Anti-CD30 human IL-2 fusion proteins display strong and specific cytotoxicity In Vivo

Current Drug Targets

Volumn 10, Issue 2, 2009, Pages 110-117

  Hirsch, B ^a   Brauer, J ^a   Fischdick, M ^a   Loddenkemper, C ^a   Bulfone Paus, S ^b   Stein, H ^a   Dürkop, Horst ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

CD30; Fusion protein; IL 2; Immunotherapy; Lymphoma

Indexed keywords

CD30 ANTIBODY INTERLEUKIN 2 FUSION PROTEIN; HYBRID PROTEIN; UNCLASSIFIED DRUG; CD30 ANTIGEN; INTERLEUKIN 2; MONOCLONAL ANTIBODY;

ANTINEOPLASTIC ACTIVITY; BAGG ALBINO MOUSE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG PURIFICATION; DRUG RESPONSE; DRUG TARGETING; HUMAN; IMMUNOCOMPETENCE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; REVIEW; SOLID TUMOR; ANIMAL; CELL SURVIVAL; DRUG DELIVERY SYSTEM; DRUG EFFECT; IMMUNOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD30; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; HUMANS; INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS;

EID: 64249159322     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009787354566     Document Type: Review

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