메뉴 건너뛰기




Volumn 101, Issue 5, 2009, Pages 287-299

Discovery of a new RNA-containing nuclear structure in UVC-induced apoptotic cells by integrated laser electron microscopy

Author keywords

H2AX; Apoptosis marker; Cleaved caspase 3; Correlative microscopy; Electron microscopy; Immunofluorescence; Immunogold; Integrated laser electron microscopy; Light microscopy

Indexed keywords

CASPASE 3; HISTONE H2AX; NUCLEIC ACID; PHOSPHORUS; RNA; BIOLOGICAL MARKER; H2AFX PROTEIN, HUMAN; HISTONE;

EID: 64749101189     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1042/BC20080076     Document Type: Article
Times cited : (33)

References (48)
  • 2
    • 0347356277 scopus 로고    scopus 로고
    • A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation
    • Al-Baker, E.A., Boyle, J., Harry, R. and Kill, I.R. (2004) A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation. Exp. Cell Res. 292, 179-186
    • (2004) Exp. Cell Res , vol.292 , pp. 179-186
    • Al-Baker, E.A.1    Boyle, J.2    Harry, R.3    Kill, I.R.4
  • 3
    • 0025203415 scopus 로고
    • Correlation of blood-brain barrier function and HT7 protein distribution in chick brain circumventricular organs
    • Albrecht, U., Seulberger, H., Schwarz, H. and Risau, W. (1990) Correlation of blood-brain barrier function and HT7 protein distribution in chick brain circumventricular organs. Brain Res. 535, 49-61
    • (1990) Brain Res , vol.535 , pp. 49-61
    • Albrecht, U.1    Seulberger, H.2    Schwarz, H.3    Risau, W.4
  • 6
    • 0014510120 scopus 로고
    • A new staining procedure for electron microscopical cytology
    • Bernhard, W. (1969) A new staining procedure for electron microscopical cytology. J. Ultrastruct. Res. 27, 250-265
    • (1969) J. Ultrastruct. Res , vol.27 , pp. 250-265
    • Bernhard, W.1
  • 7
    • 2942529192 scopus 로고    scopus 로고
    • Nuclear stress bodies: A heterochromatin affair?
    • Biamonti, G. (2004) Nuclear stress bodies: a heterochromatin affair? Nat. Rev. Mol. Cell Biol. 5, 493-498
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 493-498
    • Biamonti, G.1
  • 8
    • 0142120567 scopus 로고    scopus 로고
    • From tissue to cellular ultrastructure: Closing the gap between micro- and nanostructural imaging
    • Biel, S.S., Kawaschinski, K., Wittern, K.-P., Hintze, U. and Wepf, R. (2003) From tissue to cellular ultrastructure: closing the gap between micro- and nanostructural imaging. J. Microsc. 212, 91-99
    • (2003) J. Microsc , vol.212 , pp. 91-99
    • Biel, S.S.1    Kawaschinski, K.2    Wittern, K.-P.3    Hintze, U.4    Wepf, R.5
  • 9
    • 0030920941 scopus 로고    scopus 로고
    • Nuclear ribonucleoprotein-containing structures undergo severe rearrangement during spontaneous thymocyte apoptosis. A morphological study by electron microscopy
    • Biggiogera, M., Bottone, M.G. and Pellicciari, C. (1997) Nuclear ribonucleoprotein-containing structures undergo severe rearrangement during spontaneous thymocyte apoptosis. A morphological study by electron microscopy. Histochem. Cell Biol. 107, 331-336
    • (1997) Histochem. Cell Biol , vol.107 , pp. 331-336
    • Biggiogera, M.1    Bottone, M.G.2    Pellicciari, C.3
  • 10
    • 9444254707 scopus 로고    scopus 로고
    • Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest
    • Biggiogera, M., Bottone, M.G., Scovassi, A.I., Soldani, C., Vecchio, L. and Pellicciari, C. (2004) Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest. Biol. Cell 96, 603-615
    • (2004) Biol. Cell , vol.96 , pp. 603-615
    • Biggiogera, M.1    Bottone, M.G.2    Scovassi, A.I.3    Soldani, C.4    Vecchio, L.5    Pellicciari, C.6
  • 11
    • 0027479655 scopus 로고
    • Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
    • Brown, D.G., Sun, X.-M. and Cohen, G.M. (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268, 3037-3039
    • (1993) J. Biol. Chem , vol.268 , pp. 3037-3039
    • Brown, D.G.1    Sun, X.-M.2    Cohen, G.M.3
  • 14
    • 0035192625 scopus 로고    scopus 로고
    • Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors
    • Denegri, M., Chiodi, I., Corioni, M., Cobianchi, F., Riva, S. and Biamonti, G. (2001) Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors. Mol. Biol. Cell 12, 3502-3514
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3502-3514
    • Denegri, M.1    Chiodi, I.2    Corioni, M.3    Cobianchi, F.4    Riva, S.5    Biamonti, G.6
  • 16
    • 0036154027 scopus 로고    scopus 로고
    • Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells
    • Dunkern, T.R. and Kaina, B. (2002) Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells. Mol. Biol. Cell 13, 348-361
    • (2002) Mol. Biol. Cell , vol.13 , pp. 348-361
    • Dunkern, T.R.1    Kaina, B.2
  • 17
    • 0035921686 scopus 로고    scopus 로고
    • Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation
    • Dunkern, T.R., Fritz, G. and Kaina, B. (2001) Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation. Oncogene 20, 6026-6038
    • (2001) Oncogene , vol.20 , pp. 6026-6038
    • Dunkern, T.R.1    Fritz, G.2    Kaina, B.3
  • 18
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A. and Nagata, S. (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43-50
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 20
    • 0032979579 scopus 로고    scopus 로고
    • Direct visualization of a protein nuclear architecture
    • Hendzel, M.J., Boisvert, F.-M. and Bazett-Jones, D.P. (1999) Direct visualization of a protein nuclear architecture. Mol. Biol. Cell 10, 2051-2062
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2051-2062
    • Hendzel, M.J.1    Boisvert, F.-M.2    Bazett-Jones, D.P.3
  • 21
    • 0035081855 scopus 로고    scopus 로고
    • Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells
    • Horky, M., Wurzer, G., Kotala, V., Anton, M., Vojtesek, B., Vácha, J. and Wesierska-Gadek, J. (2001) Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells. J. Cell Sci. 114, 663-670
    • (2001) J. Cell Sci , vol.114 , pp. 663-670
    • Horky, M.1    Wurzer, G.2    Kotala, V.3    Anton, M.4    Vojtesek, B.5    Vácha, J.6    Wesierska-Gadek, J.7
  • 23
    • 0029068358 scopus 로고
    • Nucleolar segregation as an early marker for DNA damage: An experimental study in rats treated with 4-hydroxyaminoquinoline 1-oxide
    • Imazawa, T., Nishikawa, A., Tada, M., Takahashi, M. and Hayashi, Y. (1995) Nucleolar segregation as an early marker for DNA damage: an experimental study in rats treated with 4-hydroxyaminoquinoline 1-oxide. Virchows Arch. 426, 295-300
    • (1995) Virchows Arch , vol.426 , pp. 295-300
    • Imazawa, T.1    Nishikawa, A.2    Tada, M.3    Takahashi, M.4    Hayashi, Y.5
  • 25
    • 0020054067 scopus 로고
    • Combined light and electron microscope in routine histopathology
    • Jones, S., Chapman, S.K. and Crocker, P.R. (1982) Combined light and electron microscope in routine histopathology. J. Clin. Pathol. 35, 425-429
    • (1982) J. Clin. Pathol , vol.35 , pp. 425-429
    • Jones, S.1    Chapman, S.K.2    Crocker, P.R.3
  • 26
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F., Wyllie, A.H. and Currie, A.R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 27
    • 0029762913 scopus 로고    scopus 로고
    • Improving structural integrity of cryosections for immunogold labeling
    • Liou, W., Geuze, H.J. and Slot, J.W. (1996) Improving structural integrity of cryosections for immunogold labeling. Histochem. Cell Biol. 106, 41-58
    • (1996) Histochem. Cell Biol , vol.106 , pp. 41-58
    • Liou, W.1    Geuze, H.J.2    Slot, J.W.3
  • 28
    • 33745487368 scopus 로고    scopus 로고
    • Cell apoptosis: Requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3
    • Lu, C., Zhu, F., Cho, Y.-Y., Tang, F., Zykova, T., Ma,W.-Y., Bode, A.M. and Dong, Z. (2006) Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3. Mol. Cell 23, 121-132
    • (2006) Mol. Cell , vol.23 , pp. 121-132
