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Volumn 34, Issue 3, 2009, Pages 777-786

Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines

Author keywords

Anthocyanins; Breast; Cancer; Cytotoxicity; Polyphenols; Prostate; Tannins

Indexed keywords

ANTHOCYANIN; PHYTOHEMAGGLUTININ; PLANT EXTRACT; POLYPHENOL; STRAWBERRY EXTRACT; TANNIN; UNCLASSIFIED DRUG;

EID: 64549118290     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000203     Document Type: Article
Times cited : (26)

References (55)
  • 1
    • 0346767298 scopus 로고    scopus 로고
    • Joint WHO/FAO Expert Consultation on Diet, Nutrition and the Prevention of Chronic Diseases
    • Geneva, Anon
    • Anon: Joint WHO/FAO Expert Consultation on Diet, Nutrition and the Prevention of Chronic Diseases. WHO technical report series, Geneva, 2002.
    • (2002) WHO technical report series
  • 2
    • 0030411296 scopus 로고    scopus 로고
    • Vegetables, fruit and cancer prevention: A review
    • Steinmetz KA and Potter JD: Vegetables, fruit and cancer prevention: A review. J Am Diet Assoc 96: 1027-1039, 1996.
    • (1996) J Am Diet Assoc , vol.96 , pp. 1027-1039
    • Steinmetz, K.A.1    Potter, J.D.2
  • 3
    • 0035165044 scopus 로고    scopus 로고
    • The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence
    • Simopoulos AP: The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence. J Nutr 131: S3065-S3073, 2001.
    • (2001) J Nutr , vol.131
    • Simopoulos, A.P.1
  • 5
    • 34447505041 scopus 로고    scopus 로고
    • Berry phytochemicals, genomic stability and cancer
    • Duthie SJ: Berry phytochemicals, genomic stability and cancer. Mol Nutr Food Res 51: 665-674, 2007.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 665-674
    • Duthie, S.J.1
  • 6
    • 0029854544 scopus 로고    scopus 로고
    • Free radicals, proteins and DNA: Oxidative damage versus redox regulation
    • Halliwell B: Free radicals, proteins and DNA: oxidative damage versus redox regulation. Biochem Soc Trans 24: 1023-1027, 1996.
    • (1996) Biochem Soc Trans , vol.24 , pp. 1023-1027
    • Halliwell, B.1
  • 7
    • 33746493949 scopus 로고    scopus 로고
    • Markers of oxidative DNA damage in human interventions with fruit and berries
    • Freese R: Markers of oxidative DNA damage in human interventions with fruit and berries. Nutr Cancer 54: 143-147, 2006.
    • (2006) Nutr Cancer , vol.54 , pp. 143-147
    • Freese, R.1
  • 8
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan GI and Vousden KH: Proliferation, cell cycle and apoptosis in cancer. Nature 411: 342-348, 2001.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 9
    • 80051843643 scopus 로고    scopus 로고
    • Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties
    • Zhang Y, Seeram NP, Lee R, Feng L and Heber D: Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties. J Agric Food Chem 56: 670-675, 2008.
    • (2008) J Agric Food Chem , vol.56 , pp. 670-675
    • Zhang, Y.1    Seeram, N.P.2    Lee, R.3    Feng, L.4    Heber, D.5
  • 10
    • 4744364585 scopus 로고    scopus 로고
    • Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumourigenic colonic cell growth
    • Zhao C, Giusti MM, Malik M, Moyer, MP and Magnuson BA: Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumourigenic colonic cell growth. J Agric Food Chem 52: 6122-6128, 2004.
    • (2004) J Agric Food Chem , vol.52 , pp. 6122-6128
    • Zhao, C.1    Giusti, M.M.2    Malik, M.3    Moyer, M.P.4    Magnuson, B.A.5
  • 11
    • 0032797136 scopus 로고    scopus 로고
    • The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells
    • Ye X, Krohn RL, Liu W, et al: The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells. Mol Cell Biochem 196: 99-108, 1999.
    • (1999) Mol Cell Biochem , vol.196 , pp. 99-108
    • Ye, X.1    Krohn, R.L.2    Liu, W.3
  • 12
    • 34948874866 scopus 로고    scopus 로고
    • Three nordic berries inhibit intestinal tumourigenesis in multiple intestinal neoplasia/+ mice by modulating β-catenin signalling in the mucosa
    • Misikangas M, Paraji AM, Paivarinta E, et al: Three nordic berries inhibit intestinal tumourigenesis in multiple intestinal neoplasia/+ mice by modulating β-catenin signalling in the mucosa. J Nutr 137: 2285-2290, 2007.
