로고
    • Uncoupling protein-2 and non-alcoholic fatty liver disease
    • Baffy G. Uncoupling protein-2 and non-alcoholic fatty liver disease. Front Biosci 10 (2005) 2082-2096
    • (2005) Front Biosci , vol.10 , pp. 2082-2096
    • Baffy, G.1
  • 18
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - a unifying system for energy control
    • Carling D. The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem Sci 29 (2004) 18-24
    • (2004) Trends Biochem Sci , vol.29 , pp. 18-24
    • Carling, D.1
  • 19
    • 42049090589 scopus 로고    scopus 로고
    • Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice
    • Sheets A.R., Fulop P., Derdak Z., Kassai A., Sabo E., Mark N.M., et al. Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice. Am J Physiol 294 (2008) G1017-G1024
    • (2008) Am J Physiol , vol.294
    • Sheets, A.R.1    Fulop, P.2    Derdak, Z.3    Kassai, A.4    Sabo, E.5    Mark, N.M.6
  • 20
    • 0033605261 scopus 로고    scopus 로고
    • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
    • Chavin K., Yang S., Lin H.Z., Chatham J., Chacko V.P., Hoek J.B., et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 274 (1999) 5692-5700
    • (1999) J Biol Chem , vol.274 , pp. 5692-5700
    • Chavin, K.1    Yang, S.2    Lin, H.Z.3    Chatham, J.4    Chacko, V.P.5    Hoek, J.B.6
  • 21
    • 4544335155 scopus 로고    scopus 로고
    • Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients
    • Ribeiro P.S., Cortez-Pinto H., Sola S., Castro R.E., Ramalho R.M., Baptista A., et al. Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients. Am J Gastroenterol 99 (2004) 1708-1717
    • (2004) Am J Gastroenterol , vol.99 , pp. 1708-1717
    • Ribeiro, P.S.1    Cortez-Pinto, H.2    Sola, S.3    Castro, R.E.4    Ramalho, R.M.5    Baptista, A.6
  • 22
    • 0032898080 scopus 로고    scopus 로고
    • Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver
    • Rashid A., Wu T.C., Huang C.C., Chen C.H., Lin H.Z., Yang S.Q., et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. Hepatology 29 (1999) 1131-1138
    • (1999) Hepatology , vol.29 , pp. 1131-1138
    • Rashid, A.1    Wu, T.C.2    Huang, C.C.3    Chen, C.H.4    Lin, H.Z.5    Yang, S.Q.6
  • 23
    • 0036207189 scopus 로고    scopus 로고
    • Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    • Baffy G., Zhang C.Y., Glickman J.N., and Lowell B.B. Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. Hepatology 35 (2002) 753-761
    • (2002) Hepatology , vol.35 , pp. 753-761
    • Baffy, G.1    Zhang, C.Y.2    Glickman, J.N.3    Lowell, B.B.4
  • 24
  • 25
    • 0035986608 scopus 로고    scopus 로고
    • Possible physiological roles of mitochondrial uncoupling proteins - UCPn
    • Jezek P. Possible physiological roles of mitochondrial uncoupling proteins - UCPn. Int J Biochem Cell Biol 34 (2002) 1190-1206
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1190-1206
    • Jezek, P.1
  • 26
    • 0033520771 scopus 로고    scopus 로고
    • Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study
    • Cortez-Pinto H., Chatham J., Chacko V.P., Arnold C., Rashid A., and Diehl A.M. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 282 (1999) 1659-1664
    • (1999) JAMA , vol.282 , pp. 1659-1664
    • Cortez-Pinto, H.1    Chatham, J.2    Chacko, V.P.3    Arnold, C.4    Rashid, A.5    Diehl, A.M.6
  • 27
    • 43749104043 scopus 로고    scopus 로고
    • Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion
    • Evans Z.P., Ellett J.D., Schmidt M.G., Schnellmann R.G., and Chavin K.D. Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion. J Biol Chem 283 (2008) 8573-8579
    • (2008) J Biol Chem , vol.283 , pp. 8573-8579
    • Evans, Z.P.1    Ellett, J.D.2    Schmidt, M.G.3    Schnellmann, R.G.4    Chavin, K.D.5
  • 28
    • 33748918693 scopus 로고    scopus 로고
    • Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression
    • Fulop P., Derdak Z., Sheets A., Sabo E., Berthiaume E.P., Resnick M.B., et al. Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression. Hepatology 44 (2006) 592-601
    • (2006) Hepatology , vol.44 , pp. 592-601
    • Fulop, P.1    Derdak, Z.2    Sheets, A.3    Sabo, E.4    Berthiaume, E.P.5    Resnick, M.B.6
  • 29
    • 0009912839 scopus 로고    scopus 로고
    • Phenotypic abnormalities in macrophages from leptin-deficient, obese mice
    • Lee F.-Y., Li Y., Yang E.K., Yang S.Q., Lin H.Z., Trush M.A., et al. Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. Am J Physiol 276 (1999) C386-C394
    • (1999) Am J Physiol , vol.276
    • Lee, F.-Y.1    Li, Y.2    Yang, E.K.3    Yang, S.Q.4    Lin, H.Z.5    Trush, M.A.6
  • 30
    • 0012785395 scopus 로고    scopus 로고
    • Metformin reverses fatty liver disease in obese, leptin-deficient mice
    • Lin H.Z., Yang S.Q., Chuckaree C., Kuhajda F., Ronnet G., and Diehl A.M. Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med 6 (2000) 998-1003
    • (2000) Nat Med , vol.6 , pp. 998-1003
    • Lin, H.Z.1    Yang, S.Q.2    Chuckaree, C.3    Kuhajda, F.4    Ronnet, G.5    Diehl, A.M.6
  • 31
    • 0037309589 scopus 로고    scopus 로고
    • Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease
    • Li Z., Yang S., Lin H., Huang J., Watkins P.A., Moser A.B., et al. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 37 (2003) 343-350
    • (2003) Hepatology , vol.37 , pp. 343-350
    • Li, Z.1    Yang, S.2    Lin, H.3    Huang, J.4    Watkins, P.A.5    Moser, A.B.6
  • 32
    • 22844442137 scopus 로고    scopus 로고
    • Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis
    • Collins P., Jones C., Choudhury S., Damelin L., and Hodgson H. Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis. Liver Int 25 (2005) 880-887
    • (2005) Liver Int , vol.25 , pp. 880-887
    • Collins, P.1    Jones, C.2    Choudhury, S.3    Damelin, L.4    Hodgson, H.5
  • 33
    • 1442349997 scopus 로고    scopus 로고
    • Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death
    • Vincent A.M., Olzmann J.A., Brownlee M., Sivitz W.I., and Russell J.W. Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death. Diabetes 53 (2004) 726-734
    • (2004) Diabetes , vol.53 , pp. 726-734
    • Vincent, A.M.1    Olzmann, J.A.2    Brownlee, M.3    Sivitz, W.I.4    Russell, J.W.5
  • 35
    • 0042165989 scopus 로고    scopus 로고
    • Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
    • Feldstein A.E., Canbay A., Angulo P., Taniai M., Burgart L.J., Lindor K.D., et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 125 (2003) 437-443
    • (2003) Gastroenterology , vol.125 , pp. 437-443
    • Feldstein, A.E.1    Canbay, A.2    Angulo, P.3    Taniai, M.4    Burgart, L.J.5    Lindor, K.D.6


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