Simple and efficient metal-free hydroarylation and hydroalkylation using strongly acidic ion-exchange resin

Chemistry Letters

Volumn 38, Issue 1, 2009, Pages 42-43

  Das, Biswanath ^a   Krishnaiah, Martha ^a   Laxminarayana, Keetha ^a   Damodar, Kongara ^a   Kumar, D Nandan ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 64549121304     PISSN: 03667022     EISSN: 13480715     Source Type: Journal    
DOI: 10.1246/cl.2009.42     Document Type: Article

References (23)

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22. General procedure for hydroarytation and hydroalkylation: To a stirred solution of an arene or 1.3-dicarbonyl compound (1 mmol) and styrene (1.1mmol) Amberlyst-15 (100mg) was added. The mixture was allowed to reflux at 80 °C and the reaction was monitored by TLC. After completion the mixture was cooled and filtered. The filtrate was concentrated and the residue was subjected to column chromatography (silica get, hexane-EtOAc) to obtain pure hydroarylated or hydroalkylated styrene. The catalytic efficiency of Amberlyst-15 was tested on the reaction of styrene and 2-naphlhol (Table 1, Entry a) following the above method. The yields of 3a were found to be 98, 96, 95, and 92% in four consecutive uses of the catalyst.
23. Supporting Information is available electrically on the CSJ-Journal Web site, http://www.csj.jp/journals/chem-lett/index.html.