Role of relaxin in human osteoclastogenesis

Annals of the New York Academy of Sciences

Volumn 1160, Issue , 2009, Pages 221-225

  Facciolli, Arianna ^a   Ferlin, Alberto ^a   Gianesello, Lisa ^a   Pepe, Anastasia ^a   Foresta, Carlo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Bone metastasis; Osteoclastogenesis; Osteoclasts; Relaxin; RXFP1

Indexed keywords

RELAXIN;

ADULT; BONE METASTASIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; GENE; HORMONAL REGULATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; NORMAL HUMAN; OSTEOCLAST; PERIPHERAL BLOOD MONONUCLEAR CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RLN 2 GENE; RXFP1 GENE;

EID: 64549135098     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2008.03788.x     Document Type: Conference Paper

References (8)

1. Kristiansson, P., C. Holding, S. Hughes, et al. 2005. Does human relaxin-2 affect peripheral blood mononuclear cells to increase inflammatory mediators in pathologic bone loss? Ann. N. Y. Acad. Sci. 1041: 317-319.
2. Hombach-Klonisch, S., J. Bialek, B. Trojanowicz, et al. 2006. Relaxin enhances the oncogenic potential of human thyroid carcinoma cells. Am. J. Pathol. 169: 617-632.
3. Hombach-Klonisch, S., J. Buchmann, S. Sarun, et al. 2000. Relaxin - like factor (RLF) is differentially expressed in the normal and neoplastic human mammary gland. Cancer 89: 2161-2168.
4. Silvertown, J. D., J. Ng, T. Sato, et al. 2006. H2 relaxin overexpression increases in vivo prostate xenograft tumor growth and angiogenesis. Int. J. Cancer 118: 62-73.
5. Parsell, D. A., J. Y. Mak, E. P. Amento, et al. 1996. Relaxin binds to and elicits a response from cells of the human monocytic cell line, THP-1. J. Biol. Chem. 271: 27936-27941.
6. Thompson, V. C., T. G. Morris, D. R. Cochrane, et al. 2006. Relaxin becomes upregulated during prostate cancer progression to androgen independence and is negatively regulated by androgens. Prostate 66: 1698-1709.
7. Ferlin, A., A. Pepe, L. Gianesello, et al. 2008. Mutations in the insulin-like factor 3 receptor are associated with osteoporosis. J. Bone Miner. Res. 23: 683-693.
8. Matsuzaki, K., K. Katayama, Y. Takahashi, et al. 1999. Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene. Endocrinology 140: 925-932.