Risk of venous thromboembolism with bevacizumab in cancer patients

JAMA

Volumn 301, Issue 14, 2009, Pages 1434-1435

  Cortes, Javier ^a   Saura, Cristina ^a   Atzori, Francesco ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CYTOKINE; DOCETAXEL; PLACEBO; ANGIOGENESIS INHIBITOR; MONOCLONAL ANTIBODY;

CANCER COMBINATION CHEMOTHERAPY; CARDIOVASCULAR RISK; CLINICAL TRIAL; HIGH RISK PATIENT; HUMAN; LETTER; LOW DRUG DOSE; MULTIPLE CYCLE TREATMENT; NEOPLASM; PRIORITY JOURNAL; TREATMENT RESPONSE; VENOUS THROMBOEMBOLISM; NOTE; RISK;

ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; HUMANS; NEOPLASMS; RISK; VENOUS THROMBOEMBOLISM;

EID: 64249135367     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2009.443     Document Type: Letter

References (5)

1. Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA. 2008;300(19):2277-2285.
2. Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349(5):427-434.
3. Kröger K, Weiland D, Ose C, et al. Risk factors for venous thromboembolic events in cancer patients. Ann Oncol. 2006;17(2):297-303.
4. Miles D, Chan A, Romieu G, et al. Randomized, double-blind, placebocontrolled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as first-line therapy for patients with locally recurrent or metastatic breast cancer (mBC) [abstract], http://www.asco.org/ASCO/ Abstracts+%26+Virtual+Meeting /Abstracts?&vmview=abst-detaiLview&conflD= 55&abstractlD=34482. Accessed January 15, 2009.
5. BEATRICE Study: a study of Avastin (bevacizumab) adjuvant therapy in triple negative breast cancer. ClinicalTrials.gov Web site, http:// clinicaltrials.gov/ct2 /show/NCT00528567. Accessed January 15, 2009.