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Volumn 5, Issue 4, 2009, Pages 1253-1264

Novel bioactive composite bone cements based on the β-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system

Author keywords

Brushite; Calcium phosphate cement; Cytotoxicity; In vitro test; Silicate

Indexed keywords

BONE; BONE CEMENT; CALCIUM PHOSPHATE; CALCIUM SILICATE; CEMENTS; COMPRESSIVE STRENGTH; SETTING; SILICATES;

EID: 64249134710     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2008.10.006     Document Type: Article
Times cited : (95)

References (53)
  • 1
    • 0029256548 scopus 로고
    • Skeletal repair by in situ formation of the mineral phase of bone
    • Constanz B.R., Ison I.C., Fulmer M., Poser R.D., and Smith S.T. Skeletal repair by in situ formation of the mineral phase of bone. Science 267 (1995) 1796-1799
    • (1995) Science , vol.267 , pp. 1796-1799
    • Constanz, B.R.1    Ison, I.C.2    Fulmer, M.3    Poser, R.D.4    Smith, S.T.5
  • 2
    • 0032972977 scopus 로고    scopus 로고
    • Intravertebral body reconstruction with an injectable in situ-setting carbonated apatite: biomechanical evaluation of a minimally invasive technique
    • Schildhauer T.A., Bennett A.P., Wright T.M., Lane J.M., and O'Leary P.F. Intravertebral body reconstruction with an injectable in situ-setting carbonated apatite: biomechanical evaluation of a minimally invasive technique. J Orthop Res 1 (1999) 67-72
    • (1999) J Orthop Res , vol.1 , pp. 67-72
    • Schildhauer, T.A.1    Bennett, A.P.2    Wright, T.M.3    Lane, J.M.4    O'Leary, P.F.5
  • 3
    • 0034255813 scopus 로고    scopus 로고
    • A novel injectable bioactive bone cement for spinal surgery: a developmental and preclinical study
    • Li Y.W., Leong J.C.Y., Lu W.W., Luk K.D.K., Cheung K.M.C., and Chiu K.Y. A novel injectable bioactive bone cement for spinal surgery: a developmental and preclinical study. J Biomed Mater Res 52 (2000) 164-170
    • (2000) J Biomed Mater Res , vol.52 , pp. 164-170
    • Li, Y.W.1    Leong, J.C.Y.2    Lu, W.W.3    Luk, K.D.K.4    Cheung, K.M.C.5    Chiu, K.Y.6
  • 4
    • 12444260707 scopus 로고    scopus 로고
    • A composition for an injectable bone mineral substitute material. PCT Int
    • Appl WO 2002005861 A1
    • Lidgren L. A composition for an injectable bone mineral substitute material. PCT Int Appl WO 2002005861 A1, 2002.
    • (2002)
    • Lidgren, L.1
  • 5
    • 0001131545 scopus 로고
    • Calcium phosphate cements for medical use: state of the art and perspectives of development
    • Letmaitre J., Mirtchi A., and Mortier A. Calcium phosphate cements for medical use: state of the art and perspectives of development. Silic Ind 10 (1987) 141-146
    • (1987) Silic Ind , vol.10 , pp. 141-146
    • Letmaitre, J.1    Mirtchi, A.2    Mortier, A.3
  • 7
    • 13444259693 scopus 로고    scopus 로고
    • Biocompatibility and resorption of a brushite calcium phosphate cement
    • Theiss F., Apelt D., Brand B., Kutter A., Zlinszky K., Bohner M., et al. Biocompatibility and resorption of a brushite calcium phosphate cement. Biomaterials 26 (2005) 4383-4394
    • (2005) Biomaterials , vol.26 , pp. 4383-4394
    • Theiss, F.1    Apelt, D.2    Brand, B.3    Kutter, A.4    Zlinszky, K.5    Bohner, M.6
  • 9
    • 0038692860 scopus 로고    scopus 로고
    • Mechanical activation and cement formation of β-tricalcium phosphate
    • Gbureck U., Grolms O., Barralet J.E., Grover L.M., and Thull R. Mechanical activation and cement formation of β-tricalcium phosphate. Biomaterials 24 (2003) 4123-4131
