Does hypoxia cause sarcopenia? Prevention of hypoxia could reduce sarcopenia

Journal of Biological Regulators and Homeostatic Agents

Volumn 23, Issue 1, 2009, Pages 55-58

  Di Giulio, Camillo ^a,b   Petruccelli, G ^a,b   Bianchi, G ^a,b   Cacchio, M ^a,b   Verratti, V ^a,b  

^a UNIVERSITY OF CHIETI   (Italy)

^b Unidav Telematica Leonardo da Vinci ^*  (Italy)

Author keywords

Age; Hypoxia; Mitochondria; Sarcopenia; Volume density

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE;

AGING; ARTICLE; CAUSAL ATTRIBUTION; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; HYPOXEMIA; MITOCHONDRIAL VOLUME DENSITY; MORPHOMETRICS; MUSCLE ATROPHY; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN SUPPLY;

AGING; ANIMALS; ANOXIA; HUMANS; MITOCHONDRIA; MUSCLE, SKELETAL; MUSCULAR DISEASES; ORGAN SIZE; REACTIVE OXYGEN SPECIES;

EID: 64249148962     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Doherty TJ. Aging and sarcopenia. J Appl Physiol 2003; 95:1717-27.
2. Thompson LV. Skeletal muscle adaptations with age, inactivity, and therapeutic exercise. J Orthop Sports Phys Ther 2002; 32:44-57.
3. Gelfi C, Vigano A, Ripamonti M, et al. The human muscle proteome in aging. J of Proteome Research 2006; 5:1344-13.
4. Vogt M, Puntschart A, Geiser J, Zuleger C, Billeter R, Hoppeler H. Molecular adaptations - in human skeletal muscle to endurance training under simulated hypoxic conditions. J Appl Physiol 2001; 91:173-82.
5. Mishra SK, Misra V. Muscle sarcopenia: an overview. Acta Myol 2003; 22:43-7.
6. Lu T, Finkel T. Free radicals and senescence. Exp Cell Res 2008; 314:19 18-22.
7. D'Antona G, Pellegrino MA, Adami R, Rossi R, Carlizzi CN, Canepari M, Saltin B, Bottinelli R. The effect of aging and immobilization on structure and function of human skeletal muscle fibres. J Physiol 2003; 552:499-511.
8. Gunnarsson L, Tokics L, Brismar B, Hedenstiema G. Influence of age on circulation and arterial blood gases in man. Acta Anaesthesiol Scand 1996; 40: 237-43.
9. Muller FL, Song W, Jang YC, et al. Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. Am J Physiol Regul Integr Comp Physiol 2007; 293:1159-68.
10. Porter MM, Vandervoort AA, Lexell J. Aging of human muscle: structure, ftmction and adaptability. Scand J Med Sci Sports 1995; 5:129-42.
11. Fukuda Y. Changes in ventilatory response to hypoxia in the rat during growth and aging. Pflugers Arch 1992; 421:200-3.
12. Guenard H. Respiration and aging. Rev Mal Respir 1998; 15:713-21.
13. Sohal RS, Toy PL, Allen RG. Relationship between life expectancy, endogenous antioxidants and products of oxygen free radical reactions in the housefly, Musca domestica. Mech Ageing Dev 1986; 36:71-7.
14. Hoffmann MS, Singh P, Wolk R, Romero-Corral A, Raghavakaimal S, Somers VK. Microarray studies of genomic oxidative stress and cell cycle responses in obstructive sleep apnea. Antioxid Redox Signal 2007; 9:661-9.
15. Janssens JP, Pautex S, Hilleret H, Michel JP. Respiratory sleep disorders in the elderly. Rev Med Suisse Romande 2000; 120:869-79.
16. Agusti AG, Sauleda J, Miralles C, et al. Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002; 166:485-9.
17. Mader MJ, Bozkanat E. Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Resp Research 2001; 2:216-24.
18. Penninx BW, Pahor M, Cesari M, Corsi AM, Woodman RC, Bandinelli S et al. Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc 2004; 52:719-24.
19. Babcock MA, Paterson DH, Cunningham DA. Influence of ageing on aerobic parameters determined from a ramp test. Eur J Appl Physiol Occup Physiol 1992; 65:138-43.
20. Hepple RT, Hagen JL, Krause DJ. Oxidative capacity interacts with oxygen delivery to determine maximal O(2) uptake in rat skeletal muscles in situ. J Physiol 2002; 541:1003-12.
21. Wallace DC. Mitochondrial DNA variation in human evolution, degenerative disease, and aging. Am J Hum Genet 1995; 57:201-23.
22. Ferretti G. On maximal oxygen consumption in hypoxic humans. Experientia 1990; 46:1188-94.
23. Zhang, H, Bosch-Marce M, Shimoda La, SunTan Y, Wesley BJ, Gonzalez FJ, Semenza G. Mitochondrial autophagy is an HIF- 1 -dependent adaptive metabolic response to hypoxia. J Biol Chem 2008; 283:10892-903.
24. Amicarelli F, Ragnelli AM, Aimola P, et al. Age-dependent ultrastructural alterations and biochemical response of rat skeletal muscle after hypoxic or hyperoxic treatments. Biochim Biophys Acta 1999; 1453:105-14.
25. Hoppeler H, Vogt M, Weibel ER, Flück M. Response of skeletal muscle mitochondria to hypoxia. Exp Physiol 2003; 88:109-19.
26. Martinelli M, Winterhalder R, Cerretelli P, Howald H, Hoppeler H. Muscle lipofuscin content and satellite cell volume is increased after high altitude exposure in humans. Experientia 1990; 46:672-6.