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Volumn 29, Issue 1, 2009, Pages 35-45

Solamargine induces apoptosis and enhances susceptibility to trastuzumab and epirubicin in breast cancer cells with low or high expression levels of HER2/neu

Author keywords

Epirubicin (EPI); HER2 neu; Solamargine (SM); Topoisomerase IIa (TopoIIa); Trastuzumab

Indexed keywords

ANTINEOPLASTIC AGENT; BETA SOLAMARIN; BETA-SOLAMARINE; EPIRUBICIN; MONOCLONAL ANTIBODY; SOLANUM ALKALOID; TRASTUZUMAB;

EID: 64249110664     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20080028     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0036805488 scopus 로고    scopus 로고
    • Cell proliferation, nuclear ploidy, and egfr and her2/neu tyrosine kinase oncoproteins in infiltrating ductal breast carcinoma
    • Fernandez Val, J. F., Losada, J., Arregui Murua, M. A. and Sarria, R. (2002) Cell proliferation, nuclear ploidy, and EGFr and HER2/neu tyrosine kinase oncoproteins in infiltrating ductal breast carcinoma. Cancer Genet. Cytogenet. 138, 69-72
    • (2002) Cancer Genet. Cytogenet. , vol.138 , pp. 69-72
    • Fernandez Val, J.F.1    Losada, J.2    Arregui Murua, M.A.3    Sarria, R.4
  • 2
    • 0032472938 scopus 로고    scopus 로고
    • A strain independent postnatal neurodegeneration in mice lacking the egf receptor
    • Sibilia, M., Steinbach, J. P., Stingl, L., Aguzzi, A. and Wagner, E. F. (1998) A strain independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J. 17, 719-731
    • (1998) EMBO J. , vol.17 , pp. 719-731
    • Sibilia, M.1    Steinbach, J.P.2    Stingl, L.3    Aguzzi, A.4    Wagner, E.F.5
  • 6
    • 0030947407 scopus 로고    scopus 로고
    • Her2 overexpression and paclitaxel sensitivity in breast cancer: Therapeutic implications
    • Baselga, J., Seidman, A. D., Rosen, P. P. and Norton, L. (1997) HER2 overexpression and paclitaxel sensitivity in breast cancer: therapeutic implications. Oncology 11, 43-48
    • (1997) Oncology , vol.11 , pp. 43-48
    • Baselga, J.1    Seidman, A.D.2    Rosen, P.P.3    Norton, L.4
  • 7
    • 0025332351 scopus 로고
    • Amplification of the c-erb b-2 oncogene and prognosis of breast adenocarcinoma
    • Heintz, N. H., Leslie, K. O., Rogers, L. A. and Howard, P. L. (1990) Amplification of the c-erb B-2 oncogene and prognosis of breast adenocarcinoma. Arch. Pathol. Lab. Med. 114, 160-163
    • (1990) Arch. Pathol. Lab. Med. , Issue.114 , pp. 160-163
    • Heintz, N.H.1    Leslie, K.O.2    Rogers, L.A.3    Howard, P.L.4
  • 10
    • 0036784463 scopus 로고    scopus 로고
    • Trastuzumab-associated cardiotoxicity
    • Keefe, D. L. (2002) Trastuzumab-associated cardiotoxicity. Cancer 95, 1592-1600
    • (2002) Cancer , vol.95 , pp. 1592-1600
    • Keefe, D.L.1
  • 12
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-her2 monoclonal antibody in women who have her2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh, M. A., Vogel, C. L., Tripathy, D., Robert, N. J., Scholl, S., Fehrenbacher, L., Wolter, J. M., Paton, V., Shak, S., Lieberman, G. and Slamon, D. J. (1999) Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J. Clin. Oncol. 17, 2639-2648
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.M.7    Paton, V.8    Shak, S.9    Lieberman, G.10    Slamon, D.J.11
  • 13
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-her2 antibody (herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against her2/neu overexpressing human breast cancer xenografts
