Valganciclovir-Induced Leukopenia in Liver Transplant Recipients: Influence of Concomitant Use of Mycophenolate Mofetil

Transplantation Proceedings

Volumn 41, Issue 3, 2009, Pages 1047-1049

  Molina Perez, E ^a   Fernandez Castroagudin J ^a   Seijo Rios S ^a   Mera Calvino J ^a   Tome Martinez de Rituerto S ^a   Otero Anton E ^a   Bustamante Montalvo, M ^a   Varo Perez, E ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; VALGANCICLOVIR;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE SEVERITY; FEMALE; HUMAN; INCIDENCE; LEUKOCYTE COUNT; LEUKOPENIA; LIVER GRAFT; MALE; NEUTROPENIA; NEUTROPHIL COUNT; PRIORITY JOURNAL; SCORING SYSTEM;

ADULT; ANTIVIRAL AGENTS; BODY MASS INDEX; CREATININE; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GANCICLOVIR; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INCIDENCE; LEUKOCYTE COUNT; LEUKOPENIA; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; NEUTROPENIA; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 64349104728     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.02.033     Document Type: Article

References (7)

1. Pescovitz M.D., Rabkin J., Merion R.M., et al. Valganciclovir results in improved oral absortion of ganciclovir in liver transplant recipients. Antimicrob Agents Chemother 44 (2000) 2811
2. Gabardi S., Magee Cc., Baroletti S.A., et al. Efficacy and safety of low-dose valganciclovir for prevention of cytomegalovirus disease in renal transplant recipients: a single-center, retrospective analysis. Pharmacotherapy 24 (2004) 1323
3. Takami A., Mochizuki K., Okumura H., et al. Mycophenolate mofetil is effective and well tolerated in the treatment of refractory acute and chronic graft-versus.host disease. Int J Hematol 83 (2006) 80
4. Nogueras F., Espinosa A., Mansilla J.T., et al. Mycophenolate mofetil-induced neutropenia in liver transplantation. Transplant Proc 37 (2005) 1509
5. Chen I.M., Chang H.-H., Hsu C.-P., et al. Correlation between body mass index and leucopenia after administration of valganciclovir for cytomegalovirus infection in Chinese cardiac recipients. Circ J 71 (2007) 968
6. Brum S., Nolasco F., Sousa J., et al. Leukopenia in kidney transplant patients with the association of valganciclovir and mycophenolate mofetil. Transplant Proc 40 (2008) 752
7. Roger B., Zanetta G., B'erard M., et al. A neutropenia suggesting an interaction between valacyclovir and mycophenolate mofetil. Clin Transplant 17 (2003) 158