Hyperproliferation in nasal polyposis tissues is not associated with somatic genomic instability

Journal of Otolaryngology - Head and Neck Surgery

Volumn 37, Issue 4, 2008, Pages 510-514

  Corradini, Carlo ^a   Gullotta, Francesca ^b   Ciacci, Silvia ^b   Palmieri, Giampiero ^b   Salehi, Leila Baghernajad ^b   De Corso, Eugenio ^a   Novelli, Giuseppe ^b   Gambardella, Stefano ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Array comparative genome hybridization; Chromosomal aberration; Nasal polyposis

Indexed keywords

DNA; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67;

ADULT; ANTIGEN EXPRESSION; ARTICLE; ARTIFICIAL CHROMOSOME; BACTERIAL ARTIFICIAL CHROMOSOME; CELL PROLIFERATION; CELL STRUCTURE; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CLINICAL FEATURE; DATA ANALYSIS; DISEASE MARKER; DNA HYBRIDIZATION; EPITHELIUM CELL; FEMALE; GENOMIC INSTABILITY; HUMAN; MALE; MOLECULAR CLONING; NOSE MUCOSA; NOSE POLYP; PATHOGENESIS; PRIORITY JOURNAL; SOMATIC CELL; TISSUE;

ADULT; CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GENOMIC INSTABILITY; HUMANS; HYPERPLASIA; KI-67 ANTIGEN; MALE; MIDDLE AGED; NASAL POLYPS;

EID: 64549153627     PISSN: 19160216     EISSN: None     Source Type: Journal    
DOI: 10.2310/7070.2008.0097     Document Type: Article

References (15)

1. Perkins JA, Blakeslee DB, Andrade P. Nasal polyps: a manifestation of allergy? Otolaryngol Head Neck Surg 1989;101:641-5.
2. Henriksson G, Westrin KM, Karpati F, et al. Nasal polyps in cystic fibrosis: clinical endoscopic study with nasal lavage fluid analysis. Chest 2002;121:40-7.
3. Bernstein JM, Gorfien J, Noble B, et al. Nasal polyposis: immunohistochemistry and bioelectrical findings (a hypothesis for the development of nasal polyps). J Allergy Clin Immunol 1997; 99:165-75.
4. Vissers LE, de Vries BB, Osoegawa K, et al. Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities. Am J Hum Genet 2003;73:1261-70.
5. Shaw-Smith C, Redon R, Rickman L, et al. Microarray-based comparative genomic hybridisation (array-CGH) detects submi-croscopic chromosomal deletions and duplications in patients with learning disability/mental retardation and dysmorphic features. J Med Genet 2004;41:241-8.
6. Hui AB, Lo KW, Yin XL, et al. Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridisation. Lab Invest 2001;81: 717-23.
7. Bejjani BA, Theisen AP, Ballif BC, et al. Array-based comparative genomic hybridization in clinical diagnosis. Expert Rev Mol Diagn 2005;5:421-9.
8. Yu W, Ballif BC, Kashork CD, et al. Development of a comparative genomic hybridization microarray and demonstration of its utility with 25 well-characterized 1p36 deletions. Hum Mol Genet 2003; 12:2145-52.
9. Wessendorf S, Fritz B, Wrobel G, et al. Automated screening for genomic imbalances using matrix-based comparative genomic hybridisation. Lab Invest 2002;82:47-60.
10. Vissers LE, de Vries BB, Osoegawa K, et al. Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities. Am J Hum Genet 2003;73:1261-70.
11. Coste A, Rateau JG, Roudot-Thoraval F, et al. Increased epithelial cell proliferation in nasal polyps. Arch Otolaryngol Head Neck Surg 1996;122:432-6.
12. Speleman F, De Potter C, Van Roy N, et al. Multiple polysomies in nasal polyps in children. Cancer Genet Cytogenet 1996;90: 86-7.
13. Vanni R, Medda C, Marras S, et al. Numerical chromosome changes in a nasal polyp. Genes Chromosomes Cancer 1994;10:203-6.
14. Matteucci C, Galieni P, Leoncini L, et al. Typical genomic imbalances in primary MALT lymphoma of the orbit. J Pathol 2003;200:656-60.
15. Obermann EC, Junker K, Stoehr R, et al. Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH, and FISH analyses. J Pathol 2003;199:50-7.