    • Lu, C.1    Zhu, F.2    Cho, Y.-Y.3    Tang, F.4    Zykova, T.5    Ma, W.-Y.6    Bode, A.M.7    Dong, Z.8
  • 29
    • 33745607326 scopus 로고    scopus 로고
    • H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks
    • Marti, T.M., Hefner, E., Feeney, L., Natale, V. and Cleaver, J.E. (2006) H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks. Proc. Natl. Acad. Sci. U.S.A. 103, 9891-9896
    • (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 9891-9896
    • Marti, T.M.1    Hefner, E.2    Feeney, L.3    Natale, V.4    Cleaver, J.E.5
  • 30
    • 28244474928 scopus 로고    scopus 로고
    • BRCA1 phosphorylation regulates caspase-3 activation in UV-induced apoptosis
    • Martin, S.A. and Ouchi, T. (2005) BRCA1 phosphorylation regulates caspase-3 activation in UV-induced apoptosis. Cancer Res. 65, 10657-10662
    • (2005) Cancer Res , vol.65 , pp. 10657-10662
    • Martin, S.A.1    Ouchi, T.2
  • 31
    • 5444253157 scopus 로고    scopus 로고
    • A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules
    • Metz, A., Soret, J., Vourc'h, C., Tazi, J. and Jolly, C. (2004) A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules. J. Cell Sci. 117, 4551-4558
    • (2004) J. Cell Sci , vol.117 , pp. 4551-4558
    • Metz, A.1    Soret, J.2    Vourc'h, C.3    Tazi, J.4    Jolly, C.5
  • 32
    • 34250892420 scopus 로고    scopus 로고
    • Array tomography: A new tool for imaging the molecular architecture and ultrastructure of neural circuits
    • Micheva, K.D. and Smith, S.J. (2007) Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits. Neuron 55, 25-36
    • (2007) Neuron , vol.55 , pp. 25-36
    • Micheva, K.D.1    Smith, S.J.2
  • 33
    • 0036027771 scopus 로고    scopus 로고
    • Insights into UV-induced apoptosis: Ultrastructure, trichrome stain and spectral imaging
    • Miller, M.L., Andringa, A., Dixon, K. and Carty, M.P. (2002) Insights into UV-induced apoptosis: ultrastructure, trichrome stain and spectral imaging. Micron 33, 157-166
    • (2002) Micron , vol.33 , pp. 157-166
    • Miller, M.L.1    Andringa, A.2    Dixon, K.3    Carty, M.P.4
  • 34
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer, F., Wilson, J.W., Dive, C., Morris, I.D., Hickman, J.A., Wakeling, A.E., Walker, P.R. and Sikorska, M. (1993) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12, 3679-3684
    • (1993) EMBO J , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8
  • 35
    • 0345073699 scopus 로고    scopus 로고
    • A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
    • O'Driscoll, M., Ruiz-Perez, V.L., Woods, C.G., Jeggo, P.A. and Goodship, J.A. (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat. Genet. 33, 497-501
    • (2003) Nat. Genet , vol.33 , pp. 497-501
    • O'Driscoll, M.1    Ruiz-Perez, V.L.2    Woods, C.G.3    Jeggo, P.A.4    Goodship, J.A.5
  • 36
    • 0036329615 scopus 로고    scopus 로고
    • A novel flat-embedding method to prepare ultrathin cryosections from cultured cells in their in situ orientation
    • Oorschot, V., de Wit, H., Annaert, W.G. and Klumperman, J. (2002) A novel flat-embedding method to prepare ultrathin cryosections from cultured cells in their in situ orientation. J. Histochem. Cytochem. 50, 1067-1080
    • (2002) J. Histochem. Cytochem , vol.50 , pp. 1067-1080
    • Oorschot, V.1    de Wit, H.2    Annaert, W.G.3    Klumperman, J.4
  • 37
    • 0017881451 scopus 로고
    • Individual microtubules viewed by immunofluorescence and electron microscopy in the same PtK2 cell
    • Osborn, M., Webster, R.E. and Weber, K. (1978) Individual microtubules viewed by immunofluorescence and electron microscopy in the same PtK2 cell. J. Cell Biol. 77, R27-R34
    • (1978) J. Cell Biol , vol.77
    • Osborn, M.1    Webster, R.E.2    Weber, K.3
  • 38
    • 0347122970 scopus 로고    scopus 로고
    • Nuclear stress granules: The awakening of a sleeping beauty?
    • Sandqvist, A. and Sistonen, L. (2004) Nuclear stress granules: the awakening of a sleeping beauty? J. Cell Biol. 164, 15-17
    • (2004) J. Cell Biol , vol.164 , pp. 15-17
