Endometrial cysteine-rich secretory protein 3 is inhibited by human chorionic gonadotrophin, and is increased in the decidua of tubal ectopic pregnancy

Molecular Human Reproduction

Volumn 15, Issue 5, 2009, Pages 287-294

  Horne, Andrew W ^a   Duncan, W C ^a   King, A E ^a   Burgess, S ^a   Lourenco, P C ^a   Cornes, P ^a   Ghazal, P ^a   Williams, A R ^a   Udby, L ^b   Critchley, H O D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Rigshospitalet   (Denmark)

Author keywords

CRISP 3; Decidualized endometrium; Ectopic pregnancy; hCG

Indexed keywords

BIOLOGICAL MARKER; CHORIONIC GONADOTROPIN; CYSTEINE RICH SECRETORY PROTEIN 3; PROGESTERONE; SECRETORY PROTEIN; UNCLASSIFIED DRUG; CRISP3 PROTEIN, HUMAN; SALIVA PROTEIN; SEMINAL PLASMA PROTEIN;

ARTICLE; CELL IMMORTALIZATION; CELL STIMULATION; CONTROLLED STUDY; DECIDUA; DECIDUALIZATION; ECTOPIC PREGNANCY; ENDOMETRIUM CELL; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HORMONE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PREGNANCY TERMINATION; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPONTANEOUS ABORTION; WESTERN BLOTTING; ADOLESCENT; ADULT; BLOOD; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; ENDOMETRIUM; GENETICS; METABOLISM; MICROARRAY ANALYSIS; MIDDLE AGED; NIDATION; PATHOLOGY; PREGNANCY; TROPHOBLAST;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CELL LINE; CHORIONIC GONADOTROPIN; DECIDUA; EMBRYO IMPLANTATION; ENDOMETRIUM; FEMALE; HUMANS; MICROARRAY ANALYSIS; MIDDLE AGED; PREGNANCY; PREGNANCY, ECTOPIC; PROGESTERONE; SALIVARY PROTEINS AND PEPTIDES; SEMINAL PLASMA PROTEINS; TROPHOBLASTS; YOUNG ADULT;

EID: 64549146193     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gap019     Document Type: Article

References (32)