    • (2003) Biomaterials , vol.24 , pp. 4123-4131
    • Gbureck, U.1    Grolms, O.2    Barralet, J.E.3    Grover, L.M.4    Thull, R.5
  • 10
    • 33646857935 scopus 로고    scopus 로고
    • In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line
    • Xia Z., Grover L.M., Huang Y., Adamopoulos I.E., Gbureck U., Triffitt J.T., et al. In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line. Biomaterials 27 (2006) 4557-4565
    • (2006) Biomaterials , vol.27 , pp. 4557-4565
    • Xia, Z.1    Grover, L.M.2    Huang, Y.3    Adamopoulos, I.E.4    Gbureck, U.5    Triffitt, J.T.6
  • 11
    • 29144523850 scopus 로고    scopus 로고
    • Temperature dependent setting kinetics and mechanical properties of β-TCP-pyrophosphoric acid bone cement
    • Grover L.M., Gbureck U., Young A.M., Wright A.J., and Barralet J.E. Temperature dependent setting kinetics and mechanical properties of β-TCP-pyrophosphoric acid bone cement. J Mater Chem 15 (2005) 4955-4962
    • (2005) J Mater Chem , vol.15 , pp. 4955-4962
    • Grover, L.M.1    Gbureck, U.2    Young, A.M.3    Wright, A.J.4    Barralet, J.E.5
  • 12
    • 34249039959 scopus 로고    scopus 로고
    • Increase of the final setting time of the brushite cement by using chondroitin 4-sulfate and silica gel
    • Marino F.T., Mastio J., Rueda C., Blanco L., and Cabarcos E.L. Increase of the final setting time of the brushite cement by using chondroitin 4-sulfate and silica gel. J Mater Sci Mater Med 18 (2007) 1195-1201
    • (2007) J Mater Sci Mater Med , vol.18 , pp. 1195-1201
    • Marino, F.T.1    Mastio, J.2    Rueda, C.3    Blanco, L.4    Cabarcos, E.L.5
  • 13
    • 0037333668 scopus 로고    scopus 로고
    • Histological evaluation of the bone response to calcium phosphate cement implanted in cortical bone
    • Ooms E.M., Wolke J.G.C., Heuvel M.T., Jeschke B., and Jansen J.A. Histological evaluation of the bone response to calcium phosphate cement implanted in cortical bone. Biomaterials 24 (2003) 989-1000
    • (2003) Biomaterials , vol.24 , pp. 989-1000
    • Ooms, E.M.1    Wolke, J.G.C.2    Heuvel, M.T.3    Jeschke, B.4    Jansen, J.A.5
  • 14
    • 16244411964 scopus 로고    scopus 로고
    • The inflammatory of biphasic calcium phosphate granules in osteoblast/macrophage co-culture
    • Curran J.M., Gallagher J.A., and Hunt J.A. The inflammatory of biphasic calcium phosphate granules in osteoblast/macrophage co-culture. Biomaterials 26 (2005) 5313-5320
    • (2005) Biomaterials , vol.26 , pp. 5313-5320
    • Curran, J.M.1    Gallagher, J.A.2    Hunt, J.A.3
  • 15
    • 0000662411 scopus 로고
    • Apatite formation on bioactive ceramics in body environment
    • Oonishi, Aoki H., and Sawai K. (Eds), Ishiyaku EuroAmerica, Tokyo
    • Kokubo T., Kushiyani M., Ebisawa Y., Kitsugi, Kotani S., Oura K., et al. Apatite formation on bioactive ceramics in body environment. In: Oonishi, Aoki H., and Sawai K. (Eds). Bioceramics (1988), Ishiyaku EuroAmerica, Tokyo 157-162
    • (1988) Bioceramics , pp. 157-162
    • Kokubo, T.1    Kushiyani, M.2    Ebisawa, Y.3    Kitsugi4    Kotani, S.5    Oura, K.6
  • 16
    • 0030560768 scopus 로고    scopus 로고
    • Subchondral bone and cartilage repair with bioactive glasses, hydroxyapatite, and hydroxyapatite-glass composite
    • Suominen E., Aho A.J., Vedel E., Kangasniemi I., Uusipaikka E., and Yli-Urpo A. Subchondral bone and cartilage repair with bioactive glasses, hydroxyapatite, and hydroxyapatite-glass composite. J Biomed Mater Res 32 (1996) 543-551
