Equine laminitis: A journey to the dark side of venous

Veterinary Immunology and Immunopathology

Volumn 129, Issue 3-4, 2009, Pages 164-166

  Robertson, Tom P ^a   Bailey, Simon R ^b   Peroni, John F ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Laminar arteries; Laminar microvasculature; Laminar veins; Laminitis; Metabolic syndrome; Thrombosis; Vascular dysfunction

Indexed keywords

AMINE; CORTICOSTEROID DERIVATIVE;

ANIMAL DISEASE; BLOOD FLOW; DISEASE COURSE; HOOF AND CLAW; HORSE; HORSE DISEASE; LAMINITIS; LEUKOCYTE; METABOLIC SYNDROME X; MICROVASCULATURE; REVIEW; THROMBOCYTE ACTIVATION; THROMBOSIS; VASCULARIZATION; VENOCONSTRICTION; WALNUT;

ANIMALS; FOOT DISEASES; HOOF AND CLAW; HORSE DISEASES; HORSES; INFLAMMATION; OXYGEN CONSUMPTION; VASOCONSTRICTION;

EQUIDAE;

EID: 64749095044     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2008.11.015     Document Type: Review

References (20)

1. Adair H.S., Goble D.O., Schmidhammer J.L., and Shires G.M. Laminar microvascular flow, measured by means of laser Doppler flowmetry, during the prodromal stages of black walnut-induced laminitis in horses. Am. J. Vet. Res. 61 (2000) 862-868
2. Allen D., Clark E.S., Moore J.N., and Prasse K.W. Evaluation of equine digital Starling forces and hemodynamics during early laminitis. Am. J. Vet. Res. 51 (1990) 1930-1934
3. Bailey, S.R., 1998. A study of the vascular effects and factors regulating the concentration of 5-hydroxytryptamine in the equine digital circulation. PhD Thesis. University of London.
4. Black S.J., Lunn D.P., Yin C., Hwang M., Lenz S.D., and Belknap J.K. Leukocyte emigration in the early stages of laminitis. Vet. Immunol. Immunopathol. 109 (2006) 161-166
5. Eades S.C., Stokes A.M., Johnson P.J., LeBlanc C.J., Ganjam V.K., Buff P.R., and Moore R.M. Serial alterations in digital hemodynamics and endothelin-1 immunoreactivity, platelet-neutrophil aggregation, and concentrations of nitric oxide, insulin, and glucose in blood obtained from horses following carbohydrate overload. Am. J. Vet. Res. 68 (2007) 87-94
6. Eades S.C., Stokes A.M., and Moore R.M. Effects of an endothelin receptor antagonist and nitroglycerin on digital vascular function in horses during the prodromal stages of carbohydrate overload-induced laminitis. Am. J. Vet. Res. 67 (2006) 1204-1211
7. Eaton S.A., Allen D., Eades S.C., and Schneider D.A. Digital Starling forces and hemodynamics during early laminitis induced by an aqueous extract of black walnut (Juglans nigra) in horses. Am. J. Vet. Res. 56 (1995) 1338-1344
8. Elliott J., and Bailey S.R. Gastrointestinal derived factors are potential triggers for the development of acute equine laminitis. J. Nutr. 136 (2006) 2103-2107
9. Elliott J., Berhane Y., and Bailey S.R. Effects of monoamines formed in the cecum of horses on equine digital blood vessels and platelets. Am. J. Vet. Res. 64 (2003) 1124-1131
10. Eyre P., Elmes P.J., and Strickland S. Corticosteroid-potentiated vascular responses of the equine digit: a possible pharmacologic basis for laminitis. Am. J. Vet. Res. 40 (1979) 135-138
11. Galey F.D., Twardock A.R., Goetz T.E., Schaeffer D.J., Hall J.O., and Beasley V.R. Gamma scintigraphic analysis of the distribution of perfusion of blood in the equine foot during black walnut (Juglans nigra)-induced laminitis. Am. J. Vet. Res. 51 (1990) 688-695
12. Hood D.M., Wagner I.P., and Brumbaugh G.W. Evaluation of hoof wall surface temperature as an index of digital vascular perfusion during the prodromal and acute phases of carbohydrate-induced laminitis in horses. Am. J. Vet. Res. 62 (2001) 1167-1172
13. Katwa L.C., Johnson P.J., Ganjam V.K., Kreeger J.M., and Messer N.T. Expression of endothelin in equine laminitis. Eq. Vet. J. 31 (1999) 243-247
14. Katz L.M., Marr C.M., and Elliott J. Characterization and comparison of the responses of equine digital arteries and veins to endothelin-1. Am. J. Vet. Res. 64 (2003) 1438-1443
15. Odrowaz-Sypniewska G. Markers of pro-inflammatory and pro-thrombotic state in the diagnosis of metabolic syndrome. Adv. Med. Sci. 52 (2007) 246-250
16. Peroni J.F., Moore J.N., Noschka E., Grafton M.E., Aceves-Avila M., Lewis S.J., and Robertson T.P. Predisposition for venoconstriction in the equine laminar dermis: implications in equine laminitis. J. Appl. Physiol. 100 (2006) 759-763
17. Steiger R.R., Belknap J.K., Fontaine G.L., Rodgerson D.H., Emory A.J., and Kroll D.L. Expression of vasoactive and pro-inflammatory mediators by equine digital vessel endothelial cells. J. Vet. Int. Med. 13 (1999) 283 (Abstract)
18. Weiss D.J., Evanson O.A., McClenahan D., Fagliari J.J., and Jenkins K. Evaluation of platelet activation and platelet-neutrophil aggregates in ponies with alimentary laminitis. Am. J. Vet. Res. 58 (1997) 1376-1380
19. Weiss D.J., Monreal L., Angles A.M., and Monasterio J. Evaluation of thrombin-antithrombin complexes and fibrin fragment D in carbohydrate-induced acute laminitis. Res. Vet. Sci. 61 (1996) 157-159
20. Weiss D.J., Trent A.M., and Johnston G. Prothrombotic events in the prodromal stages of acute laminitis in horses. Am. J. Vet. Res. 56 (1995) 986-991