The preparation and in vitro antiproliferative activity of phthalimide based ketones on MDAMB-231 and SKHep-1 human carcinoma cell lines

European Journal of Medicinal Chemistry

Volumn 44, Issue 6, 2009, Pages 2736-2740

  Chan, Sau Hing ^a   Lam, Kim Hung ^a   Chui, Chung Hin ^a,b   Gambari, Roberto ^c   Yuen, Marcus Chun Wah ^a   Wong, Raymond Siu Ming ^b   Cheng, Gregory Yin Ming ^b   Lau, Fung Yi ^b   Au, Yiu Kwok ^a   Cheng, Chor Hing ^a   Lai, Paul Bo Shan ^b   Kan, Chi Wai ^a   Kok, Stanton Hon Lung ^a   Tang, Johnny Cheuk On ^a   Chan, Albert Sun Chi ^a  

^a State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF FERRARA   (Italy)

Author keywords

Phthalimide ketones; Anti tumor activity; Breast carcinoma; Hepatoma

Indexed keywords

2 PHTHALIMIDE 1 (4 FLUORO PHENYL)ETHANONE; 2 PHTHALIMIDE 1 BIPHENYL 4 YL ETHANONE; 2 PHTHALIMIDE 1 PHENYLETHANONE; 2 PHTHALIMIDE 1 PHENYLPROPANONE; 2 PHTHALIMIDE-1 4 TOLYLETHANONE; ALPHA PHTHALIMIDE KETONE; FLUORINE; KETONE DERIVATIVE; NAPHTHALIMIDE BENZOTHIAZOLE; PHTHALIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; HEPATOMA CELL; HUMAN; HUMAN CELL; ONE POT SYNTHESIS; POLYMERIZATION;

CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KETONES; MOLECULAR STRUCTURE; NEOPLASMS; PHTHALIMIDES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 64549104822     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.10.024     Document Type: Article

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