Neurotoxic effects of subacute exposure of dichlorvos and methyl parathion at sublethal dosages in rats

Pesticide Biochemistry and Physiology

Volumn 94, Issue 1, 2009, Pages 1-4

  Celik, Ismail ^a   Isik, Ismail ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Acetylcholinesterase; Butyrylcholinesterase; Dichlorvos; Methyl parathion; Neurotoxic; Rat; Subacute; Sublethal

Indexed keywords

RATTUS;

EID: 64649088897     PISSN: 00483575     EISSN: 10959939     Source Type: Journal    
DOI: 10.1016/j.pestbp.2009.02.003     Document Type: Article

References (28)

1. Empster J.P. Effect of organochlorine insecticides on animal populations. In: Moriarty F. (Ed). Organo Chlorine Insecticides; Persistent Organic Pollutants (1975), Academic Press, London 331
2. Das B.K., and Mukherjee S.C. Chronic toxic effects of quinalphos on some biochemical parameters in Labeo rohita (Ham.). Toxicol. Lett. 114 (2000) 11
3. Allderdice P.W., Garner H.A.R., Galutira D., Lockridge O., LaDu B.N., and McAlpines J. The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site. Genomics 11 (1991) 452-454
4. Quin D.M. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states. Chem. Rev. 87 (1987) 955-979
5. Raveh L., Grauver E., Grunwald J., Cohen E., and Ashani Y. The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase. Toxicol. Appl. Pharm. 145 (1997) 43-53
6. Ecobichon D.J. Toxic effects of pesticides. In: Klaassen C.D. (Ed). Casarett and Doull's Toxicology. sixth ed. (1996), McGraw-Hill 763-810
7. Dasgupta J., Gupta J., Data A.S., and Sengupta D. Effect of malathion on antioxidant defence system in human fetus an in vitro study. Indian J. Exp. Biol. 30 (1992) 352
8. Bagchi D., Bagchi M., Hassoun E.A., and Stohs S.J. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 104 (1995) 129
9. Gultekin F., Ozturk M., and Akdogan M. The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Arch. Toxicol. 74 (2000) 533
10. Yarsan E., and Cakir O. Effects of dichlorvos on lipid peroxidation in mice on subacute and subchronic periods. Pestic. Biochem. Physiol. 86 (2006) 106-109
11. Roberson E.L., and Nolan M.P. External parasite control. In: Booth N.H., and McDonald L.E. (Eds). Veterinary Pharmacology and Therapeutics. sixth ed. (1988), Iowa State University Press, Ames 892-925
12. Thienes C.H., and Haley T.J. Clinical Toxicology. fifth ed. (1972), Lea and Febiger, Philadelphia, USA
13. Campbell P.I., and Ofurum O.O. Serum and liver enzyme changes in rats after short term exposure to dichlorvos. Comp. Biochem. Physiol. C 83 (1986) 443-446
14. Hasan M., and Ali S.F. Organophosphate pesticide dichlorvos-induced increase in the rate of lipid peroxidation in the different regions of the rat brain: supporting ultra-structural findings. Neurotoxicology 2 (1980) 43-52
15. Celik I., and Suzek H. Effects of subacute exposure of dichlorvos at sublethal dosages on erythrocyte and tissue antioxidant defense systems and lipid peroxidation in rats. Food Chem. Toxicol. 46 (2008) 2796-2801
16. Nehez M., Toth C., and Desi I. The effect of dimethoate, dichlorvos, and parathion-methyl on bone marrow cell chromosomes of rats in subchronic experiments in vivo. Ecotoxicol. Environ. Saf. 29 (1994) 365-371
17. Vijayaraghavan M., and Nagarajan B. Mutagenic potential of acute exposure to organophosphorus and organochlorine compounds. Mutat. Res. 321 (1994) 103-111
18. Bartoli S., Bonora B., Colacci A., Niero A., and Grilli S. DNA damaging activity of methyl parathion. Res. Commun. Chem. Pathol. Pharmacol. 71 (1991) 209-218
19. Grover I.S., and Malhi P.K. Genotoxic effects of some organophosphorus pesticides. I. Induction of micronuclei in bone marrow cells in rat. Mutat. Res. 155 (1985) 131-134
20. Celik I., and Suzek H. The hematological effects of methyl parathion in rats. J. Hazard Mater. 153 (2008) 1117-1121
21. Celik I., and Suzek H. Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats. Food Chem. Toxicol. 46 (2008) 2796-2801
22. Mathew G., Vijayalaxmi K.K., and Abdul Rahiman M. Methyl parathion-induced sperm shape abnormalities in mouse. Mutat. Res. 280 (1992) 169-173
23. Narayana K., Prashanthi N., Nayanatara A., Kumar H.H.C., Abhilash K., and Bairy K.L. Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rats sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis. Mutat. Res. 588 (2005) 28-34
24. Ellman G.L., Courtney K.D., Andres Jr.V., and Featherstone R.M. A new and rapid colorimetric determination of acethylcholinesterase activity. Biochem. Pharmacol. 7 (1961) 88-95
25. Das B.K., and Mukherjee S.C. Chronic toxic effects of quinalphos on some biochemical parameters in Labeo rohita (Ham.). Toxicol. Lett. 114 (2000) 11-18
26. Szabo A., and Nemcsok J. The effect of pesticides on carp (Cyprinus carpio). Acetylcholinesterase and its biochemical characterization. Ecotoxicol. Environ. Saf. 23 (1992) 39-45
27. Julka D., Pal R., and Gill K.D. Neurotoxicity of dichlorvos: effect on antioxidant defense system in the rat central nervous system. Exp. Mol. Pathol. 56 (1992) 144-152
28. Hai D.Q., Varga SI., and Matkovics B. Organophosphate effects on antioxidant system of carp (Cyprinus carpio) and catfish (Lctalurus nebulosus). Comp. Biochem. Physiol. 117C (1997) 83-88