1. American Society for Reproductive Medicine. Medical treatment of ectopic pregnancy. Fertil Steril 2006;86:S96-S102.
2. Ball E, Bulmer JN, Ayis S, Lyall F, Robson SC. Late sporadic miscarriage is associated with abnormalities in spiral artery transformation and trophoblast invasion. J Pathol 2006;208:535-542.
3. Birkhahn RH, Gaeta TJ, Paraschiv D, Bove JJ, Suzuki T, Katoh H, Nagai R. Serum levels of myoglobin, creatine phosphokinase, and smooth muscle heavy-chain myosin in patients with ectopic pregnancy. Ann Emerg Med 2001;38:628-632.
4. Bjartell A, Johansson R, Björk T, Gadaleanu V, Lundwall A, Lilja H, Kjeldsen L, Udby L. Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland. Prostate 2006;66 591-603.
5. Corker CS, Davidson DW. A radioimmunoassy for testosterone in various biological fluids without chromatography. J Steroid Biochem 1978; 9:373-374.
6. Dalgetty DM, Sallenave JM, Critchley HO, Williams AR, Tham WY, King AE, Horne AW. Altered secretory leukocyte protease inhibitor expression in the uterine decidua of tubal compared with intrauterine pregnancy. Hum Reprod 2008;23:1485-1490.
7. Develioglu OH, Askalli C, Uncu G, Samli B, Daragenli O. Evaluation of serum creatine kinase in ectopic pregnancy with reference to tubal status and histopathology. Brit J Obst Gynaecol 2002;109 121-128.
8. Duncan WC, Sweeting VM, Cawood P, Illingworth PJ. Measurement of creatine kinase activity and diagnosis of ectopic pregnancy. Brit J Obst Gynaecol 1995;102:233-237.
9. Farquhar CM. Ectopic pregnancy. Lancet 2005;366:583-591.
10. Florio P, Severi FM, Bocchi C, Luisi S, Mazzini M, Danero S, Torricelli M, Petraglia F. Single serum activin a testing to predict ectopic pregnancy. J Clin Endocrinol Metab 2007;92:1748-1753.
11. Friess H, Ding J, Kleeff J, Liao Q, Berberat PO, Hammer J, Buchler MW. Identification of disease-specific genes in chronic pancreatitis using DNA array technology. Ann Surg 2001;234:769-778.
12. Gibbs GM, O'Bryan MK. Cysteine rich secretory proteins in reproduction and venom. Soc Reprod Fertil Suppl 2007;65:261-267.
13. Hearn JP, Gidley-Baird AA, Hodges JK, Summers PM, Webley GE. Embryonic signals during the peri-implantation period in primates. J Reprod Fertil Suppl 1988;36:49-58.
14. Hess AP, Hamilton AE, Talbi S, Dosiou C, Nyegaard M, Nayak N, Genbecev-Krtolica O, Mavrogianis P, Ferrer K, Kruessel J et al. Decidual stromal cell response to paracrine signals from the trophoblast: Amplification of immune and angiogenic modulators. Biol Reprod 2007;76:102-117.
15. Hombach-Klonisch S, Kehlen A, Fowler PA, Huppertz B, Jmgert JF, Bischoff G, Schluter E, Buchmann J, Klonisch T. Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells. J Mol Endocrinol 2005;34 517-534.
16. Horne AW, van den Driesche S, King AE, Burgess S, Myers M, Ludlow H, Lourenco P, Ghazal P, Williams AR, Critchley HO et al. Endometrial inhibin/activin beta-B subunit expression is related to decidualization and is reduced in tubal ectopic pregnancy. J Clin Endocrinol Metab 2008;93:2375-2382.
17. Kjeldsen L, Cowland JB, Johnsen AH, Borregaard N. SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein. FEBS Lett 1996;380:246-250.
18. Koh EA, Illingworth PJ, Duncan WC, Critchley HO. Immunolocalization of bcl-2 protein in human endometrium in the menstrual cycle and simulated early pregnancy. Hum Reprod 1995;10:1557-1562.
19. Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD. The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. Eur J Biochem 1996;236:827-836.
20. Mukul LV, Teal SB. Current management of ectopic pregnancy. Obstet Gynecol Clin North Am. 2007;34:403-419.
21. Nakayama J, Aoki D, Smga T, Akama TO, Ishizone S, Yamaguchi H, Imakawa K, Nadano D, Fazleabas AT, Katsuyama T et al. Implantation-dependent expression of trophinin by maternal Fallopian tube epithelia during tubal pregnancies: Possible role of human chorionic gonadotrophin on ectopic pregnancy. Am J Pathol 2003; 163:2211-2219.
22. Robson SJ, O'shea RT. Undiagnosed ectopic pregnancy: A retrospective analysis of 31 'missed' ectopic pregnancies at a teaching hospital. Aust N Z J Obstet Gynaecol 1996;36:182-185.
23. Saving Mothers' Lives. Confidential Enquiry into Maternal Deaths 2003-5. 2008; ISBN: 978-0-9533536-8-2.
24. Savaris RF, Hamilton AE, Lessey BA, Giudice LC. Endometrial gene expression in early pregnancy: Lessons from human ectopic pregnancy. Reprod Sci 2008;15:797-816.
25. Schleicher E, Wieland OH. Evaluation of the Bradford method for protein determination in body fluids. J Clin Chem Clin Biochem 1978; 533-534.
26. Schroeder A, Mueller O, Stocker S, Salowsky R, Leiber M, Gassmann M, Lightfoot S, Menzel W, Granzow M, Ragg T. The RIN: An RNA integrity number for assigning integrity values to RNA measurements. BMC Mol Biol 2006;7:3.
27. Sherwin JR, Sharkey AM, Cameo P, Mavrogianis PM, Catalano RD, Edassery S, Fazleabas AT. Identification of novel genes regulated by chorionic gonadotropin in baboon endometrium during the window of implantation. Endocrinology 2007;148:618-626.
28. Stintzi A, Heitz T, Prasad V, Wiedemann-Merdinoglu S, Kauffmann S, Geoffroy P, Legrand M, Fritig B. Plant 'pathogenesis-related' proteins and their role in defense against pathogens. Biochimie 1993;75 687-706.
29. Udby L, Cowland JB, Johnsen AH, Sorensen OE, Borregaard N, Kjeldsen L. An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions. J Immunol Methods 2002a;263:43-55.
30. Udby L, Calafat J, Sorensen OE, Borregaard N, Kjeldsen L. Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils. J Leukoc Biol 2002b;72:462-469.
31. Udby L, Bjartell A, Malm J, Egesten A, Lundwall A, Cowland JB, Borregaard N, Kjeldsen L. Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract. J Androl 2005;26:333-342.
32. Wegner NT, Mershon JL. Evaluation of leukemia inhibitory factor as a marker of ectopic pregnancy. Am J Obstet Gynecol 2001;184 1074-1076.