    • (2007) J Nutr , vol.137 , pp. 2285-2290
    • Misikangas, M.1    Paraji, A.M.2    Paivarinta, E.3
  • 13
    • 33846121301 scopus 로고    scopus 로고
    • Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac
    • Bobe G, Wang B, Seeram NP, Nair MG and Bourquin LD: Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac. J Agric Food Chem 54: 9322-9328, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 9322-9328
    • Bobe, G.1    Wang, B.2    Seeram, N.P.3    Nair, M.G.4    Bourquin, L.D.5
  • 14
    • 0035092599 scopus 로고    scopus 로고
    • Inhibition of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat oesophagus by dietary freeze-dried strawberries
    • Carlton PS, Kresty LA, Siglin JC, Morse MA, Lu J, Morgan C and Stoner GD: Inhibition of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat oesophagus by dietary freeze-dried strawberries. Carcinogenesis 22: 441-446, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 441-446
    • Carlton, P.S.1    Kresty, L.A.2    Siglin, J.C.3    Morse, M.A.4    Lu, J.5    Morgan, C.6    Stoner, G.D.7
  • 15
    • 34548481540 scopus 로고    scopus 로고
    • Cancer prevention with freeze-dried berries and berry components
    • Stoner GD, Wand LS, Zikri N, et al: Cancer prevention with freeze-dried berries and berry components. Semin Cancer Biol 17: 403-410, 2007.
    • (2007) Semin Cancer Biol , vol.17 , pp. 403-410
    • Stoner, G.D.1    Wand, L.S.2    Zikri, N.3
  • 16
    • 0037229268 scopus 로고    scopus 로고
    • Induction of apoptosis in cancer cells by bilberry (Vaccinium myrtillus) and the anthocyanins
    • Katsube N, Iwashita K, Tsushida T, Yamaki K and Kobori M: Induction of apoptosis in cancer cells by bilberry (Vaccinium myrtillus) and the anthocyanins. J Agric Food Chem 51: 68-75, 2003.
    • (2003) J Agric Food Chem , vol.51 , pp. 68-75
    • Katsube, N.1    Iwashita, K.2    Tsushida, T.3    Yamaki, K.4    Kobori, M.5
  • 17
    • 33746878757 scopus 로고    scopus 로고
    • Absorption of anthocyanins from blueberry extracts by Caco-2 human intestinal cell monolayers
    • Yi W, Akoh CC, Fischer J and Krewer G: Absorption of anthocyanins from blueberry extracts by Caco-2 human intestinal cell monolayers. J Agric Food Chem 54: 5651-5658, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 5651-5658
    • Yi, W.1    Akoh, C.C.2    Fischer, J.3    Krewer, G.4
  • 18
    • 44349169060 scopus 로고    scopus 로고
    • Berry extracts exert different antiproliferative effects against cervical and colon cancer cells grown in vitro
    • McDougall GJ, Ross HA, Ikeji M and Stewart D: Berry extracts exert different antiproliferative effects against cervical and colon cancer cells grown in vitro. J Agric Food Chem 56: 3016-3023, 2008.
    • (2008) J Agric Food Chem , vol.56 , pp. 3016-3023
    • McDougall, G.J.1    Ross, H.A.2    Ikeji, M.3    Stewart, D.4
  • 19
    • 13944281987 scopus 로고    scopus 로고
    • Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2)
    • Ramos S, Alia M, Bravo L and Goya L: Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2). J Agric Food Chem 53: 1271-1280, 2005.
    • (2005) J Agric Food Chem , vol.53 , pp. 1271-1280
    • Ramos, S.1    Alia, M.2    Bravo, L.3    Goya, L.4
  • 20
    • 19544370181 scopus 로고    scopus 로고
    • Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries
    • Han C, Ding H, Casto B, Stoner GD and D'Ambrosio SM: Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries. Nutr Cancer 51: 207-217, 2005.
    • (2005) Nutr Cancer , vol.51 , pp. 207-217
    • Han, C.1    Ding, H.2    Casto, B.3    Stoner, G.D.4    D'Ambrosio, S.M.5
  • 21
    • 33745958257 scopus 로고    scopus 로고
    • In-vitro effects of polyphenols from cocoa and β-sitosterol on the growth of human prostate cancer and normal cells
    • Jourdain C, Tenca G, Deguercy A, Troplin P and Poelman D: In-vitro effects of polyphenols from cocoa and β-sitosterol on the growth of human prostate cancer and normal cells. Eur J Cancer Prev 15: 353-361, 2006.