    • Sandqvist, A.1    Sistonen, L.2
  • 39
    • 35148839574 scopus 로고    scopus 로고
    • Correlative microscopy: Bridging the gap between fluorescence light microscopy and cryo-electron tomography
    • Sartori, A., Gatz, R., Beck, F., Rigort, A., Baumeister, W. and Plitzko, J.M. (2007) Correlative microscopy: bridging the gap between fluorescence light microscopy and cryo-electron tomography. J. Struct. Biol. 160, 135-145
    • (2007) J. Struct. Biol , vol.160 , pp. 135-145
    • Sartori, A.1    Gatz, R.2    Beck, F.3    Rigort, A.4    Baumeister, W.5    Plitzko, J.M.6
  • 40
    • 0019585912 scopus 로고
    • Stabilization of the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition
    • Schliwa, M., van Blerkom, J. and Porter, K.R. (1981) Stabilization of the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition. Proc. Natl. Acad. Sci. U.S.A. 78, 4329-4333
    • (1981) Proc. Natl. Acad. Sci. U.S.A , vol.78 , pp. 4329-4333
    • Schliwa, M.1    van Blerkom, J.2    Porter, K.R.3
  • 41
    • 34548020973 scopus 로고    scopus 로고
    • Correlative light and electron microscopy using immunolabeled resin sections
    • Schwarz, H. and Humbel, B.M. (2007) Correlative light and electron microscopy using immunolabeled resin sections. Methods Mol. Biol. 369, 229-256
    • (2007) Methods Mol. Biol , vol.369 , pp. 229-256
    • Schwarz, H.1    Humbel, B.M.2
  • 42
    • 0036557024 scopus 로고    scopus 로고
    • UV-induced DNA damage and repair: A review
    • Sinha, R.P. and Hader, D.-P. (2002) UV-induced DNA damage and repair: a review. Photochem. Photobiol. Sci. 1, 225-236
    • (2002) Photochem. Photobiol. Sci , vol.1 , pp. 225-236
    • Sinha, R.P.1    Hader, D.-P.2
  • 43
    • 33644645971 scopus 로고    scopus 로고
    • Correlative microscopy of ultrathin cryosections in placental research
    • Takizawa, T. and Robinson, J.M. (2006) Correlative microscopy of ultrathin cryosections in placental research. Methods Mol. Med. 121, 351-369
    • (2006) Methods Mol. Med , vol.121 , pp. 351-369
    • Takizawa, T.1    Robinson, J.M.2
  • 44
    • 0015620349 scopus 로고
    • A technique for ultracryotomy of cell suspensions and tissues
    • Tokuyasu, K.T. (1973) A technique for ultracryotomy of cell suspensions and tissues. J. Cell Biol. 57, 551-565
    • (1973) J. Cell Biol , vol.57 , pp. 551-565
    • Tokuyasu, K.T.1
  • 45
    • 0018148591 scopus 로고
    • A study of positive staining of ultrathin frozen sections
    • Tokuyasu, K.T. (1978) A study of positive staining of ultrathin frozen sections. J. Ultrastruct. Res. 63, 287-307
    • (1978) J. Ultrastruct. Res , vol.63 , pp. 287-307
    • Tokuyasu, K.T.1
  • 46
    • 34548696434 scopus 로고    scopus 로고
    • Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis
    • Toné, S., Sugimoto, K., Tanda, K., Suda, T., Uehira, K., Kanouchi, H., Samejima, K., Minatogawa, Y. and Earnshaw, W.C. (2007) Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp. Cell Res. 313, 3635-3644
    • (2007) Exp. Cell Res , vol.313 , pp. 3635-3644
    • Toné, S.1    Sugimoto, K.2    Tanda, K.3    Suda, T.4    Uehira, K.5    Kanouchi, H.6    Samejima, K.7    Minatogawa, Y.8    Earnshaw, W.C.9
  • 47
    • 0018083534 scopus 로고
    • Visualization of the same PtK2 cytoskeletons by both immunofluorescence and low power electron microscopy
    • Webster, R.E., Osborn, M. and Weber, K. (1978) Visualization of the same PtK2 cytoskeletons by both immunofluorescence and low power electron microscopy. Exp. Cell Res. 117, 47-61
    • (1978) Exp. Cell Res , vol.117 , pp. 47-61
    • Webster, R.E.1    Osborn, M.2    Weber, K.3
  • 48
    • 3042801604 scopus 로고    scopus 로고
    • Morphological features of cell death
    • Ziegler, U. and Groscurth, P. (2004) Morphological features of cell death. News Physiol. Sci. 19, 124-128
    • (2004) News Physiol. Sci , vol.19 , pp. 124-128
    • Ziegler, U.1    Groscurth, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.