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Volumn 1160, Issue , 2009, Pages 117-120

RXFP1 couples to the Gαi3-Gβγ-PI3K-PKCζ pathway via the final 10 amino acids of the receptor C-terminal tail

Author keywords

cAMP; G protein; PI3K; PKC; RXFP1; RXFP2

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ZETA; PROTEIN RXFP1; PROTEIN RXFP2; UNCLASSIFIED DRUG; G PROTEIN BETA GAMMA; G-PROTEIN BETA GAMMA; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; RECEPTOR; RXFP1 PROTEIN, HUMAN;

EID: 64549151615     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2008.03813.x     Document Type: Conference Paper
Times cited : (4)

References (11)
  • 1
    • 0037169071 scopus 로고    scopus 로고
    • Activation of orphan receptors by the hormone relaxin
    • Hsu, S.Y., K. Nakabayashi, S. Nishi, et al. 2002. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674.
    • (2002) Science , vol.295 , pp. 671-674
    • Hsu, S.Y.1    Nakabayashi, K.2    Nishi, S.3
  • 2
    • 0037200034 scopus 로고    scopus 로고
    • INSL3/Leydig insulin-like peptide activates the LGR8 receptor in testis descent
    • Kumagai, J., S.Y. Hsu, H. Matsumi, et al. 2002. INSL3/Leydig insulin-like peptide activates the LGR8 receptor in testis descent. J. Biol. Chem. 277: 31283-31286.
    • (2002) J. Biol. Chem , vol.277 , pp. 31283-31286
    • Kumagai, J.1    Hsu, S.Y.2    Matsumi, H.3
  • 3
    • 33644589069 scopus 로고    scopus 로고
    • International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides
    • Bathgate, R.A.D., R. lvell, B.M. Sanborn, et al. 2006. International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacol. Rev. 58: 7-31.
    • (2006) Pharmacol. Rev , vol.58 , pp. 7-31
    • Bathgate, R.A.D.1    lvell, R.2    Sanborn, B.M.3
  • 4
    • 0037424265 scopus 로고    scopus 로고
    • H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
    • Sudo, S., J. Kumagai, S. Nishi, et al. 2003. H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J. Biol. Chem. 278: 7855-7862.
    • (2003) J. Biol. Chem , vol.278 , pp. 7855-7862
    • Sudo, S.1    Kumagai, J.2    Nishi, S.3
  • 5
    • 18044378198 scopus 로고    scopus 로고
    • Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8)
    • Halls, M.L., C.P. Bond, S. Sudo, et al. 2005. Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8). J. Pharmacol. Exp. Ther. 313: 677-687.
    • (2005) J. Pharmacol. Exp. Ther , vol.313 , pp. 677-687
    • Halls, M.L.1    Bond, C.P.2    Sudo, S.3
  • 6
    • 34347270603 scopus 로고    scopus 로고
    • Defining the LGR8 residues involved in binding insulin-like peptide 3
    • Scott, D.J., T.N. Wilkinson, S. Zhang, et al. 2007. Defining the LGR8 residues involved in binding insulin-like peptide 3. Mol. Endocrinol. 21: 1699-1712.
    • (2007) Mol. Endocrinol , vol.21 , pp. 1699-1712
    • Scott, D.J.1    Wilkinson, T.N.2    Zhang, S.3
  • 7
    • 33748746259 scopus 로고    scopus 로고
    • The mode of interaction of the relaxin-like factor (RLF) with the leucine rich repeat G-protein activated receptor 8
    • Bullesbach, E.E. & C. Schwabe. 2007. The mode of interaction of the relaxin-like factor (RLF) with the leucine rich repeat G-protein activated receptor 8. J. Biol. Chem. 281: 26136-26143.
    • (2007) J. Biol. Chem , vol.281 , pp. 26136-26143
    • Bullesbach, E.E.1    Schwabe, C.2
  • 8
    • 0034464024 scopus 로고    scopus 로고
    • The three sub-families of leucine rich repeat containing G-protein coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7
    • Hsu, S.Y., M. Kudo, T. Chen, et al. 2000. The three sub-families of leucine rich repeat containing G-protein coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol. Endocrinol. 14: 1257-1271.
    • (2000) Mol. Endocrinol , vol.14 , pp. 1257-1271
    • Hsu, S.Y.1    Kudo, M.2    Chen, T.3
  • 9
    • 33745226248 scopus 로고    scopus 로고
    • Relaxin family peptide receptors 1 and 2 modulate cAMP signaling by distinct mechanisms
    • Halls, M.L., R.A. Bathgate & R.J. Summers. 2006. Relaxin family peptide receptors 1 and 2 modulate cAMP signaling by distinct mechanisms. Mol. Pharmacol. 70: 214-226.
    • (2006) Mol. Pharmacol , vol.70 , pp. 214-226
    • Halls, M.L.1    Bathgate, R.A.2    Summers, R.J.3
  • 10
    • 0037503879 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3',5'-monophosphate by relaxin
    • Nguyen, B.T., L. Yang, B.M. Sanborn, et al. 2003. Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3',5'-monophosphate by relaxin. Mol. Endocrinol. 17: 1075-1084.
    • (2003) Mol. Endocrinol , vol.17 , pp. 1075-1084
    • Nguyen, B.T.1    Yang, L.2    Sanborn, B.M.3
  • 11
    • 15444366198 scopus 로고    scopus 로고
    • Relaxin stimulates protein kinase C ζ translocation: Requirement for cyclic adenosine 3',5'-monophosphate production
    • Nguyen, B.T. & C.W. Dessauer. 2005. Relaxin stimulates protein kinase C ζ translocation: requirement for cyclic adenosine 3',5'-monophosphate production. Mol. Endocrinol. 19: 1012-1023.
    • (2005) Mol. Endocrinol , vol.19 , pp. 1012-1023
    • Nguyen, B.T.1    Dessauer, C.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.