    • (2006) Eur J Cancer Prev , vol.15 , pp. 353-361
    • Jourdain, C.1    Tenca, G.2    Deguercy, A.3    Troplin, P.4    Poelman, D.5
  • 22
    • 33750492252 scopus 로고    scopus 로고
    • Treatment of Mcf-7 breast Cancer cells with a red grape wine polyphenol fraction results in disruption of calcium homeostasis and cell cycle arrest causing selective cytotoxicity
    • Hakimuddin F, Paliyath G and Meckling K: Treatment of Mcf-7 breast Cancer cells with a red grape wine polyphenol fraction results in disruption of calcium homeostasis and cell cycle arrest causing selective cytotoxicity. J Agric Food Chem 54: 7912-7923, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 7912-7923
    • Hakimuddin, F.1    Paliyath, G.2    Meckling, K.3
  • 23
    • 33947159182 scopus 로고    scopus 로고
    • Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status
    • Al-Ayyoubi S and Gali-Muhtasib H: Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status. Mol Carcinog 46: 176-186, 2007.
    • (2007) Mol Carcinog , vol.46 , pp. 176-186
    • Al-Ayyoubi, S.1    Gali-Muhtasib, H.2
  • 24
    • 33846131249 scopus 로고    scopus 로고
    • Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro
    • Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS and Heber D: Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro. J Agric Food Chem 54: 9329-9339, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 9329-9339
    • Seeram, N.P.1    Adams, L.S.2    Zhang, Y.3    Lee, R.4    Sand, D.5    Scheuller, H.S.6    Heber, D.7
  • 25
    • 33845868507 scopus 로고    scopus 로고
    • Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts
    • Ross H, McDougall GJ and Stewart D: Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts. Phytochemistry 68: 218-228, 2007.
    • (2007) Phytochemistry , vol.68 , pp. 218-228
    • Ross, H.1    McDougall, G.J.2    Stewart, D.3
  • 26
    • 80051843643 scopus 로고    scopus 로고
    • Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties
    • Zhang Y, Seeram NP, Lee R, Feng L and Heber D: Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties. J Agric Food Chem 56: 670-675, 2008.
    • (2008) J Agric Food Chem , vol.56 , pp. 670-675
    • Zhang, Y.1    Seeram, N.P.2    Lee, R.3    Feng, L.4    Heber, D.5
  • 27
    • 0000359845 scopus 로고
    • Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents
    • Singleton VL and Rossi JA Jr: Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic 16: 144-158, 1965.
    • (1965) Am J Enol Vitic , vol.16 , pp. 144-158
    • Singleton, V.L.1    Rossi Jr, J.A.2
  • 28
    • 10844284696 scopus 로고    scopus 로고
    • Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
    • Ramirez RD, Sheridan S, Girard L, et al: Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 64: 9027-9034, 2004.
    • (2004) Cancer Res , vol.64 , pp. 9027-9034
    • Ramirez, R.D.1    Sheridan, S.2    Girard, L.3
  • 29
    • 1942518247 scopus 로고    scopus 로고
    • Gene amplification of atypical PKC-binding PARD3 in radiation-transformed neoplastic retinal pigment epithelial cell lines
    • Zitzelsberger H, Hieber L, Richter H, Unger K, Briscoe CV, Peddie C and Riches A: Gene amplification of atypical PKC-binding PARD3 in radiation-transformed neoplastic retinal pigment epithelial cell lines. Genes Chromosomes Cancer 40: 55-59, 2004.
    • (2004) Genes Chromosomes Cancer , vol.40 , pp. 55-59
    • Zitzelsberger, H.1    Hieber, L.2    Richter, H.3    Unger, K.4    Briscoe, C.V.5    Peddie, C.6    Riches, A.7
  • 30
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov SR, Kozaklewicz BK, Holst CR, Stampfer MR, Haupt LM and Tlsty TD: Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 409: 633-637, 2001.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozaklewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 31
    • 0033637345 scopus 로고    scopus 로고
    • Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines
    • Kampa M, Hatzoglou A, Notas G, et al: Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines. Nutr Cancer 37: 223-233, 2000.
