A novel mechanism: Erxian Decoction, a Chinese medicine formula, for relieving menopausal syndrome

Journal of Ethnopharmacology

Volumn 123, Issue 1, 2009, Pages 27-33

  Sze, S C W ^a   Tong, Y ^a   Zhang, Y B ^a   Zhang, Z J ^a   Lau, A S L ^b   Wong, H K ^a   Tsang, K W ^a   Ng, T B ^c  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Antioxidant; Chinese medicine; Endocrine function; Erxian Decoction; Menopause

Indexed keywords

ANTIOXIDANT; AROMATASE; BERBERINE; BETA ACTIN; CATALASE; CHINESE DRUG; CONJUGATED ESTROGEN; COPPER ZINC SUPEROXIDE DISMUTASE; ERXIAN; ESTRADIOL; FERULIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; ICARIIN; JATORRHIZINE; LIVER ENZYME; MESSENGER RNA; PALMATINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG EFFECT; ENDOCRINE FUNCTION; ENZYME ACTIVITY; ESTRADIOL BLOOD LEVEL; ESTROGEN METABOLISM; ESTROGEN SYNTHESIS; FEMALE; MENOPAUSAL SYNDROME; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; TREATMENT DURATION;

AGING; ANIMALS; AROMATASE; BASE SEQUENCE; CATALASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; DRUGS, CHINESE HERBAL; ESTRADIOL; FEMALE; GLUTATHIONE PEROXIDASE; LIVER; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEXUAL MATURATION; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 64449086729     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.02.034     Document Type: Article

References (47)