    • Baselga, J., Norton, L., Albanell, J., Kim, Y. M. and Mendelsohn, J. (1998) Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res. 58, 2825-2831
    • (1998) Cancer Res. , Issue.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.4    Mendelsohn, J.5
  • 16
    • 0033026287 scopus 로고    scopus 로고
    • Antineoplastic agents, iii: Steroidal glycosides from solanum nigrum
    • Hu, K., Kobayashi, H., Dong, A., Jing, Y., Iwasaki, S. and Yao, X. (1999) Antineoplastic agents, III: steroidal glycosides from Solanum nigrum. Planta Med. 65. 35-38
    • (1999) Planta Med. , vol.65 , pp. 35-38
    • Hu, K.1    Kobayashi, H.2    Dong, A.3    Jing, Y.4    Iwasaki, S.5    Yao, X.6
  • 17
    • 7544237949 scopus 로고    scopus 로고
    • Action of solamargine on human lung cancer cells-enhancement of the susceptibility of cancer cells to tnfs
    • Liu, L. F., Liang, C. H., Shiu, L. Y., Lin, W. L., Lin, C. C. and Kuo, K. W. (2004) Action of solamargine on human lung cancer cells-enhancement of the susceptibility of cancer cells to TNFs. FEBS Lett. 577, 67-74
    • (2004) FEBS Lett. , vol.577 , pp. 67-74
    • Liu, L.F.1    Liang, C.H.2    Shiu, L.Y.3    Lin, W.L.4    Lin, C.C.5    Kuo, K.W.6
  • 20
    • 77956127888 scopus 로고
    • The preparation of 131i-labelled human growth hormone of high specific radioactivity
    • Greenwood, F. C., Hunter, W. H. and Glover, J. S. (1963) The preparation of 131I-labelled human growth hormone of high specific radioactivity. Biochem. J. 89, 114-123
    • (1963) Biochem. J. , vol.89 , pp. 114-123
    • Greenwood, F.C.1    Hunter, W.H.2    Glover, J.S.3
  • 21
    • 0029036955 scopus 로고
    • The search for synergy: A critical review from a response surface perspective
    • Greco, W. R., Bravo, G. and Parsons, J. C. (1995) The search for synergy: a critical review from a response surface perspective. Pharmacol. Rev. 47, 331-385
    • (1995) Pharmacol. Rev. , vol.47 , pp. 331-385
    • Greco, W.R.1    Bravo, G.2    Parsons, J.C.3
  • 23
    • 0036132653 scopus 로고    scopus 로고
    • Quantitative measurement of anti-erbb-2 antibody by flow cytometry and elisa
    • Piechocki, M. P., Pilon, S. A. and Wei, W. Z. (2002) Quantitative measurement of anti-ErbB-2 antibody by flow cytometry and ELISA. J. Immunol. Methods 259, 33-42
    • (2002) J. Immunol. Methods , vol.259 , pp. 33-42
    • Piechocki, M.P.1    Pilon, S.A.2    Wei, W.Z.3
  • 25
    • 0034473776 scopus 로고    scopus 로고
    • The role of her-2 expression in predicting response to therapy in breast cancer
    • Mass, R. (2000) The role of HER-2 expression in predicting response to therapy in breast cancer. Semin. Oncol. 27, 46-52
    • (2000) Semin. Oncol. , vol.27 , pp. 46-52
    • Mass, R.1
  • 27
    • 0026092572 scopus 로고
    • Long-term survival in breast cancer related to overexpression of the c-erbb-2 oncoprotein: An immunohistochemical study using monoclonal antibody ncl-cb11
    • Dykins, R., Corbett, I. P., Henry, J. A., Wright, C., Yuan, J., Hennessy, C., Lennard, T. J., Angus, B. and Horne, C. H. (1991) Long-term survival in breast cancer related to overexpression of the c-erbB-2 oncoprotein: an immunohistochemical study using monoclonal antibody NCL-CB11. J. Pathol. 163, 105-110
    • (1991) J. Pathol. , vol.163 , pp. 105-110
    • Dykins, R.1    Corbett, I.P.2    Henry, J.A.3    Wright, C.4    Yuan, J.5    Hennessy, C.6    Lennard, T.J.7    Angus, B.8    Horne, C.H.9
  • 28
    • 0028938935 scopus 로고
    • Immunohistochemical detection of her2/neu in patients with axillary lymph node negative breast carcinoma. A study of epidemiologic risk factors, histologic features, and prognosis
