Current treatment for cutaneous leishmaniasis: A review

American Journal of Therapeutics

Volumn 16, Issue 2, 2009, Pages 178-182

  Palumbo, Emilio ^a,b  

^a Hospital of Sondrio   (Italy)

^b Emilio Palumbo   (Italy)

Author keywords

Cutaneous leishmaniasis; Paromomycin; Pentavalent antimonials; Treatment

Indexed keywords

ALLOPURINOL; AMPHOTERICIN B; ASCORBIC ACID; FLUCONAZOLE; IMIDAZOLE; ITRACONAZOLE; KETOCONAZOLE; MEGLUMINE ANTIMONATE; METHYLBENZETHONIUM CHLORIDE; N ACETYL S NITROSOPENICILLAMINE; NITRITE; PAROMOMYCIN; PENTAMIDINE; STIBOGLUCONATE SODIUM;

ADVERSE DRUG REACTION; ALLERGIC REACTION; ANAPHYLAXIS; ANEMIA; BONE MARROW SUPPRESSION; BRONCHOSPASM; CONFUSION; COUGHING; DEPRESSION; DIARRHEA; DISEASE ASSOCIATION; DIZZINESS; DRUG INHIBITION; FATIGUE; GASTROINTESTINAL SYMPTOM; HAIR LOSS; HALLUCINATION; HEADACHE; HEART ARRHYTHMIA; HEPATITIS; HUMAN; HYPERPYREXIA; HYPOKALEMIA; HYPOTENSION; KIDNEY TUBULE DISORDER; LEUKOPENIA; LIVER TOXICITY; MALAISE; MOTION SICKNESS; MYALGIA; NAUSEA; NEPHROTOXICITY; NEURALGIA; PANCREATITIS; PRIORITY JOURNAL; PRURITUS; QT PROLONGATION; RASH; REVIEW; SIDE EFFECT; SKIN LEISHMANIASIS; STOMACH DISCOMFORT; STOMACH PAIN; SWELLING; THROMBOCYTOPENIA; THROMBOPHLEBITIS; TREATMENT DURATION; TREATMENT OUTCOME; UREMIA; VOMITING; ZOONOSIS;

ADMINISTRATION, TOPICAL; ANIMALS; ANTIPROTOZOAL AGENTS; HUMANS; INSECT BITES AND STINGS; LEISHMANIA; LEISHMANIASIS, CUTANEOUS; PSYCHODIDAE; ZOONOSES;

EID: 64549094687     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e3181822e90     Document Type: Review

References (21)

1. Herwaldt BL. Leishmaniasis. Lancet. 1999;354:1191-1199.
2. Hyams KC, Hanson K, Wignall FS, et al. The impact of infectious diseases on the health of U.S. troops deployed to the Persian Gulf during operations Desert Shield and Desert Storm. Clin Infect Dis. 1995;20:1497-1504.
3. Desjeux, P. Worldwide increasing risk factors for leishmaniasis. Med Microbiol Immunol. 2001;190:77-79.
4. Murray HW, Berman J, Davies CR, et al. Advances in leishmaniasis. Lancet. 2005;366:1561-1577.
5. Blum J, Desjeux P, Schwartz E, et al. Treatment of cutaneous leishmaniasis among travellers. J Antimicrob Chemother. 2004;53:158-166.
6. Herwaldt B, Berman D. Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am } Trop Med Hyg. 1992;46:296-306.
7. Esfandiarpour I, Alavi A. Evaluating the efficacy of allopurinol and meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis. Int ] Dermatol. 2002;41:521-524.
8. Wortmann G, Miller RS, Oster C, et al. A randomized, double-blind study of the efficacy of a 10-or 20-day course of sodium stibogluconate for treatment of cutaneous leishmaniasis in United States military personnel. Clin Infect Dis. 2002;35:261-267.
9. Nacher M, Carme B, Sainte MD, et al. Influence of clinical presentation on the efficacy of a short course of pentamidine in the treatment of cutaneous leishmaniasis in French Guiana. Ann Trop Med Parasitol. 2001;95:331-336.
10. Pradinaud R. Le traitement de la leishmaniose tegumen-taire par la pentamidine en Guyane Franpaise. Med Tropicale. 1994;54:418-422.
11. Soto J, Buffet P, Grogl M, et al. Successful treatment of Colombian cutaneous leishmaniasis with four injections of pentamidine. Am J Trop Med Hyg. 1994;50:107-111.
12. Amato V, Amato J, Nicodemo A, et al. Treatment of mucocutaneous leishmaniasis with pentamidine isothio-nate. Ann Dermatol Venereol. 1998;125:492-495.
13. Soto-Mancipe J, Grogl M, Berman JD. Evaluation of pentamidine for the treatment of cutaneous leishmaniasis in Colombia. Clin Infect Dis. 1993;16:417-425.
14. Alrajhi AA, Ibrahim EA, De Vol EB, et al. Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major. N Engl J Med. 2002;346:891-895.
15. Soto J, Toledo J, Gutierrez P, et al. Treatment of Americancutaneous leishmaniasis with miltefosine, an oral agent. Clin Infect Dis. 2001;33:57-61.
16. D'Oliveira JA, Machado PR, Carvalho EM. Evaluating the efficacy of allopurinol for the treatment of cutaneous leishmaniasis. Int J Dermatol. 1997;36:938-940.
17. Gurei MS, Tatli N, Ozbilge H, et al. Efficacy of cryotherapy and intralesional pentostam in treatment of cutaneous leishmaniasis. J Egypt Soc Parasitol. 2000;30: 169-176.
18. Bryceson AD, Murphy A, Moody AH. Treatment of 'Old World' cutaneous leishmaniasis with aminosidine ointment: results of an open study in London. Trans R Soc Trop Med Hyg. 1994;88:226-228.
19. Arana BA, Mendoza CE, Rizzo NR, et al. Randomized, controlled, double-blind trial of topical treatment of cutaneous leishmaniasis with paromomycin plus meth-ylbenzethonium chloride ointment in Guatemala. Am J Trop Med Hyg. 2001;65:466-470.
20. Krause G, Kroeger A. Topical treatment of American cutaneous leishmaniasis with paramomycin and methyl-benzethonium chloride: a clinical study under field conditions in Ecuador. Trans R Soc Trop Med Hyg. 1994;88:92-94.
21. Faghihi G, Tavakoli-Kia R. Treatment of cutaneous leishmaniasis with either topical paramomycin or intra-lesional meglumine antimoniate. Clin Exp Dermatol. 2003; 28:13-16.