Effective purification of ginsenosides from cultured wild ginseng roots, red ginseng, and white ginseng with macroporous resins

Journal of Microbiology and Biotechnology

Volumn 18, Issue 11, 2008, Pages 1789-1791

  Li, Huayue ^a   Lee, Jae Hwa ^a   Ha, Jong Myung ^a  

^a Silla University   (South Korea)

Author keywords

Cultured wild ginseng roots; Ginsenoside; HPLC; Macroporous resin; Purification

Indexed keywords

ALCOHOL; GINSENG EXTRACT; GINSENOSIDE; RESIN; ION EXCHANGE RESIN; PLANT EXTRACT; POLACRILIN;

ADSORPTION CHROMATOGRAPHY; ADVENTITIOUS ROOT; ARTICLE; CONTENT ANALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; GINSENG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLANT ROOT; POROSITY; STRUCTURE ANALYSIS; ULTRASOUND; WILD PLANT; BIOTECHNOLOGY; CHEMISTRY; EVALUATION; GROWTH, DEVELOPMENT AND AGING; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METHODOLOGY;

PANAX GINSENG;

BIOTECHNOLOGY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; GINSENOSIDES; ION EXCHANGE RESINS; PANAX; PLANT EXTRACTS; PLANT ROOTS; RESINS, SYNTHETIC;

EID: 64549135864     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0800.192     Document Type: Article

References (15)

1. Cai, X., Z. Q. Liu, P. X. Wang, and L. Liu. 2001. Study on purification process of ginsenosides with macroreticular resin. Chinese Trad. Patent Med. 23: 631-634.
2. Fu, Y., Y. Zu, W. Liu, C. Hou, L. Chen, S. Li, X. Shi, and M. Tong. 2007. Preparative separation of vitexin and isovitexin from pigeonpea extracts with macroporous resins. J. Chromatogr. A 1139: 206-213.
3. Gao, M., W. Huang, and C. Z. Liu. 2007. Separation of scutellarin from crude extracts of Erigeron breviscapus (vant.) Hand. Mazz. by macroporous resins. J. Chromatogr. B 858: 22-26.
4. Huang, Z., G. Fang, and B. Zhang. 2007. Separation and purification of arabinogalactan obtained from Larix gmelinii by macroporous resin adsorption. J. Forest. Res. 18: 81-83.
5. Kim, H. A., S. Kim, S. H. Chang, H. J. Hwang, and Y. Choi. 2007. Anti-arthritic effect of ginsenoside Rb1 on collagen induced arthritis in mice. Int. Immunopharmacol. 7: 1286-1291.
6. Kimura, Y., M. Sumiyoshi, K. Kawahira, and M. Sakanaka. 2006. Effects of ginseng saponins isolated from red ginseng roots on burn wound healing in mice. Brit. J. Pharmacol. 148: 860-870.
7. Kwak, Y. S., M. S. Hwang, S. C. Kim, C. S. Kim, J. H. Do, and C. K. Park. 2006. A growth inhibition effect of saponin from red ginseng on some pathogenic microorganisms. J. Ginseng Res. 30: 128-131.
8. Lau, A. J., B. H. Seo, S. O. Woo, and H. L. Koh. 2004. High-performance liquid chromatographic method with quantitative comparisons of whole chromatograms of raw and steamed Panax notoginseng. J. Chromatogr. A 1057: 141-149.
9. Li, L., J. L. Zhang, Y. X. Sheng, G. Ye, H. Z. Guo, and D. A. Guo. 2004. Simultaneous quantification of six major active saponins of Panax notoginseng by high-performance liquid chromatography-UV method. J. Pharmaceut. Biomed. 38: 45-51.
10. Sun, A., Q. Sun, and R. Liu. 2007. Preparative isolation and purification of flavones compounds from Sophora japonica L. by highspeed counter-current chromatography combined with macroporous resin column separation. J. Sep. Sci. 30: 1013-1018.
11. Tran, Q. L., M. M. Than, Y. Tezuka, A. H. Banskota, K. Kouda, H. Watanabe, et al. 2003. Wild ginseng grows in Myanmar. Chem. Pharm. Bull. 51: 679-682.
12. Vanhaelen-Fastre, R. J., M. L. Faes, and M. H. Vanhaelen. 2000. High-performance thin-layer chromatographic determination of six major ginsenosides in Panax ginseng. J. Chromatogr. A 868: 269-276.
13. Wan, J. B., S. Li, J. M. Chen, and Y. T. Wang. 2007. Chemical characteristics of three medicinal plants of the Panax genus determined by HPLC-ELSD. J. Sep. Sci. 30: 825-832.
14. Yun, T. K. 2003. Experimental and epidemiological evidence on non-organ specific cancer preventive effect of Korean ginseng and identification of active compounds. Mutat. Res. 523-524: 63-74.
15. Zhang, Q. F., Z. T. Jiang, H. J. Gao, and R. Li. 2008. Recovery of vanillin from aqueous solutions using macroporous adsorption resins. Eur. Food. Res. Technol. 226: 377-383.