Inhibition of salivary amylase activity by cigarette smoke aldehydes

Journal of Physiology and Pharmacology

Volumn 59, Issue SUPPL. 6, 2008, Pages 727-737

  Weiner, D ^a   Levy, Y ^a   Khankin, E V ^b   Reznick, A Z ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

amylase; Aldehydes; Cigarette smoke, glutathione, ; SH groups

Indexed keywords

ALDEHYDE; AMYLASE; CIGARETTE SMOKE; GLUTATHIONE; THIOL; ANTIDOTE;

AMYLASE BLOOD LEVEL; ARTICLE; CHEMICAL REACTION; CHEMOLUMINESCENCE; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; MALE; MICHAEL ADDITION; NORMAL HUMAN; SALIVARY GLAND; SALIVATION; ADULT; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; ISOLATION AND PURIFICATION; LUMINESCENCE; SALIVA; SMOKE; TOBACCO;

ADULT; ALDEHYDES; ALPHA-AMYLASES; ANTIDOTES; FEMALE; GLUTATHIONE; HUMANS; LUMINESCENCE; MALE; SALIVA; SMOKE; TOBACCO;

EID: 64549091014     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Salaspuro VJ, Hietala JM, Marvola ML, Salaspuro MP. Eliminating Carcinogenic Acetaldehyde By Cysteine From Saliva During Smoking. Cancer Epidemiol Biomarkers Prev 2006; 15: 146-149.
2. Anonymous. Tobacco smoking and involuntary smoking. IARC monographs on the evaluation of carcinogenic risk of chemicals to humans. 83. Lyon (France): IARC; 2004.
3. Sasco AJ, Secretan MB, Straif K. Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer 2004; 45 Suppl: 53-59.
4. Nagler R, Lischinsky S, Diamond E, Drigues N, Klein I, Reznick AZ. Effect of cigarette smoke on salivary proteins and enzyme activities. Arch Biochem Biophys 2000; 379: 229-236.
5. O'Neill CA, Halliwell B, Van der Vliet A et al. Aldehyde induced protein modification in human plasma: Protection by glutathione and dihydrolipoic acid. J Lab Clin Med 1994; 124: 359-369.
6. Salaspuro V, Salaspuro M. Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva. Int J Cancer 2004; 111: 480-483.
7. Reznick, AZ, Cross CE, Hu ML et al. Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation. Biochem J 1992; 286: 607-611.
8. Klein I, Nagler RM, Toffler R, Van der Vliet A, Reznick AZ. Effect of cigarette smoke on oral peroxidase activity in human saliva : Role of hydrogen cyanide. Free Radic Biol Med 2003; 35: 1448-1452.
9. Nagler RM, Lischinsky S, Diamond E, Klein I, Reznick AZ. New insights into salivary lactate dehydrogenase of human subjects. J Lab Clin Med 2001; 137: 363-369.
10. Zappacosta B, Persichilli S, Mordente A et al. Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione. Hum Exp Toxicol 2002; 21: 7-11.
11. Mandel ID. The functions of saliva. J Dent Res 1987; 66: 623-627.
12. Tabak LA, Levine MJ, Mandel ID, Ellison SA. Role of salivary mucins in the production of oral cavity. J Oral Pathol 1982; 11: 1-17.
13. Moore S, Calder KA, Miller NJ, Rice-Evans CA. Antioxidant activity of saliva and periodontal disease. Free Radic Res 1994; 21: 417-425.
14. Reznick AZ, Shehadeh N, Shafir Y, Nagler RM. Free radicals related effects and antioxidants in saliva and serum of adolescents with Type 1 diabetes mellitus. Arch Oral Biol 2006; 51: 640-648.
15. Bar-Shai M, Hasnis E, Wiener-Megnazi Z, Reznick AZ. The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-KB and implication to inflammatory processes. J Physiol Pharmacol 2006; 57 Suppl 4: 39-44.
16. Pryor WA, Prier DG, Church DF. Electron spin resonance study of main mainstream and sidestream cigarette smoke: nature of the free radicals in gas-phase smoke and in cigarette tar. Environ Health Perspect 1983; 47: 345-355.
17. Hasnis E, Bar-Shai M, Burbea Z, Reznick AZ. Cigarette smoke-induced NF-κB activation in human lymphocytes: the effect of low and high exposure to gas phase of cigarette smoke. J Physiol Pharmacol 2007; 58 Suppl 5: 263-274.
18. Hasnis E, Bar-Shai M, Burbea Z, Reznick AZ. Mechanisms underlying cigarette smoke-induced NF-κB activation in human lymphocytes: the role of reactive nitrogen species. J Physiol Pharmacol 2007; 58 Suppl 5: 275-288.