1. Ban Z.A., and S X. Pharmacopoeia of the People's Republic of China (2005), Beijing Chemical Industry Press pp. 66, 229, 289, 255, 214, 148
2. Barone E., Calabrese V., and Mancuso C. Ferulic acid and its therapeutic potential as a hormetin for age-related diseases. Biogerontology 10 (2009) 97-108
3. Burger H., Woods N.F., Dennerstein L., Alexander J.L., Kotz K., and Richardson G. Nomenclature and endocrinology of menopause and perimenopause. Expert Review of Neurotherapeutics 7 (2007) S35-43
4. Chattopadhyay S., Ghosh S., Chaki S., Debnath J., and Ghosh D. Effect of sodium arsenite on plasma levels of gonadotrophins and ovarian steroidogenesis in mature albino rats: duration-dependent response. Journal of Toxicological Sciences 24 (1999) 425-431
5. Chen H.Y., Cho W.C.S., Sze S.C.W., and Tong Y. Treatment of menopausal symptoms with Er-xian decoction: a systematic review. Amercian Journal of Chinese Medicine 36 (2008) 233-244
6. Chi Y.W.C.S., Yang M.H., Hwang R.C., and Chu F.M.L. Heavy metals in traditional Chinese medicine: Ba-pao-neu-hwang-san. Acta Paediatrica Sinica 34 (1993) 181-190
7. Danilovich N., Javeshghani D., Xing W.R., and Sairam M.R. Endocrine alterations and signaling changes associated with declining ovarian function and advanced biological aging in follicle-stimulating hormone receptor haploinsufficient mice. Biology of Reproduction 67 (2002) 370-378
8. Danilovich N., and Sairam M.R. Recent female mouse models displaying advanced reproductive aging. Experimental Gerontology 41 (2006) 117-122
9. Diamanti-Kandarakis E. Hormone replacement therapy and risk of malignancy. Current Opinion in Obstetrics & Gynecology 16 (2004) 73-78
10. Dong B.F., Fang Z.Q., and Shi J.R. Effect of er xian decoction and its subdivisions on granulosa cells secretory function in rats. Chinese Journal of Integrative Medicine 26 Supplement (2006) 122-125
11. Droge W. Free radicals in the physiological control of cell function. Physiological Reviews 82 (2002) 47-95
12. Droge W. Oxidative stress and aging. Advances in Experimental Medicine and Biology 543 (2003) 191-200
13. Droge W., and Schipper H.M. Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6 (2007) 361-370
14. Dong B.F., and Fang Z.Q. The progress on experimental research of Erxian Decoction. Chinese Journal of Basic Medicine in Traditional Chinese Medicine 9 (2003) 78-81
15. Fang Z.Q., Xu P.C., and Zhang B.N. Effect of Erxian Decoction and its subdivisions on sexual hormone secretory function in rats. China Journal of Traditional Chinese Medicine and Pharmacy 7 (1992) 24-26
16. Fortepiani L.A., Zhang H., Racusen L.C., Roberts II L.J., and Reckelhoff J.F. Characterization of an animal model of postmenopausal hypertension in SHR. Hypertension 41 (2003) 640-645
17. Ji L.L., Stratman F.W., and Lardy H.A. Antioxidant enzyme systems in rat liver and skeletal muscle. Influences of selenium deficiency, chronic training, and acute exercise. Archives of Biochemistry and Biophysics 263 (1988) 150-160
18. Kamiyama H., Hirato K., Akamatsu T., Saitoh H., Yanaihara T., and Kushima M. Changes in steroid enzyme activities with age in human ovary. Nippon Sanka Fujinka Gakkai Zasshi 44 (1992) 419-426
19. Kim J.P., Jung M.Y., Kim J.P., and Kim S.Y. Antiphotooxidative activity of protoberberines derived from Coptis japonica makino in the chlorophyll-sensitized photooxidation of oil. Journal of Agricultural and Food Chemistry 48 (2000) 1058-1063
20. Li J.J., Li J.T., and Fu J.P. Erxian Tang-introduction of a Chinese herbal formula, clinical practice, and experimental studies. Chinese Journal of Integrative Medicine 13 (2007) 67-73
21. Li H., Miyahara T., Tezuka Y., Tran Q.L., Seto H., and Kadota S. Effect of berberine on bone mineral density in SAMP6 as a senile osteoporosis model. Biological & Pharmaceutical Bulletin 26 (2003) 110-111
22. Liu Z.Q., Luo X.Y., Sun Y.X., Wu W., Liu C.M., Liu Z.Q., and Liu S.Y. The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis. Journal of Pharmacy and Pharmacology 56 (2004) 1557-1562
23. Low Dog T. Menopause: a review of botanical dietary supplements. American Journal of Medicine 118 (2005) 98-108
24. Lucia R., Magdale M., Daniela K., and Milan S. Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium structural aspects. Bioorganic and Medicinal Chemistry 12 (2004) 4709-4715
25. Nagata C., Nagao Y., Shibuya C., Kashiki Y., and Shimizu H. Urinary cadmium and serum levels of estrogens and androgens in postmenopausal Japanese women. Cancer Epidemiology Biomarkers & Prevention 14 (2005) 705-708
26. Newton K.M., Buist D.S.M., Keenan N.L., Anderson L.A., and LaCroix A.Z. Use of alternative therapies for menopause symptoms: results of a population-based survey. Obstetrics and Gynecology 100 (2002) 18-25
27. Nian H., Qin L.P., Zhang Q.Y., Zheng H.C., Yu Y., and Huang B.K. Antiosteoporotic activity of Er-Xian Decoction, a traditional Chinese herbal formula, in ovariectomized rats. Journal of Ethnopharmacology 108 (2006) 96-102
28. Okatani Y., Morioka N., Wakatsuki A., Nakano Y., and Sagara Y. Role of the free radical-scavenger system in aromatase-activity of the human ovary. Hormone Research 39 (1993) 22-27
29. Orr W.C., and Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263 (1994) 1128-1130
30. Philip H.A. Hot flashes-a review of the literature on alternative and complementary treatment approaches. Alternative Medicine Review 8 (2003) 284-302
31. Purohit A., and Reed M.J. Regulation of estrogen synthesis in postmenopausal women. Steroids 67 (2002) 979-983
32. Qin L., Han T., Zhang Q., Cao D., Nian H., Rahman K., and Zheng H. Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula. Journal of Ethnopharmacology 118 (2008) 271-279
33. Ray G., and Husain S.A. Oxidants, antioxidants and carcinogenesis. Indian Journal of Experimental Biology 40 (2002) 1213-1232
34. Ross R.K., Paganini-Hill A., Wan P.C., and Pike M.C. Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin. Journal of the National Cancer Institute 92 (2000) 328-332
35. Sassa S., Kikuchi T., Shinoda H., Suzuki S., Kudo H., and Sakamoto S. Preventive effect of ferulic acid on bone loss in ovariectomized rats. In Vivo 17 (2003) 277-280
36. Simpson E.R., Mahendroo M.S., Means G.D., Kilgore M.W., Hinshelwood M.M., Grahamlorence S., Amarneh B., Ito Y.J., Fisher C.R., Michael M.D., Mendelson C.R., and Bulun S.E. Aromatase cytochrome-p450, the enzyme responsible for estrogen biosynthesis. Endocrine Reviews 15 (1994) 342-355
37. Uhl K. Advancing women's health in the 21st century: applying the tools of clinical pharmacology. Clinical Pharmacology & Therapeutics 83 (2008) 3-7
38. Uno Y. [Aging phenomena of granulosa cells in the human ovary]. [Hokkaido igaku zasshi]. The Hokkaido Journal of Medical Science 62 (1987) 558-563
39. Vera P.G.C., and Rada G.G. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. Obstetrical & Gynecological Survey 57 (2002) 750-752
40. Wang C.F., Duo M.J., Chang E.E., and Yang J.Y. Essential and toxic trace elements in the Chinese medicine. Journal of Radioanalytical and Nuclear Chemistry 211 (1996) 333-347
41. WHO, 1995. WHO, Inorganic Lead: Environmental Health Criteria 165, International Programme on Chemical Safety. World Health Organization, Geneva.
42. Wu J.M., Zelinski M.B., Ingram D.K., and Ottinger M.A. Ovarian aging and menopause: current theories, hypotheses, and research models. Experimental Biology and Medicine 230 (2005) 818-828
43. Ye H.Y., and Lou Y.J. Estrogenic effects of two derivatives of icariin on human breast cancer MCF-7 cells. Phytomedicine 12 (2005) 735-741
44. Zhang B. Clinical effects of traditional Chinese medicine on 328 patients with hypertension over the course of four years. Chinese Journal of Internal Medicine 13 (1965) 501-503
45. Zhang C.Z., Wang S.X., Zhang Y., Chen J.P., and Liang X.M. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. Journal of Ethnopharmacology 98 (2005) 295-300
46. Zhang L. The samples of effective clinical cases of Er Xian Tang application by professor Wenzhen Huang. Fujian Journal of Traditional Chinese Medicine 35 (2004) 19-22
47. Zimon A., Erat A., Von Wald T., Bissell B., Koulova A., Choi C.H., Bachvarov D., Reindollar R.H., and Usheva A. Genes invoked in the ovarian transition to menopause. Nucleic Acids Research 34 (2006) 3279-3287