    • Rosen, P. P., Lesser, M. L., Arroyo, C. D., Cranor, M., Borgen, P. and Norton, L. (1995) Immunohistochemical detection of HER2/neu in patients with axillary lymph node negative breast carcinoma. A study of epidemiologic risk factors, histologic features, and prognosis. Cancer 75, 1320-1326
    • (1995) Cancer , vol.75 , pp. 1320-1326
    • Rosen, P.P.1    Lesser, M.L.2    Arroyo, C.D.3    Cranor, M.4    Borgen, P.5    Norton, L.6
  • 29
    • 0030870295 scopus 로고    scopus 로고
    • The effect of her-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells
    • Pegram, M. D., Finn, R. S., Arzoo, K., Beryt, M., Pietras, R. J. and Slamon, D. J. (1997) The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 15, 537-547
    • (1997) Oncogene , vol.15 , pp. 537-547
    • Pegram, M.D.1    Finn, R.S.2    Arzoo, K.3    Beryt, M.4    Pietras, R.J.5    Slamon, D.J.6
  • 30
    • 0034672536 scopus 로고    scopus 로고
    • Anticancer activity evaluation of the solanum glycoalkaloid solamargine. Triggering apoptosis in human hepatoma cells
    • Kuo, K. W., Hsu, S. H., Li, Y. P., Lin, W. L., Liu, L. F., Chang, L. C., Lin, C. C., Lin, C. N. and Sheu, H. M. (2000) Anticancer activity evaluation of the solanum glycoalkaloid solamargine. Triggering apoptosis in human hepatoma cells. Biochem. Pharmacol. 60, 1865-1873
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1865-1873
    • Kuo, K.W.1    Hsu, S.H.2    Li, Y.P.3    Lin, W.L.4    Liu, L.F.5    Chang, L.C.6    Lin, C.C.7    Lin, C.N.8    Sheu, H.M.9
  • 31
    • 37749030574 scopus 로고    scopus 로고
    • Downregulation of her2/neu receptor by solamargine enhances anticancer drug-mediated cytotoxicity in breast cancer cells with high-expressing her2/neu
    • Shiu, L. Y., Liang, C. H., Huang, Y. S., Sheu, H. M. and Kuo, K. W. (2008) Downregulation of HER2/neu receptor by solamargine enhances anticancer drug-mediated cytotoxicity in breast cancer cells with high-expressing HER2/neu. Cell. Biol. Toxicol. 24, 1-10
    • (2008) Cell. Biol. Toxicol. , vol.24 , pp. 1-10
    • Shiu, L.Y.1    Liang, C.H.2    Huang, Y.S.3    Sheu, H.M.4    Kuo, K.W.5
  • 32
    • 41649101082 scopus 로고    scopus 로고
    • Solamargine enhances her2 expression and increases the susceptibility of human lung cancer h661 and h69cells to trastuzumab and epirubicin
    • Liang, C. H., Shiu, L. Y., Chang, L. C., Sheu, H. M., Tsai, E. M. and Kuo, K. W. (2008) Solamargine enhances HER2 expression and increases the susceptibility of human lung cancer H661 and H69cells to trastuzumab and epirubicin. Chem. Res. Toxicol. 21, 393-399
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 393-399
    • Liang, C.H.1    Shiu, L.Y.2    Chang, L.C.3    Sheu, H.M.4    Tsai, E.M.5    Kuo, K.W.6
  • 33
    • 34548083138 scopus 로고    scopus 로고
    • Solamargine upregulation of fas, downregulation of her2, and enhancement of cytotoxicity using epirubicin in nsclc cells
    • Liang, C. H., Shiu, L. Y., Chang, L. C., Sheu, H. M. and Kuo, K. W. (2007) Solamargine upregulation of Fas, downregulation of HER2, and enhancement of cytotoxicity using epirubicin in NSCLC cells. Mol. Nutr. Food Res. 51, 999-1005
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 999-1005
    • Liang, C.H.1    Shiu, L.Y.2    Chang, L.C.3    Sheu, H.M.4    Kuo, K.W.5
  • 34
    • 0032789613 scopus 로고    scopus 로고
    • Human mammary epithelial cells rapidly exchange empty egfr between surface and intracellular pools
