FE65 binds teashirt, inhibiting expression of the primate-specific caspase-4

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Kajiwara, Yuji ^a   Akram, Afia ^a   Katsel, Pavel ^a   Haroutunian, Vahram ^a   Schmeidler, James ^a   Beecham, Gary ^b   Haines, Jonathan L ^c   Pericak Vance, Magaret A ^b   Buxbaum, Joseph D ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 4; HISTONE DEACETYLASE; PROTEIN FE65; REPRESSOR PROTEIN; TEASHIRT PROTEIN 1; TEASHIRT PROTEIN 3; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; APBB1 PROTEIN, HUMAN; CASP4 PROTEIN, HUMAN; INITIATOR CASPASE; NERVE PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AGED; ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; AUTOPSY; CASE CONTROL STUDY; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; COGNITIVE DEFECT; COHORT ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE IDENTIFICATION; GENE SILENCING; GENE TARGETING; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIMATE; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TWO HYBRID SYSTEM; YEAST; ANIMAL; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION;

MURINAE; PRIMATES;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CASPASES, INITIATOR; CHROMATIN IMMUNOPRECIPITATION; GENE SILENCING; HISTONE DEACETYLASES; HUMANS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PRIMATES; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 64549152034     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005071     Document Type: Article

References (55)

1. Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, et al. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736.
2. Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, et al. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704-706.
3. Palmert MR, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, et al. (1988) Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease. Science 241: 1080-1084.
4. Reinhard C, Hebert SS, De Strooper B (2005) The amyloid-beta precursor protein: integrating structure with biological function. Embo J.
5. Cao X, Sudhof TC (2001) A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293: 115-120.
6. Duilio A, Zambrano N, Mogavero AR, Ammendola R, Cimino F, et al. (1991) A rat brain mRNA encoding a transcriptional activator homologous to the DNA binding domain of retroviral integrases. Nucleic Acids Res 19: 5269-5274.
7. Fiore F, Zambrano N, Minopoli G, Donini V, Duilio A, et al. (1995) The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein. J Biol Chem 270: 30853-30856.
8. Zambrano N, Buxbaum JD, Minopoli G, Fiore F, De Candia P, et al. (1997) Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins. J Biol Chem 272: 6399-6405.
9. Sabo SL, Lanier LM, Ikin AF, Khorkova O, Sahasrabudhe S, et al. (1999) Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein. J Biol Chem 274: 7952-7957.
10. Cao X, Sudhof TC (2004) Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation. J Biol Chem 279: 24601-24611.
11. Telese F, Bruni P, Donizetti A, Gianni D, D'Ambrosio C, et al. (2005) Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep 6: 77-82.
12. Hass MR, Yankner BA (2005) A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J Biol Chem 280: 36895-36904.
13. Zambrano N, Minopoli G, de Candia P, Russo T (1998) The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1. J Biol Chem 273: 20128-20133.
14. Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, et al. (2003) Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J Biol Chem 278: 49448-49458.
15. Caubit X, Core N, Boned A, Kerridge S, Djabali M, et al. (2000) Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech Dev 91: 445-448.
16. Caubit X, Tiveron MC, Cremer H, Fasano L (2005) Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain. J Comp Neurol 486: 76-88.
17. Forman-Kay JD, Pawson T (1999) Diversity in protein recognition by PTB domains. Curr Opin Struct Biol 9: 690-695.
18. Ebinu JO, Yankner BA (2002) A RIP tide in neuronal signal transduction. Neuron 34: 499-502.
19. Seo SB, McNamara P, Heo S, Turner A, Lane WS, et al. (2001) Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 104: 119-130.
20. Dokmanovic M, Marks PA (2005) Prospects: histone deacetylase inhibitors. J Cell Biochem 96: 293-304.
21. Johnstone RW (2002) Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat Rev Drug Discov 1: 287-299.
22. Bruni P, Minopoli G, Brancaccio T, Napolitano M, Faraonio R, et al. (2002) Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression. J Biol Chem 277: 35481-35488.
23. Gallet A, Erkner A, Charroux B, Fasano L, Kerridge S (1998) Trunk-specific modulation of wingless signalling in Drosophila by teashirt binding to armadillo. Curr Biol 8: 893-902.
