Temporal discordance between graft-versus-leukemia and graft-versus-host responses: A strategy for the separation of graft-versus-leukemia/graft-versus-host reactivity?

Biology of Blood and Marrow Transplantation

Volumn 10, Issue 11, 2004, Pages 743-747

  Hari, Parameswaran ^a   Logan, Brent ^a   Drobyski, William R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Allogeneic bone marrow transplantation; Donor lymphocyte infusion; Graft versus host disease; Graft versus leukemia effect

Indexed keywords

ALPHA INTERFERON; HYDROXYUREA; IMMUNOMODULATING AGENT;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD DONOR; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CORRELATION ANALYSIS; DIFFERENTIAL DIAGNOSIS; FEMALE; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HLA MATCHING; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE TRANSFUSION; LYMPHOCYTOSIS; MALE; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; NONHODGKIN LYMPHOMA; T LYMPHOCYTE; TIME PERCEPTION;

ADULT; ANIMALS; BONE MARROW TRANSPLANTATION; FEMALE; GRAFT VS HOST DISEASE; GRAFT VS LEUKEMIA EFFECT; HUMANS; LEUKEMIA; LYMPHOCYTE TRANSFUSION; MALE; MICE; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 6444236370     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbmt.2004.07.006     Document Type: Article

References (20)

1. R.L. Truitt B.D. Johnson Principles of graft versus leukemia reactivity Biol Blood Marrow Transplant 1 1995 61-68
2. K.M. Sullivan P.L. Weiden R. Storb et al. Influence of acute and chronic graft versus host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia Blood 73 1989 1720-1728
3. M.M. Horowitz R.P. Gale P.M. Sondel et al. Graft-versus-leukemia reactions after bone marrow transplantation Blood 75 1990 555-562
4. T.R. Truitt C.Y. Shih A.V. LeFever L.D. Tempelis M. Andeani M.M. Bortin Characterization of alloimmunization-induced T lymphocytes reactive against AKR leukemia in vitro and correlation with graft versus leukemia activity in vitro J Immunol 131 1983 2050-2058
5. J.H. Falkenburg A.R. Wafelman P. Joosten et al. Complete remission of accelerated phase chronic myeloid leukemia by treatment with leukemia-reactive cytotoxic T lymphocytes Blood 94 1999 1201-1208
6. K. Rezvani M. Grube J.M. Brenchley et al. Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation Blood 102 2003 2892-2900
7. F.M. Kloosterboer S.A. Van Luxemburg-Heijs R.V. Soest et al. Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 specific T cells Leukemia 18 2004 798-808
8. T. Mutis R. Verdijk E. Schrama B. Esendam A. Brand E. Goulmy Feasibility of immunotherapy of relapsed leukemia with ex vivo generated cytotoxic T lymphocytes specific for hematopoietic system-restricted minor histocompatibility antigens Blood 93 1999 2336-2341
9. D. Bonnet E.H. Warren P.D. Greenberg J.E. Dick S.R. Riddell CD8 (+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells Proc Natl Acad Sci U S A 96 1999 8639-8644
10. W.A. Marjit M.H. Heemskerk F.M. Kloosterboer et al. Hematopoiesis-restricted minor histocompatibility antigens HA-1 or HA-2-specific T cells can induce complete remissions of relapsed leukemia Proc Natl Acad Sci U S A 100 2003 2742-2747
11. J. Michalek R.H. Collins H.P. Durrani et al. Definitive separation of graft versus leukemia and graft versus host specific CD+ T cells by virtue of their receptor beta loci sequences Proc Natl Acad Sci U S A 100 2003 1180-1184
12. T. Crough M. Nieda J. Morton J. Bashford S. Durrant A.J. Nicol Donor-derived b2a2-specific T cells for immunotherapy of patients with chronic myeloid leukemia J Immunother 25 2002 469-475
13. M. Boranic I. Tonkovic Time pattern of the antileukemic effect of graft-versus-host reaction in mice Cancer Res 31 1971 1140-1147
14. W.R. Drobyski M. Gendelman Vodanovic-Jankovic J. Gorski Elimination of leukemia in the absence of lethal graft versus host disease J Immunol 170 2003 3046-3053
15. R.K. Burt W. Drobyski T Seregina et al. Herpes simplex thymidine kinase gene transduced donor lymphocyte infusions for relapsed hematologic malignancies following allogeneic hematopoietic stem cell transplantation Exp Hematol 31 2003 903-910
16. M.J. Hessner M.S. Roth W.R. Drobyski L.A. Baxter-Lowe Development of a sensitive, highly controlled assay for molecular detection of the Philadelphia chromosome in patients with chronic myelogenous leukemia Genet Anal Tech Appl 11 1994 90-94
17. C.J. Link R.K. Burt A.E. Traynor W.R. Drobyski Adoptive immunotherapy for leukemia donor lymphocytes transduced with the herpes thymidine kinase gene for remission induction Hum Gene Ther 9 1998 115-134
18. C. Bonini G. Ferrari S. Verzeletti et al. HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia Science 276 1997 1719-1724
19. C. Berger C.A. Blau M.L. Huang et al. Pharmacologically regulated fas-mediated death of adoptively transferred T cells in a nonhuman primate model Blood 103 2003 1261-1269
20. D.C. Thomis S. Marktel C. Bonini et al. A fas-based suicide switch in human T cells for the treatment of graft versus host disease Blood 97 2001 1249-1257