    • (1996) J Biomed Mater Res , vol.32 , pp. 543-551
    • Suominen, E.1    Aho, A.J.2    Vedel, E.3    Kangasniemi, I.4    Uusipaikka, E.5    Yli-Urpo, A.6
  • 17
    • 0031555506 scopus 로고    scopus 로고
    • Bioactive bone cement: comparison of AW-GC filler with hydroxyapatite and β-TCP fillers on the mechanical and biological properties
    • Kobayashi M., Nakamura T., Tamura J., Kokubo T., and Kikutani T. Bioactive bone cement: comparison of AW-GC filler with hydroxyapatite and β-TCP fillers on the mechanical and biological properties. J Biomed Mater Res 37 (1997) 301-313
    • (1997) J Biomed Mater Res , vol.37 , pp. 301-313
    • Kobayashi, M.1    Nakamura, T.2    Tamura, J.3    Kokubo, T.4    Kikutani, T.5
  • 18
    • 0032210732 scopus 로고    scopus 로고
    • Bioactive bone cement: comparison of apatite and wollastonite containing glass-ceramic, hydrxyapatite and β-tricalcium phosphate fillers on bone-bonding strength
    • Kobayashi M., Nakamura T., Okada Y., Fukumoto A., Furukawa T., Kato H., et al. Bioactive bone cement: comparison of apatite and wollastonite containing glass-ceramic, hydrxyapatite and β-tricalcium phosphate fillers on bone-bonding strength. J Biomed Mater Res 42 (1998) 223-237
    • (1998) J Biomed Mater Res , vol.42 , pp. 223-237
    • Kobayashi, M.1    Nakamura, T.2    Okada, Y.3    Fukumoto, A.4    Furukawa, T.5    Kato, H.6
  • 19
    • 2942577983 scopus 로고    scopus 로고
    • Sol-gel synthesis and in vitro bioactivity of tricalcium silicate powders
    • Zhao W., and Chang J. Sol-gel synthesis and in vitro bioactivity of tricalcium silicate powders. Mater Lett 58 (2004) 2350-2353
    • (2004) Mater Lett , vol.58 , pp. 2350-2353
    • Zhao, W.1    Chang, J.2
  • 20
    • 20444449817 scopus 로고    scopus 로고
    • The self-setting properties and in vitro bioactivity of tricalcium silicate
    • Zhao W.Y., Wang J.Y., Zhai W.Y., Wang Z., and Chang J. The self-setting properties and in vitro bioactivity of tricalcium silicate. Biomaterials 26 (2005) 6113-6121
    • (2005) Biomaterials , vol.26 , pp. 6113-6121
    • Zhao, W.Y.1    Wang, J.Y.2    Zhai, W.Y.3    Wang, Z.4    Chang, J.5
  • 21
    • 33846156545 scopus 로고    scopus 로고
    • Chemical analysis of silica doped hydroxyapatite biomaterials consolidated by a spark plasma sintering method
    • Xu J.L., and Khor K.A. Chemical analysis of silica doped hydroxyapatite biomaterials consolidated by a spark plasma sintering method. J Inorg Biochem 101 (2007) 187-195
    • (2007) J Inorg Biochem , vol.101 , pp. 187-195
    • Xu, J.L.1    Khor, K.A.2
  • 22
    • 31044443628 scopus 로고    scopus 로고
    • The response of osteoblasts to nanocrystalline silicon-substituted hydroxyapatite thin films
    • Thian E.S., Huang J., Best S.M., Barber Z.H., Brooks R.A., Rushton N., et al. The response of osteoblasts to nanocrystalline silicon-substituted hydroxyapatite thin films. Biomaterials 27 (2006) 2692-2698
    • (2006) Biomaterials , vol.27 , pp. 2692-2698
    • Thian, E.S.1    Huang, J.2    Best, S.M.3    Barber, Z.H.4    Brooks, R.A.5    Rushton, N.6
  • 23
    • 33746886291 scopus 로고    scopus 로고
    • Nanoscale characterization of the interface between bone and hydroxyapatite implants and the effect of silicon on bone apposition
    • Porter A.E. Nanoscale characterization of the interface between bone and hydroxyapatite implants and the effect of silicon on bone apposition. Micron 37 (2006) 681-688