24. Gallet A, Angelats C, Kerridge S, Therond PP (2000) Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila. Development 127: 5509-5522.
25. Alexandre E, Graba Y, Fasano L, Gallet A, Perrin L, et al. (1996) The Drosophila teashirt homeotic protein is a DNA-binding protein and modulo, a HOM-C regulated modifier of variegation, is a likely candidate for being a direct target gene. Mech Dev 59: 191-204.
26. Taghli-Lamallem O, Gallet A, Leroy F, Malapert P, Vola C, et al. (2007) Direct interaction between Teashirt and Sex combs reduced proteins, via Tsh's acidic domain, is essential for specifying the identity of the prothorax in Drosophila. Dev Biol 307: 142-151.
27. Waltzer L, Vandel L, Bienz M (2001) Teashirt is required for transcriptional repression mediated by high Wingless levels. Embo J 20: 137-145.
28. Manfroid I, Caubit X, Kerridge S, Fasano L (2004) Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene. Development 131: 1065-1073.
29. Yang Z, Cool BH, Martin GM, Hu Q (2006) A dominant role for FE65 (APBB1) in nuclear signaling. J Biol Chem 281: 4207-4214.
30. Gaughan L, Logan IR, Cook S, Neal DE, Robson CN (2002) Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor. J Biol Chem 277: 25904-25913.
31. Lee HJ, Chun M, Kandror KV (2001) Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling. J Biol Chem 276: 16597-16600.
32. Xiao H, Chung J, Kao HY, Yang YC (2003) Tip60 is a co-repressor for STAT3. J Biol Chem 278: 11197-11204.
33. Eichenbaum H, Yonelinas AP, Ranganath C (2007) The medial temporal lobe and recognition memory. Annu Rev Neurosci 30: 123-152.
34. Kordower JH, Chu Y, Stebbins GT, DeKosky ST, Cochran EJ, et al. (2001) Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Ann Neurol 49: 202-213.
35. Delacourte A, David JP, Sergeant N, Buee L, Wattez A, et al. (1999) The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease. Neurology 52: 1158-1165.
36. Pompl PN, Yemul S, Xiang Z, Ho L, Haroutunian V, et al. (2003) Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease. Arch Neurol 60: 369-376.
37. Martinon F, Tschopp J (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117: 561-574.
38. Lin XY, Choi MS, Porter AG (2000) Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma. J Biol Chem 275: 39920-39926.
39. Wang S, Miura M, Jung Y, Zhu H, Gagliardini V, et al. (1996) Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J Biol Chem 271: 20580-20587.
40. Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J (1997) Inhibition of ICE slows ALS in mice. Nature 388: 31.
41. Friedlander RM, Gagliardini V, Hara H, Fink KB, Li W, et al. (1997) Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med 185: 933-940.
42. Furuya T, Hayakawa H, Yamada M, Yoshimi K, Hisahara S, et al. (2004) Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci 24: 1865-1872.
43. Kang SJ, Sanchez I, Jing N, Yuan J (2003) Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis. J Neurosci 23: 5455-5460.
44. Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, et al. (1999) Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature 399: 263-267.
45. Bartlett WP, Banker GA (1984) An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts. J Neurosci 4: 1944-1953.
46. Haroutunian V, Katsel P, Schmeidler J (2007) Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiol Aging.
47. Haroutunian V, Perl DP, Purohit DP, Marin D, Khan K, et al. (1998) Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Arch Neurol 55: 1185-1191.
48. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, et al. (1991) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41: 479-486.
49. Dracheva S, Marras SA, Elhakem SL, Kramer FR, Davis KL, et al. (2001) N-methyl D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. Am J Psychiatry 158: 1400-1410.
50. Dracheva S, Elhakem SL, Marcus SM, Siever LJ, McGurk SR, et al. (2003) RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. J Neurochem 87: 1402-1412.
51. Dracheva S, Elhakem SL, McGurk SR, Davis KL, Haroutunian V (2004) GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. J Neurosci Res 76: 581-592.
52. Dracheva S, McGurk SR, Haroutunian V (2005) mRNA expression of AMPA receptors and AMPA receptor binding proteins in the cerebral cortex of elderly schizophrenics. J Neurosci Res 79: 868-878.
53. Beecham GW, Martin ER, Li YJ, Slifer MA, Gilbert JR, et al. (2009) Genomewide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. Am J Hum Genet 84: 35-43.
54. Armitage P (1955) Tests for Linear Trends in Proportions and Frequencies. Biometrics 11: 375-386.
55. Pounds S, Morris SW (2003) Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values. Bioinformatics 19: 1236-1242.