A promising anticancer and antimalarial component from the leaves of Bidens pilosa

Planta Medica

Volumn 75, Issue 1, 2009, Pages 59-61

  Kumari, Priyanka ^a   Misra, Kanak ^a   Sisodia, Brijesh Singh ^a   Faridi, Uzma ^a   Srivastava, Suchita ^a   Luqman, Suiab ^a   Darokar, Mahendra Pandurang ^a   Negi, Arvind Singh ^a   Gupta, Madan Mohan ^a   Singh, Subhash Chandra ^a   Kotesh Kumar, Jonnala ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

Author keywords

Anticancer activity; Antimalarial activity; Asteraceae; Bidens pilosa; Phenyl 1,3,5 heptatriyne

Indexed keywords

ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; ARTEMISININ; BETA CAROTENE; CHLOROQUINE; FRIEDELIN; GLUCOSIDE; HEPTANOIC ACID DERIVATIVE; PACLITAXEL; PHENYL 1,3,5 HEPTATRIYNE; PLANT EXTRACT; STIGMASTEROL; UNCLASSIFIED DRUG; ALKYNE; HERBACEOUS AGENT; PHENYLHEPTATRIYNE; PLANT EXTRACT, BIDENS PILOSA;

ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIDENS PILOSA; CANCER CHEMOTHERAPY; CELL ASSAY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG DETERMINATION; ERYTHROCYTE FRAGILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PLANT LEAF; ANIMAL; BIDENS; CHEMISTRY; DRUG EFFECT; ERYTHROCYTE; ISOLATION AND PURIFICATION; OSMOTIC FRAGILITY; PLASMODIUM FALCIPARUM; TUMOR CELL LINE;

ASTERACEAE; BIDENS PILOSA;

ALKYNES; ANIMALS; ANTIMALARIALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIDENS; CELL LINE, TUMOR; DRUGS, CHINESE HERBAL; ERYTHROCYTES; HUMANS; OSMOTIC FRAGILITY; PLANT LEAVES; PLASMODIUM FALCIPARUM;

EID: 64749104582     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0028-1088362     Document Type: Article

References (16)

1. Brandao MGL, Krettli AU, Soares LSR, Nery CGC, Marinuzzi HC. Antimalarial activity of extracts and fractions from Bidens pilosa and Bidens pecies Asteraceae correlated with the presence of acetylenes and flavonoid compounds. J Ethnopharmacol 1997; 57: 131-138
2. Dimo T, Rakotonirina SV, Tan PV, Azay J, Dongo E, Cros G. Leaf methanol extract of Bidens pilosa prevents and attenuates the hypertension induced by high-fructose diet in Wistar rats. J Ethnopharmacol 2002; 83: 183-191
3. Levin MM, Iasnetsov VS, Sulzhenko AI, Farashchuk NF. Experience in treating alopecia areata with galenicals of Bidens triparta. Sovetskaia Meditsina 1974; 10: 135-136
4. Sashida Y, Ogawa K, Kitada M, Karikome H, Mimaki Y, Shimomura H. New aurone glucosides from Bidens pilosa. Chem Pharm Bull 1991; 39: 709-711
5. Kumar JK, Sinha AK. A new disubstituted acetyl acetone from the leaves of Bidens pilosa Linn. Nat Prod Res 2003; 17: 71-74
6. Wu LW, Chiang YM, Chuang HC, Wang SY, Yang GW, Chen YH. Polyacetylenes function as anti-angiogenic agents. Pharm Res 2004; 21: 2112-2119
7. Hoffmann B, Holzl J. Chalcone glucosides from Bidens pilosa. Phytochemistry 1989; 28: 247-249
8. Deba F, Xuan TD, Yasuda M, Tawata S. Chemical composition and antioxidant, antibacterial and antifungal activities of the essential oils from Bidens piolsa Linn. var. radiata. Food Control 2008; 19: 346-352 (Pubitemid 47571015)
9. Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants and the degenerative diseases of aging. ProcNatl Acad Sci U S A 1993; 90: 7915-7922 (Pubitemid 23260825)
10. Snyder LM, Fortier NL, Trainor J, Jacobes J, Lubin B, Chiu D et al. Effect of hydrogen peroxide exposure on normal human erythrocyte deformability, morphology, surface characteristics and spectrin-hemoglobin crosslinking. J Clin Invest 1985; 76: 1971-1977 (Pubitemid 16196072)
11. Yang HL, Chen SC, Chang NW, Chang JM, Lee ML, Tsai PC et al. Protection from oxidative damage using Bidens pilosa extracts in normal human erythrocytes. Food Chem Toxicol 2006; 44: 1513-1521
12. Sundarajan P, Dey A, Doss AG, Rajappan M, Natarajan S. Studies of anticancer and antipyretic activity of Bidens pilosa whole plant. African Health Sci 2006; 6: 27-30
13. Kviecinski MR, Felipe KB, Schoenfelder T, Wiese LP, Rossi MH, Goncalez E et al. Study of the antitumor potential of Bidens pilosa (Asteraceae) used in Brazilian folk medicine. J Ethnopharmacol 2008; 117: 69-75
14. Luqman S, Rizvi SI. Effect of amiloride on the osmotic fragility and sodium/ potassium adenosine triphosphatases activity of erythrocytes. Asia Pac J Pharmacol 2004; 16: 53-55 (Pubitemid 40125291)
15. Saxena HO, Faridi U, Kumar JK, Luqman S, Darokar MP, Shanker K et al. Synthesis of chalcone derivatives on steroidal framework and their anticancer activities. Steroids 2007; 72: 892-900 (Pubitemid 47422269)
16. Trager W, Jensen JB. Human malaria parasites in continuous culture. Science 1976; 193: 673-675