The mechanism of transcriptional regulation of P450 aromatase gene by Foxl2 in Japanese flounder (Paralichthys olivaceus)

Cybium

Volumn 32, Issue 2 SUPPL., 2008, Pages 74-76

  Yamaguchi, Toshiya ^a   Kitano, Takeshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Cyp19; Foxl2; Japanese flounder; P450 aromatase; Temperature dependent sex determination

Indexed keywords

PARALICHTHYS OLIVACEUS; PLEURONECTOIDEI; TELEOSTEI; VERTEBRATA;

EID: 64649102094     PISSN: 03990974     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (4)

1. KAUFMANN E. & W. KNOCHEL, 1996. - Five years on the wings of fork head. Mech. Dev., 57: 3-20.
2. KITANO T., TAKAMUNE K., KOBAYASHI T., NAGAHAMA Y. & S. ABE, 1999. - Suppression of P450 aromatase gene expression in sex-reversed males produced by rearing genetically female larvae at a high water temperature during a period of sex differentiation in the Japanese flounder (Paralichthys olivaceus). J. Mol. Endocrinol., 23: 167-176.
3. KITANO T., TAKAMUNE K., NAGAHAMA Y. & S. ABE, 2000. - Aromatase inhibitor and 17α-methyltestosterone cause sexreversal from genetical females to phenotypic males and suppression of P450 aromatase gene expression in Japanese flounder (Paralichthys olivaceus). Mol. Reprod. Dev., 56: 1-5.
4. WANG D., KOBAYASHI T., ZHOU L., PAUL-PRASANTH B., IJIRI S., SAKAI F, OKUBO K., MOROHASHI K. & Y. NAGAHAMA, 2007. -foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with Ad4BP/SF-1. Mol. Endocrinol., 21: 712-725.