Comparison of efficacy of intrathecal morphine 100μg and 200μg for postoperative pain relief in patients undergoing lower abdominal and lower limb surgeries

Journal of Anaesthesiology Clinical Pharmacology

Volumn 25, Issue 1, 2009, Pages 63-65

  Kamath, Shaila S ^a   Hosagoudar, Pradeep ^a   Ambareesha, ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Bupivacaine; Intrathecal morphine; Lower abdominal and lower limb surgeries; Post operative analgesia; Spinal anaesthesia

Indexed keywords

BUPIVACAINE; MORPHINE; ONDANSETRON; PLACEBO; TRAMADOL;

ABDOMINAL SURGERY; ADULT; AGED; ARTICLE; BLOOD PRESSURE MONITORING; BRADYCARDIA; BREATHING RATE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ELECTROCARDIOGRAPHY MONITORING; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; PAIN ASSESSMENT; PATIENT MONITORING; POSTOPERATIVE ANALGESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRURITUS; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SEDATION; SIDE EFFECT; URINE RETENTION; VOMITING;

EID: 64649089393     PISSN: 09709185     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. T.L.Yaksh, T.M.Jessell, R.Gamse: Intrathecal morphine inhibits substance-P release from mammalian spinal cord in vivo. Nature1980; 286: 155-157.
2. Behar.M, Olshwang.D, Magora.F, Davidson.J.T: Epidural morphine in treatment of pain. Lancet 1979; 1: 527.
3. Wang J.K, Nauss L.A, Thomas.J.E, Cousins.M.J: Spinal narcotics & respiratory depression. Anaesthesiology 1979; 50: 149-51.
4. Robert.K.Stoelting. Pharmacology and Physiology in Anaesthetic Practice. Third edition. Philadelphia: Lippincott - Raven, 1999, 77-113.
5. Edward.T.Mathews, Leon.D.Abrams: Intrathecal morphine in Open Heart Surgery. Lancet 1980; ii: 543.
6. Davis.I: Intrathecal morphine in aortic aneurysm surgery. Anaesthesia 1987: 42(5); 491-7.
7. Jacobson, Chabal.C, Mariano. A, Chaney.E: The combination of intrathecal morphine & PCA provides excellent postoperative analgesia. Anaesthesia Analgesia 1991; 72: S123.
8. P.J.Cole, D.A.Craske, R.G.Wheatley: Efficacy and respiratory effects of low-dose spinal morphine for postoperative analgesia following knee arthroplasty. British Journal of Anaesthesia 2000; 85(2): 233-237.
9. Bailey.P.L, Rhondeau.S, Schafer.P.G, Lu.J.K, Timmins.B.S, Foster.W, Pace.N.L, Stanley.T.H: Dose-response pharmacology of intrathecal morphine in human volunteers. Anaesthesiology 1993; 79(1): 49-59.
10. Yamaguchi. H, Watanabe.S, Motokawa.K, Ishizawa. Y: Intrathecal morphine dose response data for pain relief after cholecystectomy. Anaesthesia Analgesia 1990; 70:168-171.
11. Slappendel. R, Weber. E.W, Dirksen. R, Gielen. M.J, van Limbeek. J: Optimization of the dose of intrathecal morphine in total hip surgery; a dose-finding study. Anaesthesia Analgesia 1999; 88(4): 822-6.
12. Samii.K, Chauvin.M, Viars.P: Postoperative spinal analgesia with morphine. British Journal of Anaesthesia 1981; 53: 817-820.