Selection and analysis of HIV-1 integrase strand transfer inhibitor resistant mutant viruses

Methods

Volumn 47, Issue 4, 2009, Pages 277-282

  Witmer, Marc ^a   Danovich, Robert ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

HIV; Inhibitor; InSTI; Integrase; Raltegravir; Replication capacity; Resistance; Selection

Indexed keywords

DIKETOACID; INTEGRASE INHIBITOR; N (4 FLUOROBENZYL) 8 HYDROXY 5 (TETRAHYDRO 2H 1,2 THIAZIN 2 YL) 1,6 NAPHTHYRIDINE 7 CARBOXAMIDE S,S DIOXIDE; NAPHTYRIDINERBOXAMIDE DERIVATIVE; PYRIMIDINECARBOXAMIDE; UNCLASSIFIED DRUG; INTEGRASE; NAPHTHYRIDINE DERIVATIVE; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIBIOTIC RESISTANCE; ARTICLE; CELL CULTURE; DRUG STRUCTURE; GENE MUTATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC CODE; GENOTYPE; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; MOLECULAR CLONING; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; VIRUS REPLICATION; ANTIVIRAL RESISTANCE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; GENETICS; HELA CELL LINE; HUMAN; MUTATION; VIRUS DNA CELL DNA INTERACTION;

CELLS, CULTURED; DRUG RESISTANCE, VIRAL; HELA CELLS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; MUTATION; NAPHTHYRIDINES; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 64649083538     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2009.02.025     Document Type: Article

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