    • (2000) Nutr Cancer , vol.37 , pp. 223-233
    • Kampa, M.1    Hatzoglou, A.2    Notas, G.3
  • 33
    • 20844438728 scopus 로고    scopus 로고
    • Phenolic composition and antioxidant activities in flesh and achenes of strawberries (Fragaria ananassa)
    • Aaby K, Skrede G, and Wrolstad RE: Phenolic composition and antioxidant activities in flesh and achenes of strawberries (Fragaria ananassa). J Agric Food Chem 53: 4032-4040, 2005.
    • (2005) J Agric Food Chem , vol.53 , pp. 4032-4040
    • Aaby, K.1    Skrede, G.2    Wrolstad, R.E.3
  • 35
    • 80051852989 scopus 로고    scopus 로고
    • Ellagitannin composition of blackberry as determined by HPLC-ESI-MS and MALDI-TOF-MS
    • Hager TJ, Howard LR, Liyanage R, Lay JO and Prior RL: Ellagitannin composition of blackberry as determined by HPLC-ESI-MS and MALDI-TOF-MS. J Agric Food Chem 56: 661-669, 2008.
    • (2008) J Agric Food Chem , vol.56 , pp. 661-669
    • Hager, T.J.1    Howard, L.R.2    Liyanage, R.3    Lay, J.O.4    Prior, R.L.5
  • 36
    • 0141850470 scopus 로고    scopus 로고
    • Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation
    • Gu L, Kelm MA, Hammerstone JF, Beecher G, Holden J, Haytowitz D and Prior RL: Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation. J Agric Food Chem 51: 7513-7521, 2003.
    • (2003) J Agric Food Chem , vol.51 , pp. 7513-7521
    • Gu, L.1    Kelm, M.A.2    Hammerstone, J.F.3    Beecher, G.4    Holden, J.5    Haytowitz, D.6    Prior, R.L.7
  • 37
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson G, and Manach C: Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 81: S243-S255, 2005.
    • (2005) Am J Clin Nutr , vol.81
    • Williamson, G.1    Manach, C.2
  • 38
    • 0033853962 scopus 로고    scopus 로고
    • Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: Modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis
    • Agarwal C, Sharma Y and Agarwal R: Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis. Mol Carcinog 28: 129-138, 2000.
    • (2000) Mol Carcinog , vol.28 , pp. 129-138
    • Agarwal, C.1    Sharma, Y.2    Agarwal, R.3
  • 39
    • 0033941122 scopus 로고    scopus 로고
    • Polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G1 arrest and differentiation
    • Agarwal C, Sharma Y, Zhao J and Agarwal RA: Polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G1 arrest and differentiation. Clin Cancer Res 6: 2921-2930, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 2921-2930
    • Agarwal, C.1    Sharma, Y.2    Zhao, J.3    Agarwal, R.A.4
  • 40
    • 15244361547 scopus 로고    scopus 로고
    • Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel™
    • Lansky EP, Harrison G, Froom P and Jiang WG: Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel™. Invest New Drugs 23: 121-122, 2005.
    • (2005) Invest New Drugs , vol.23 , pp. 121-122
    • Lansky, E.P.1    Harrison, G.2    Froom, P.3    Jiang, W.G.4
  • 41
    • 34249863077 scopus 로고    scopus 로고
    • Berry phenolic extracts modulate the expression of p21(WAF1) and Bax but not Bcl-2 in HT-29 colon cancer cells
    • Wu QK, Koponen JM, Mykkanen HM and Torronen AR: Berry phenolic extracts modulate the expression of p21(WAF1) and Bax but not Bcl-2 in HT-29 colon cancer cells. J Agric Food Chem 55: 1156-1163, 2007.
    • (2007) J Agric Food Chem , vol.55 , pp. 1156-1163
    • Wu, Q.K.1    Koponen, J.M.2    Mykkanen, H.M.3    Torronen, A.R.4
  • 43
    • 33747226701 scopus 로고    scopus 로고
    • Cytotoxicity of bioactive polymeric fractions from grape cell culture on human hepatocellular carcinoma, murine leukemia and non-cancerous PK15 kidney cells
    • Jo JY, de Mejia EG and Lila MA: Cytotoxicity of bioactive polymeric fractions from grape cell culture on human hepatocellular carcinoma, murine leukemia and non-cancerous PK15 kidney cells. Food Chem Toxicol 44: 1758-1767, 2006.
