Doxorubicin and mitoxantrone drug eluting beads for the treatment of experimental peritoneal carcinomatosis in colorectal cancer

International Journal of Cancer

Volumn 124, Issue 11, 2009, Pages 2701-2708

  Keese, Michael ^a   Gasimova, Lala ^a   Schwenke, Kay ^a   Yagublu, Vugar ^a   Shang, Edward ^a   Faissner, Ralf ^a   Lewis, Andrew ^b   Samel, Stefan ^c   Löhr, Matthias ^a,d  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b BIOCOMPATIBLES UK LTD   (United Kingdom)

^c Praxis für Koloproktologie und Chirurgische Endoskopie   (Germany)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Colon cancer; Drug eluting beads; Green fluorescent protein; Peritoneal carcinomatosis

Indexed keywords

DOXORUBICIN; IRINOTECAN; MITOXANTRONE; POLYVINYL ALCOHOL; SULFONIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DRUG DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; CANCER MORTALITY; CELL PROLIFERATION; COLORECTAL CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG INHIBITION; ENCAPSULATION; EXPERIMENTAL NEOPLASM; EXPERIMENTAL PERITONEAL CARCINOMATOSIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; INJECTION; INOCULATION; MOUSE; NONHUMAN; PERITONEUM CANCER; PRIORITY JOURNAL; SINGLE DRUG DOSE; TUMOR VOLUME; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; CHEMOEMBOLIZATION; COLORECTAL TUMOR; METASTASIS; METHODOLOGY; PATHOLOGY; PERITONEUM TUMOR; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CAMPTOTHECIN; CELL LINE, TUMOR; CHEMOEMBOLIZATION, THERAPEUTIC; COLORECTAL NEOPLASMS; DOXORUBICIN; FEMALE; MICE; MICE, INBRED BALB C; MITOXANTRONE; PERITONEAL NEOPLASMS;

EID: 64249148414     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24211     Document Type: Article

References (31)