    • (2006) Micron , vol.37 , pp. 681-688
    • Porter, A.E.1
  • 24
    • 0035093572 scopus 로고    scopus 로고
    • Gene-expression profiling of human osteoblasts following treatment with ionic products of biological 45S5 dissolution
    • Xynos I.D., Edgar A.J., Buttery L.D., Hench L.L., and Polak J.M. Gene-expression profiling of human osteoblasts following treatment with ionic products of biological 45S5 dissolution. J Biomed Mater Res 55 (2001) 151-157
    • (2001) J Biomed Mater Res , vol.55 , pp. 151-157
    • Xynos, I.D.1    Edgar, A.J.2    Buttery, L.D.3    Hench, L.L.4    Polak, J.M.5
  • 25
    • 0024820685 scopus 로고
    • Calcium phosphate cements: study of the β-tricalcium phosphate-monocalcium phosphate system
    • Mirtchi A.A., Lemaitre J., and Terao N. Calcium phosphate cements: study of the β-tricalcium phosphate-monocalcium phosphate system. Biomaterials 10 (1989) 634-638
    • (1989) Biomaterials , vol.10 , pp. 634-638
    • Mirtchi, A.A.1    Lemaitre, J.2    Terao, N.3
  • 26
    • 7444269882 scopus 로고    scopus 로고
    • Injectablity of calcium phosphate pastes
    • Bohner M., and Baroud G. Injectablity of calcium phosphate pastes. Biomaterials 26 (2005) 1553-1563
    • (2005) Biomaterials , vol.26 , pp. 1553-1563
    • Bohner, M.1    Baroud, G.2
  • 28
    • 0038015699 scopus 로고    scopus 로고
    • In vitro ageing of brushite calcium phosphate cement
    • Grover L.M., Knowles J.C., Fleming G.J.P., and Barralet. In vitro ageing of brushite calcium phosphate cement. Biomaterials 24 (2003) 4133-4141
    • (2003) Biomaterials , vol.24 , pp. 4133-4141
    • Grover, L.M.1    Knowles, J.C.2    Fleming, G.J.P.3    Barralet4
  • 29
    • 34547135175 scopus 로고    scopus 로고
    • Novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement
    • Huan Z.G., and Chang J. Novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement. J Biomed Mater Res Part B Appl Biomater 82 B (2007) 352-359
    • (2007) J Biomed Mater Res Part B Appl Biomater , vol.82 , Issue.B , pp. 352-359
    • Huan, Z.G.1    Chang, J.2
  • 30
    • 0036828604 scopus 로고
    • PH-metric study of the setting reaction of monocalcium phosphate monohydrate/calcium oxide-based cements
    • Nurit J., Margerit J., Terol A., and Boudeville P. PH-metric study of the setting reaction of monocalcium phosphate monohydrate/calcium oxide-based cements. J Mater Sci Mater Med 13 (1993) 1007-1014
    • (1993) J Mater Sci Mater Med , vol.13 , pp. 1007-1014
    • Nurit, J.1    Margerit, J.2    Terol, A.3    Boudeville, P.4
  • 31
    • 0025418004 scopus 로고
    • Surface chemistry of bioactive glass-ceramics
    • Kokubo T. Surface chemistry of bioactive glass-ceramics. J Non-Crystallogr Solids 120 (1990) 138-151
    • (1990) J Non-Crystallogr Solids , vol.120 , pp. 138-151
    • Kokubo, T.1
  • 32
    • 32144437418 scopus 로고    scopus 로고
    • How useful is SBF in predicting in vivo bone bioactivity
    • Kokubo T., and Takadama H. How useful is SBF in predicting in vivo bone bioactivity. Biomaterials 27 (2006) 2907-2915
    • (2006) Biomaterials , vol.27 , pp. 2907-2915
    • Kokubo, T.1    Takadama, H.2
  • 33
    • 0003419125 scopus 로고    scopus 로고
    • Biological evaluation of medical devices - Part 5. Tests for cytotoxicity, in vitro methods: 8.2 tests on extract
    • ISO/EN 10993-5
    • ISO/EN 10993-5. Biological evaluation of medical devices - Part 5. Tests for cytotoxicity, in vitro methods: 8.2 tests on extract.
