A highly sensitive and selective diagnostic assay based on virus nanoparticles

Nature Nanotechnology

Volumn 4, Issue 4, 2009, Pages 259-264

  Park, Jin Seung ^a   Cho, Moon Kyu ^a   Lee, Eun Jung ^a   Ahn, Keum Young ^a   Lee, Kyung Eun ^a   Jung, Jae Hun ^b   Cho, Yunjung ^c   Han, Sung Sik ^a   Kim, Young Keun ^a   Lee, Jeewon ^a  

^a Korea University   (South Korea)

^b Hallym University Medical Center   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BODY FLUIDS; DIAGNOSIS; ENZYMES; NANOMETALS; NANOPARTICLES; NICKEL; VIRUSES;

ACUTE MYOCARDIAL INFARCTION; DETECTION SENSITIVITY; DIAGNOSTIC ASSAYS; ENZYME LINKED IMMUNOSORBENT ASSAY; ORDERS OF MAGNITUDE; SELECTIVE DIAGNOSTICS; THREE-DIMENSIONAL NANOSTRUCTURES; VIRAL NANOPARTICLES;

CHEMICAL DETECTION;

ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; NANOPARTICLE; NICKEL; QUANTUM DOT; TROPONIN I; UNCLASSIFIED DRUG; VIRUS NANOPARTICLE;

ACUTE HEART INFARCTION; ARTICLE; BIOSENSOR; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; PHOTOLUMINESCENCE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; SENSITIVITY AND SPECIFICITY; SERUM; TRANSMISSION ELECTRON MICROSCOPY; VIRUS CAPSID; VIRUS LIKE AGENT;

EID: 64449087577     PISSN: 17483387     EISSN: 17483395     Source Type: Journal    
DOI: 10.1038/nnano.2009.38     Document Type: Article

References (29)

1. Adams, J. E. et al. Cardiac troponin I. A marker with high specificity for cardiac injury. Circulation 88, 101-106 (1993).
2. Adams, J. E., Schechtman, K. B., Landt, Y., Ladenson, J. H. & Jaffe, A. S. Comparable detection of acute myocardial infarction by creatine kinase MB isoenzyme and cardiac troponin I. Clin. Chem. 40, 1291-1295 (1994).
3. Thygesen, K., Alpert, J. S. & White, H. D. Universal definition of myocardial infarction. J. Am. Coll. Cardiol. 50, 2173-2195 (2007).
4. Morrow, D. A. et al. National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Clin. Chem. 53, 552-574 (2007).
5. Gibler, W. B. et al. Practical implementation of the guidelines for unstable angina/non-ST-segment elevation myocardial infarction in the emergency department. Ann. Emerg. Med. 46, 185-197 (2005).
6. Antman, E. M. et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N. Engl. J. Med. 335, 1342-1349 (1996).
7. Wu, A. H. B. & Jaffe, A. S. The clinical need for high-sensitivity cardiac troponin assays for acute coronary syndromes and the role for serial testing. Am. Heart J.155, 208-214 (2008).
8. Benamer, H. et al. Elevated cardiac troponin I predicts a high-risk angiographic anatomy of the culprit lesion in unstable angina. Am. Heart J. 137,815-820 (1999).
9. Heeschen, C, van den Brand, M. J., Hamm, C. W. & Simoons, M. L. Angiographic findings in patients with refractory unstable angina according to troponin T status. Circulation 100, 1509-1514 (1999).
10. Wong, G. C. et al. Elevations in troponin T and I are associated with abnormal tissue level perfusion: A TACTICS-TIMI 18 substudy Circulation 106, 202-207 (2002).
11. Rosi, N. L. & Mirkin, C. A. Nanostructures in biodiagnostics. Chem. Rev. 105, 1547-1562 (2005).
12. Hirsch, L. R., Jackson, J. B., Lee, A., Halas, N. J. & West, J. A whole blood immunoassay using gold nanoshells. Anal. Chem. 75, 2377-2381 (2003).
13. Nam, J. M., Park, S. J. & Mirkin, C. A. Bio-barcodes based on oligonucleotide- modified nanoparticles. J. Am. Chem. Soc. 124, 3820-3821 (2002).
14. Niemeyer, C. M. & Ceyhan, B. DNA-directed functionalization of colloidal gold with proteins. Angew. Chem. Int. Ed. 40, 3685-3688 (2001).
15. Chien, R. J. et al. Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proc. Natl Acad. Sci. 100, 4984-4989 (2003).
16. Wang, J., Polsky, R., Merkoci, A. & Turner, K. L. DNA-based amplified bioelectronic detection and coding of proteins. Angew. Chem. Int. Ed. 43, 2158-2161 (2004).
17. Rowe, C. A. et al. Array biosensor for simultaneous identification of bacterial, viral and protein analytes. Anal. Chem. 71, 3846-3852 (1999).
18. Gouda, H. et al. NMR study of the interaction between the B domain of staphylococcal protein A and the Fc portion of immunoglobulin G. Biochemistry37,129-136(1998).
19. Deisenhofer, J. Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A. resolution. Biochemistry 20, 2361-2370 (1981).
20. Bottcher, B., Wynne, S. A. & Crowther, R. A. Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy Nature 386,88-91 (1997).
21. Crowther, R. A. et al. Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy. Cell 77, 943-950 (1994).
22. Fischlechner, M. & Donath, E. Viruses as building blocks for materials and devices. Angew Chem. Int. Ed. 46, 3184-3193 (2007).
23. Toellner, L., Fischlechner, M., Ferko, B., Grabherr, R. M. & Donath, E. Virus-coated layer-by-layer colloids as a multiplex suspension array for the detection and quantification of virus-specific antibodies. Clin. Chem. 52,1575-1583 (2006).
24. Yang, L. M. C. et al. Virus electrodes for universal biodetection. Anal. Chem. 78, 3265-3270 (2006).
25. Willis, S. et al. Virus-like particles as quantitative probes of membrane protein interactions. Biochemistry 47, 6988-6990 (2008).
26. Datta, M. et al. High relaxivity gadolinium hydroxypyridonate- viral capsid conjugates: nanosized MRI contrast agents. J. Am. Chem. Soc. 130, 2546-2552 (2008).
27. Fischlechner, M. et al. Fusion of enveloped virus nanoparticles with polyelectrolyte-supported lipid membranes for the design of bio/nonbio interfaces. Nano Lett. 7, 3540-3546 (2007).
28. Apple, F. S., Smith, S. W., Pearce, L. A., Ler, R. & Murakami, M. M. Use of the centaur Tnl-ultra assay for detection of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. Clin. Chem. 54, 723-728 (2008).
29. Ahn, J. Y. et al. Heterologous gene expression using self-assembled supra- molecules with high affinity for HSP70 chaperone. Nucl. Acids Res. 33, 3751-3762 (2005).