    • (2006) Food Chem Toxicol , vol.44 , pp. 1758-1767
    • Jo, J.Y.1    de Mejia, E.G.2    Lila, M.A.3
  • 45
    • 33846624336 scopus 로고    scopus 로고
    • Protective effect of Mangifera indica L. polyphenols on human T lymphocytes against activation-induced cell death
    • Hernandez P, Rodriguez PC, Delgado R and Walczak H: Protective effect of Mangifera indica L. polyphenols on human T lymphocytes against activation-induced cell death. Pharmacol Res 55: 167-173, 2007.
    • (2007) Pharmacol Res , vol.55 , pp. 167-173
    • Hernandez, P.1    Rodriguez, P.C.2    Delgado, R.3    Walczak, H.4
  • 46
    • 34250324303 scopus 로고    scopus 로고
    • Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress
    • Feng R, Ni HM, Wang SY, Tourkova IL, Shurin MR, Harada H and Yin XM: Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. J Biol Chem 282: 13468-13476, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 13468-13476
    • Feng, R.1    Ni, H.M.2    Wang, S.Y.3    Tourkova, I.L.4    Shurin, M.R.5    Harada, H.6    Yin, X.M.7
  • 47
    • 33845612815 scopus 로고    scopus 로고
    • Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice
    • Khan N, Hadi N, Afaq F, Syed DN, Kweon MH and Mukhtar H: Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. Carcinogenesis 28: 163-173, 2007.
    • (2007) Carcinogenesis , vol.28 , pp. 163-173
    • Khan, N.1    Hadi, N.2    Afaq, F.3    Syed, D.N.4    Kweon, M.H.5    Mukhtar, H.6
  • 48
    • 0037409044 scopus 로고    scopus 로고
    • Flavonoid effects on normal and leukemic cells
    • Liesveld JL, Abboud CN, Lu C, et al: Flavonoid effects on normal and leukemic cells. Leuk Res 27: 517-527, 2003.
    • (2003) Leuk Res , vol.27 , pp. 517-527
    • Liesveld, J.L.1    Abboud, C.N.2    Lu, C.3
  • 49
    • 1842607100 scopus 로고    scopus 로고
    • Selective cytotoxicity of a red grape wine flavonoid fraction against MCF-7 cells
    • Hakimuddin F, Paliyath G and Meckling K: Selective cytotoxicity of a red grape wine flavonoid fraction against MCF-7 cells. Breast Cancer Res Treat 85: 65-79, 2004.
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 65-79
    • Hakimuddin, F.1    Paliyath, G.2    Meckling, K.3
  • 50
    • 35848940716 scopus 로고    scopus 로고
    • Comparative antioxidant and cytotoxic effect of procyanidin fractions from grape and pine
    • Ugartondo V, Mitjans M, Tourino S, Torres JL and Vinardell MP: Comparative antioxidant and cytotoxic effect of procyanidin fractions from grape and pine. Chem Res Toxicol 20: 1543-1548, 2007.
    • (2007) Chem Res Toxicol , vol.20 , pp. 1543-1548
    • Ugartondo, V.1    Mitjans, M.2    Tourino, S.3    Torres, J.L.4    Vinardell, M.P.5
  • 51
    • 40949084715 scopus 로고    scopus 로고
    • Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3
    • Miura T, Chiba M, Kasai K, et al: Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3. Carcinogenesis 29: 585-593, 2008.
    • (2008) Carcinogenesis , vol.29 , pp. 585-593
    • Miura, T.1    Chiba, M.2    Kasai, K.3
  • 54
    • 34247149508 scopus 로고    scopus 로고
    • Inhibition of cancer cell proliferation and suppression of TNF-induced activation of NFkappaB by edible berry juice
    • Boivin D, Blanchette M, Barrette S, Moghrabi A and Beliveau R: Inhibition of cancer cell proliferation and suppression of TNF-induced activation of NFkappaB by edible berry juice. Anticancer Res 27: 937-948, 2007.
    • (2007) Anticancer Res , vol.27 , pp. 937-948
    • Boivin, D.1    Blanchette, M.2    Barrette, S.3    Moghrabi, A.4    Beliveau, R.5
  • 55
    • 0036371158 scopus 로고    scopus 로고
    • p21WAF1 control of epithelial cell cycle and cell fate
    • Weinberg WC and Denning MF: p21WAF1 control of epithelial cell cycle and cell fate. Crit Rev Oral Biol Med 13: 453-464, 2002.
    • (2002) Crit Rev Oral Biol Med , vol.13 , pp. 453-464
    • Weinberg, W.C.1    Denning, M.F.2


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