  • 34
    • 0025899234 scopus 로고
    • Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
    • Cory A.H., Owen T.C., Barltrop J.A., and Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 3 (1991) 207-212
    • (1991) Cancer Commun , vol.3 , pp. 207-212
    • Cory, A.H.1    Owen, T.C.2    Barltrop, J.A.3    Cory, J.G.4
  • 35
    • 9444244379 scopus 로고    scopus 로고
    • Hydrolysis and cytocompatibility of zinc-containing α-tricalcium phosphate powder
    • Sogo Y., Ito A., Kamo M., Sakurai T., Onuma K., Ichinose N., et al. Hydrolysis and cytocompatibility of zinc-containing α-tricalcium phosphate powder. Mater Sci Eng C 24 (2004) 709-715
    • (2004) Mater Sci Eng C , vol.24 , pp. 709-715
    • Sogo, Y.1    Ito, A.2    Kamo, M.3    Sakurai, T.4    Onuma, K.5    Ichinose, N.6
  • 36
    • 33847221143 scopus 로고    scopus 로고
    • Premixed calcium phosphate cements: synthesis, physical properties, and cell cytotoxicity
    • Xu H.H.K., Carey L.E., Simon C.G., Takagi S., and Chow L.C. Premixed calcium phosphate cements: synthesis, physical properties, and cell cytotoxicity. Dent Mater 23 (2007) 433-441
    • (2007) Dent Mater , vol.23 , pp. 433-441
    • Xu, H.H.K.1    Carey, L.E.2    Simon, C.G.3    Takagi, S.4    Chow, L.C.5
  • 37
    • 10644267768 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering
    • Mauney J.R., Jaquiery C., Volloch V., Heberer M., Martin I., and Kaplan D.L. In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering. Biomaterials 26 (2005) 3173-3185
    • (2005) Biomaterials , vol.26 , pp. 3173-3185
    • Mauney, J.R.1    Jaquiery, C.2    Volloch, V.3    Heberer, M.4    Martin, I.5    Kaplan, D.L.6
  • 38
  • 39
    • 22644442740 scopus 로고    scopus 로고
    • Technological issues for the development of more efficient calcium phosphate bone cement: a critical assessment
    • Bohner M., Gbureck U., and Barralet J.E. Technological issues for the development of more efficient calcium phosphate bone cement: a critical assessment. Biomaterials 26 (2005) 6423-6429
    • (2005) Biomaterials , vol.26 , pp. 6423-6429
    • Bohner, M.1    Gbureck, U.2    Barralet, J.E.3
  • 40
    • 0346499554 scopus 로고    scopus 로고
    • Ionic modification of calcium phosphate cement viscosity. Part II. Hypodermic injection and strength improvement of brushite cement
    • Barralet J.E., Grover L.M., and Gbureck U. Ionic modification of calcium phosphate cement viscosity. Part II. Hypodermic injection and strength improvement of brushite cement. Biomaterials 25 (2004) 2197-2203
    • (2004) Biomaterials , vol.25 , pp. 2197-2203
    • Barralet, J.E.1    Grover, L.M.2    Gbureck, U.3
  • 42
    • 34748892318 scopus 로고    scopus 로고
    • Reactivity of calcium phosphate cements
    • Bohner M. Reactivity of calcium phosphate cements. J Mater Chem 17 (2007) 3980-3986
    • (2007) J Mater Chem , Issue.17 , pp. 3980-3986
    • Bohner, M.1
  • 43
    • 34447257190 scopus 로고    scopus 로고
    • Silicon substitution in the calcium phosphate bioceramics
    • Pietak A.M., Reid J.W., Scott M.J., and Sayer M. Silicon substitution in the calcium phosphate bioceramics. Biomaterials 28 (2007) 4023-4032
    • (2007) Biomaterials , vol.28 , pp. 4023-4032
    • Pietak, A.M.1    Reid, J.W.2    Scott, M.J.3    Sayer, M.4
  • 44
    • 34347351989 scopus 로고    scopus 로고
    • Self-setting properties of a β-dicalcium silicate reinforced calcium phosphate cement
    • Wang X.P., Ye J.D., Wang Y.J., and Chen L. Self-setting properties of a β-dicalcium silicate reinforced calcium phosphate cement. J Biomed Mater Res Part B Appl Biomater 82 (2007) 93-99
    • (2007) J Biomed Mater Res Part B Appl Biomater , vol.82 , pp. 93-99
    • Wang, X.P.1    Ye, J.D.2    Wang, Y.J.3    Chen, L.4
