Safety of an Immunosuppressant Protocol Based on Sirolimus in Liver Transplant Recipients With Malignancies or High Risk of Tumor Recurrence

Transplantation Proceedings

Volumn 41, Issue 3, 2009, Pages 1003-1004

  Castroagudin J F ^a   Molina, E ^a   Tome S ^a   Otero, E ^a   Rodriguez M ^a   Varo, E ^a  

^a University Hospital of Santiago de Compostela   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; RAPAMYCIN; SORAFENIB;

ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; CANCER RECURRENCE; CANCER RISK; CLINICAL ARTICLE; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DYSFUNCTION; LIVER CANCER; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MALE; MOUTH ULCER; PRIORITY JOURNAL; SIDE EFFECT; VASCULAR DISEASE;

ADULT; CALCINEURIN; CARCINOMA, HEPATOCELLULAR; DRUG TOLERANCE; FOLLOW-UP STUDIES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER NEOPLASMS; MIDDLE AGED; RECURRENCE; SAFETY; SIROLIMUS; SURVIVAL RATE; SURVIVORS;

EID: 64349110801     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.02.017     Document Type: Article

References (6)

1. Guba M., Graeb C., Jauch K.W., et al. Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation. Transplantation 77 (2004) 1777
2. Sieghart W., Fuereder T., Schmid K., et al. Mammalian target of rapamycin pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation. Transplantation 83 (2007) 425
3. Campistol J.M., Eris J., Oberbauer R., et al. Sirolimus therapy after early cyclosporine withdrawal reduces the risk of cancer in adult renal transplantation. J Am Soc Nephrol 17 (2006) 581
4. Kauffman H.M., Cherikh W.S., Cheng Y., et al. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 80 (2005) 883
5. Zimmerman M.A., Trotter J.F., Wachs M., et al. Sirolimus-based immunosupression following liver transplantation for hepatocellular carcinoma. Liver Transpl 14 (2008) 633
6. Nocera A., Andorno E., Tagliamacco A., et al. Sirolimus therapy in liver transplant patients: an initial experience at a single center. Transplant Proc 40 (2008) 1950