    • Burke, P. M. and Wiley, H. S. (1999) Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools. J. Cell. Physiol. 180, 448-460
    • (1999) J. Cell. Physiol. , vol.180 , pp. 448-460
    • Burke, P.M.1    Wiley, H.2
  • 35
    • 0021357886 scopus 로고
    • Down regulation of epidermal growth factor receptors: Direct demonstration of receptor degradation in human fibroblasts
    • Stoscheck, C. M. and Carpenter, G. (1984) Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J. Cell Biol. 98, 1048-1053
    • (1984) J. Cell Biol. , vol.98 , pp. 1048-1053
    • Stoscheck, C.M.1    Carpenter, G.2
  • 36
    • 0021219986 scopus 로고
    • Characterization of the metabolic turnover of epidermal growth factor receptor protein in a-431 cells
    • Stoscheck, C. M. and Carpenter, G. (1984) Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells. J. Cell. Physiol. 120, 296-302
    • (1984) J. Cell. Physiol. , vol.120 , pp. 296-302
    • Stoscheck, C.M.1    Carpenter, G.2
  • 37
    • 0025908557 scopus 로고
    • The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
    • Wiley, H. S., Herbst, J. J., Walsh, B. J., Lauffenburger, D. A., Rosenfeld, M. G. and Gill, G. N. (1991) The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 266, 11083-11094
    • (1991) J. Biol. Chem. , Issue.266 , pp. 11083-11094
    • Wiley, H.1    Herbst, J.2    Walsh, B.3    Lauffenburger, D.4    Rosenfeld, M.5    Gill, G.6
  • 39
    • 0037738887 scopus 로고    scopus 로고
    • Her-2/neu and topoisomerase iiα in breast cancer
    • Jarvinen, T. A. and Liu, E. T. (2003) HER-2/neu and topoisomerase IIα in breast cancer. Breast Cancer Res. Treat. 78, 299-311
    • (2003) Breast Cancer Res. Treat. , vol.78 , pp. 299-311
    • Jarvinen, T.A.1    Liu, E.T.2
  • 40
    • 0033870292 scopus 로고    scopus 로고
    • Amplification and deletion of topoisomerase iiα gene are common in erbb-2 amplified breast cancer and alter the sensitivity to doxorubicin
    • Jarvinen, T. A., Tanner, M., Rantanen, V., Barlund, M., Borg, A . and Gŕenman, S. (2000) Amplification and deletion of topoisomerase IIα gene are common in ErbB-2 amplified breast cancer and alter the sensitivity to doxorubicin. Am. J. Pathol. 156, 839-847
    • (2000) Am. J. Pathol. , vol.156 , pp. 839-847
    • Jarvinen, T.A.1    Tanner, M.2    Rantanen, V.3    Barlund, M.4    Borg, A.5    Gŕenman, S.6
  • 41
    • 0033568541 scopus 로고    scopus 로고
    • Adenovirus-mediated human topoisomerase iiα gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells
    • Zhou, Z., Zwelling, L. A., Kawakami, Y., An, T., Kobayashi, K., Herzog, C. and Kleinerman, E. S. (1999) Adenovirus-mediated human topoisomerase IIα gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells. Cancer Res. 59, 4618-4624
    • (1999) Cancer Res. , vol.59 , pp. 4618-4624
    • Zhou, Z.1    Zwelling, L.A.2    Kawakami, Y.3    An, T.4    Kobayashi, K.5    Herzog, C.6    Kleinerman, E.S.7
  • 42
    • 0029781038 scopus 로고    scopus 로고
    • Selection of a subpopulation with fewer dna topoisomerase iiα gene copies in a doxorubicin-resistant cell line panel
    • Withoff, S., Keith, W. N., Knol, A. J., Coutts, J. C., Hoare, S. F., Mulder, N. H. and de Vries, E. G. (1996) Selection of a subpopulation with fewer DNA topoisomerase IIα gene copies in a doxorubicin-resistant cell line panel. Br. J. Cancer 74, 502-507
    • (1996) Br. J. Cancer , vol.74 , pp. 502-507
    • Withoff, S.1    Keith, W.N.2    Knol, A.J.3    Coutts, J.C.4    Hoare, S.F.5    Mulder, N.H.6    De Vries, E.G.7


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