  • 45
    • 34548544482 scopus 로고    scopus 로고
    • Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate-tricalcium silicate composite bone cements
    • Huan Z.G., and Chang J. Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate-tricalcium silicate composite bone cements. Acta Biomater 3 (2007) 952-960
    • (2007) Acta Biomater , vol.3 , pp. 952-960
    • Huan, Z.G.1    Chang, J.2
  • 46
    • 0033567842 scopus 로고    scopus 로고
    • Effect of bioactive filler content on mechanical properties and osteoconductivity of bioactive bone cement
    • Kobayashi M., Nakamura T., Shinzato S., Mousa W.F., Nishio K., Ohsawa K., et al. Effect of bioactive filler content on mechanical properties and osteoconductivity of bioactive bone cement. J Biomed Mater Res 46 (1999) 447-457
    • (1999) J Biomed Mater Res , vol.46 , pp. 447-457
    • Kobayashi, M.1    Nakamura, T.2    Shinzato, S.3    Mousa, W.F.4    Nishio, K.5    Ohsawa, K.6
  • 47
    • 0036677577 scopus 로고    scopus 로고
    • Setting behavior and in vitro bioactivity of hydroxyapatite/calcium sulfate cements
    • Cabaňas M.V., Rodríguez-Lorenzo L.M., and Vallet-Regí M. Setting behavior and in vitro bioactivity of hydroxyapatite/calcium sulfate cements. Chem Mater 14 (2002) 3550-3555
    • (2002) Chem Mater , vol.14 , pp. 3550-3555
    • Cabaňas, M.V.1    Rodríguez-Lorenzo, L.M.2    Vallet-Regí, M.3
  • 48
    • 0001197835 scopus 로고    scopus 로고
    • Biological applications of bioactive glasses
    • Hench L.L., and West J.K. Biological applications of bioactive glasses. Life Chem Rep 13 (1996) 187-241
    • (1996) Life Chem Rep , vol.13 , pp. 187-241
    • Hench, L.L.1    West, J.K.2
  • 49
    • 10044265238 scopus 로고    scopus 로고
    • Characterization of adhesion and differentiation markers of osteogenic marrow stromal cells
    • Marom R., Shur I., Solomon R., and Benayahu D. Characterization of adhesion and differentiation markers of osteogenic marrow stromal cells. J Cell Physiol 202 (2005) 41-48
    • (2005) J Cell Physiol , vol.202 , pp. 41-48
    • Marom, R.1    Shur, I.2    Solomon, R.3    Benayahu, D.4
  • 50
    • 0035315760 scopus 로고    scopus 로고
    • Temporal and local appearance of alkaline phosphatase activity in early stages of guided bone regeneration: a descriptive histochemical study in humans
    • Stucki U., Schmid J., Hammerle C.F., and Lang N.P. Temporal and local appearance of alkaline phosphatase activity in early stages of guided bone regeneration: a descriptive histochemical study in humans. Clin Oral Implant Res 12 (2001) 121-127
    • (2001) Clin Oral Implant Res , vol.12 , pp. 121-127
    • Stucki, U.1    Schmid, J.2    Hammerle, C.F.3    Lang, N.P.4
  • 51
    • 0037291292 scopus 로고    scopus 로고
    • Orthosilicic acid stimulates collagen type I synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro
    • Reffitt D.M., Ogston N., Jugdaohsingh R., Cheung H.F., Evans B.A., Thompson R.P., et al. Orthosilicic acid stimulates collagen type I synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone 32 (2003) 127-135
    • (2003) Bone , vol.32 , pp. 127-135
    • Reffitt, D.M.1    Ogston, N.2    Jugdaohsingh, R.3    Cheung, H.F.4    Evans, B.A.5    Thompson, R.P.6
  • 53
    • 33748038028 scopus 로고    scopus 로고
    • Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite-bioactive ceramics
    • Sun H.L., Wu C.T., Dai K.R., Chang J., and Tang T.T. Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite-bioactive ceramics. Biomaterials 27 (2006) 5651-5657
    • (2006) Biomaterials , vol.27 , pp. 5651-5657
    • Sun, H.L.1    Wu, C.T.2    Dai, K.R.3    Chang, J.4    Tang, T.T.5


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