1. Verwaal VJ, van Ruth S, de Bree E, van Sloothen GW, van Tinteren H, Boot H, Zoetmulder FA. Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer. J Clin Oncol 2003;21:3737-3743 (Pubitemid 46606227)
2. Sugarbaker PH. Intraperitoneal chemotherapy and cytoreductive surgery for the prevention and treatment of peritoneal carcinomatosis and sarcomatosis. Semin Surg Oncol 1998;14:254-261 (Pubitemid 28146518)
3. Sugarbaker PH. Management of peritoneal-surface malignancy: the surgeon's role. Langenbecks Arch Surg 1999;384:576-587 (Pubitemid 30020346)
4. Chu DZJ, Lang NP, Thompson C. Peritoneal carcinomatosis in nongynecologic malignancy. A prospective study of prognostic factors. Cancer 1989;63:364-367
5. Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM. Gastric adenocarcinoma: review and considerations for future directions. Ann Surg 2005;241:27-39. (Pubitemid 40044837)
6. Griffin AM, Butow PN, Coates AS, Childs AM, Ellis PM, Dunn SM, Tattersall MHN. On the receiving end V: patient perceptions of the side effects of cancer chemotherapy in 1993. Ann Oncol 1996;7:189-195
7. Samel S, Keese M, Lux A, Jesnowski R, Prosst R, Saller R, Hafner M, Sturm J, Post S, Löhr M. Peritoneal cancer treatment with CYP2B1 transfected, microencapsulated cells and ifosfamide. Cancer Gene Ther 2006;13:65-73. (Pubitemid 41816350)
8. Aliberti C, Tilli M, Benea G, Fiorentini G. Trans-arterial chemoembolization (TACE) of liver metastases from colorectal cancer using irinotecan- eluting beads: preliminary results. Anticancer Res 2006;26:3793-3795 (Pubitemid 44701461)
9. Lewis AL, Gonzalez MV, Lloyd AW, Hall B, Tang Y, Willis SL, Leppard SW, Wolfenden LC, Palmer RR, Stratford PW. DC bead: in vitro characterization of a drug-delivery device for transarterial chemoembolization. J Vasc Interv Radiol 2006;17:335-342 (Pubitemid 44341453)
10. Taylor RR, Tang Y, Gonzalez MV, Stratford PW, Lewis AL. Irinotecan drug eluting beads for use in chemoembolization: in vitro and in vivo evaluation of drug release properties. Eur J Pharm Sci 2007;30:7-14. (Pubitemid 44908921)
11. Gonzalez MV, Tang Y, Phillips GJ, Lloyd AW, Hall B, Stratford PW, Lewis AL. Doxorubicin eluting beads-2: methods for evaluating drug elution and in vitro: in vivo correlation. J Mater Sci Mater Med 2008;19:767-775
12. Hong K, Khwaja A, Liapi E, Torbenson MS, Georgiades CS, Geschwind JF. New intra-arterial drug delivery system for the treatment of liver cancer: preclinical assessment in a rabbit model of liver cancer. Clin Cancer Res 2006;12:2563-2567
13. Löhr M, Müller P, Karle P, Stange J, Mitzner S, Jesnowski R, Nizze H, Nebe B, Liebe S, Salmons B, Günzburg WH. Targeted chemotherapy by intratumor injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450. Gene Ther 1998;5:1070-1078 (Pubitemid 28401309)
14. Sturm JW, Keese MA, Petruch B, Bönninghoff RG, Zhang H, Gretz N, Hafner M, Post S, McCuskey RS. Enhanced green fluorescent protein- transfection of murine colon carcinoma cells: key for early tumor detection and quantification. Clin Exp Metastasis 2003;20:395-405. (Pubitemid 37108425)
15. National Research Council. Institute of laboratory animal resources. Commission on life sciences. Guide for the care and use of laboratory animals. Washington DC: National Academy Press, 1996.
16. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994;263:802-805 (Pubitemid 24093206)
17. Halene S, Wang L, Cooper RM, Bockstoce DC, Robbins PB, Kohn DB. Improved expression in hematopoietic and lymphoid cells in mice after transplantation of bone marrow transduced with a modified retroviral vector. Blood 1999;94:3349-3357 (Pubitemid 29536128)
18. Koizumi F, Kanzawa F, Ueda Y, Koh Y, Tsukiyama S, Taguchi F, Tamura T, Saijo N, Nishio K. Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells. Int J Cancer 2004;108:464-472 (Pubitemid 37549614)
19. Pilati P, Rossi C, Mocellin S, Foletto M, Scagnet B, Pasetto L, Lise M. Multimodal treatment of peritoneal carcinomatosis and sarcomatosis. Eur J Surg Oncol 2001;27:125-134 (Pubitemid 32621722)
20. Jacquet P, Stephens AD, Averbach AM, Chang D, Ettinghausen SE, Dalton RR, Steves MA, Sugarbaker PH. Analysis of morbidity and mortality in 60 patients with peritoneal carcinomatosis treated by cytoreductive surgery and heated intraoperative intraperitoneal chemotherapy. Cancer 1996;77:2622-2629 (Pubitemid 26169161)
21. Jacquet P, Vidal-Jove J, Zhu BW, Sugarbaker PH. Peritoneal carcinomatosis from intra abdominal malignancy: natural history and new prospects for management. Acta Chir Belg 1994;94:191-197
22. Sugarbaker PH. Review of personal experience in the management of carcinomatosis and sarcomatosis. Jpn J Clin Oncol 2001;31:573-583 (Pubitemid 34116470)
23. Varela M, Real M, Burrel A, Forner M, Sala M, Brunet C, Ayuso L, Castells X, Montañá Llovet J. Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics. J Hepatol 2007;46:474-481 (Pubitemid 46201723)
24. Colucci G, Gebbia V, Paoletti G, Giuliani F, Caruso M, Gebbia N, Cartenì G, Agostara B, Pezzella G, Manzione L, Borsellino N, Misino A, et al. Gruppo Oncologico Dell'Italia Meridionale Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005;23:4866-4875 (Pubitemid 46223991)
25. O'Dwyer PJ, Catalano RB. Uridine diphosphate glucuronosyltransferase (UGT) 1A1 and irinotecan: practical pharmacogenomics arrives in cancer therapy. J Clin Oncol 2006;24:4534-4538 (Pubitemid 46630947)
26. Momparler RL, Karon M, Siegel SE, Avila F. Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells. Cancer Res 1976;36:2891-2895
27. Caponigro F, Avallone A, Rivellini F, Comella P, Ionna F, De Rosa V, Comella G. Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours. Cancer Chemother Pharmacol 2001;47:113-116 (Pubitemid 32662315)
28. Huerta S, Goulet EJ, Huerta-Yepez S, Livingston EH. Screening and detection of apoptosis. J Surg Res 2007;139:143-156
29. Eyol E, Boleij A, Taylor RR, Lewis AL, Berger MR. Chemoembolisation of rat colorectal liver metastases with drug eluting beads loaded with irinotecan or doxorubicin. Clin Exp Metastasis 2008;25:273-282
30. van Ark-Otte J, Kedde MA, van der Vijgh WJ, Dingemans AM, Jansen WJ, Pinedo HM, Boven E, Giaccone G. Determinants of CPT-11 and SN-38 activities in human lung cancer cells. Br J Cancer 1998;77:2171-2176 (Pubitemid 28263937)
31. Reid RJ, Benedetti P, Bjornsti MA. Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs. Biochim Biophys Acta 1998;1400:289-300. (Pubitemid 28475110)