Chapter 6 Regulation of Antibiotic Production by Bacterial Hormones

Methods in Enzymology

Volumn 458, Issue A, 2009, Pages 143-157

  Hsiao, Nai Hua ^a   Gottelt, Marco ^a   Takano, Eriko ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RECEPTOR; ANTIBIOTIC AGENT; DNA FRAGMENT; DRUG RECEPTOR; FACTOR A; GAMMA BUTYROLACTONE 1; GAMMA BUTYROLACTONE 2; GAMMA BUTYROLACTONE 3; GAMMA BUTYROLACTONE RECEPTOR; HORMONE; IM 2; KANAMYCIN; STREPTOMYCIN; UNCLASSIFIED DRUG; VIRGINIAE BUTANOLIDE A; VIRGINIAE BUTANOLIDE B; VIRGINIAE BUTANOLIDE C; VIRGINIAE BUTANOLIDE D; VIRGINIAMYCIN;

ANTIBIOTIC BIOSYNTHESIS; ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BIOASSAY; CONCENTRATION RESPONSE; CONSENSUS SEQUENCE; DNA PROBE; DRUG MANUFACTURE; DRUG MECHANISM; DRUG RECEPTOR BINDING; EXTRACTION; GENE CLUSTER; HORMONAL REGULATION; ISOTOPE LABELING; LIQUID CULTURE; NONHUMAN; OMEGA HYGROMYCIN RESISTANCE GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; RESISTANCE GENE; REVIEW; SIGNAL TRANSDUCTION; STREPTOMYCES COELICOLOR; STREPTOMYCES GRISEUS; STREPTOMYCES VIRGINIAE;

4-BUTYROLACTONE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, BACTERIAL; KANAMYCIN; RECEPTORS, GABA-A; STREPTOMYCES;

BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 64249108113     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(09)04806-X     Document Type: Review

References (24)

1. Bibb M. Regulation of secondary metabolism in streptomycetes. Curr. Opin. Microbiol. 8 (2005) 208-215
2. Folcher M., Gaillard H., Nguyen L.T., Nguyen K.T., Lacroix P., Bamas-Jacques N., Rinkel M., and Thompson C.J. Pleiotropic functions of a Streptomyces pristinaespiralis autoregulator receptor in development, antibiotic biosynthesis, and expression of a superoxide dismutase. J. Biol. Chem. 276 (2001) 44297-44306
3. Hara O., and Beppu T. Mutants blocked in streptomycin production in Streptomyces griseus-The role of A-factor. J. Antibiot. (Tokyo) 35 (1982) 349-358
4. Horinouchi S., Nishiyama M., Suzuki H., Kumada Y., and Beppu T. The cloned Streptomyces bikiniensis A-factor determinant. J. Antibiot. (Tokyo) 38 (1985) 636-641
5. Hsiao N.H., Soeding J., Linke D., Lange C., Hertweck C., Wohlleben W., and Takano E. ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesise γ-butyrolactones. Microbiology 153 (2007) 1394-1404
6. Hsiao, N. H., Nakayama, S., Merlo, M. E., Vries, M., Bunet, R., Kitani, S., Vonk, R., Nihira, T., and Takano, E. Identification of two new γ-butyrolactones and a novel detection system in Streptomyces coelicolor and its application. (Submitted).
7. Khokhlov A.S., Tovarova I.I., Borisova L.N., Pliner S.A., Shevchenko L.N., Kornitskaia E., Ivkina N.S., and Rapoport I.A. The A-factor, responsible for streptomycin biosynthesis by mutant strains of Actinomyces streptomycini. Dokl. Akad. Nauk SSSR 177 (1967) 232-235
8. Kieser T., Bibb M.J., Buttner M.J., Chater K.F., and Hopwood D.A. Practical Streptomyces Genetics (2000), John Innes Foundation, Norwich
9. Kinoshita H., Tsuji T., Ipposhi H., Nihira T., and Yamada Y. Characterization of binding sequences for butyrolactone autoregulator receptors in streptomycetes. J. Bacteriol. 181 (1999) 5075-5080
10. Kitani S., Iida A., Izumi T.A., Maeda A., Yamada Y., and Nihira T. Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5. Gene 425 (2008) 9-16
11. Nihira T., Shimizu Y., Kim H.S., and Yamada Y. Structure-activity relationships of virginiae butanolide C, an inducer of virginiamycin production in Streptomyces virginiae. J. Antibiot. (Tokyo) 41 (1988) 1828-1837
12. Ohnishi Y., Kameyama S., Onaka H., and Horinouchi S. The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: Identification of a target gene of the A-factor receptor. Mol. Microbiol. 34 (1999) 102-111
13. Okamoto S., Nakamura K., Nihira T., and Yamada Y. Virginiae butanolide binding protein from Streptomyces virginiae. Evidence that VbrA is not the virginiae butanolide binding protein and reidentification of the true binding protein. J. Biol. Chem. 270 (1995) 12319-12326
14. Onaka H., Ando N., Nihira T., Yamada Y., Beppu T., and Horinouchi S. Cloning and characterization of the A-factor receptor gene from Streptomyces griseus. J. Bacteriol. 177 (1995) 6083-6092
15. Onaka H., and Horinouchi S. DNA-binding activity of the A-factor receptor protein and its recognition DNA sequences. Mol. Microbiol. 24 (1997) 991-1000
16. Onaka H., Nakagawa T., and Horinouchi S. Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. Mol. Microbiol. 28 (1998) 743-753
17. Pawlik K., Kotowska M., Chater K.F., Kuczek K., and Takano E. A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2). Arch. Microbiol. 187 (2007) 87-99
18. Ruengjitchatchawalya M., Nihira T., and Yamada Y. Purification and characterization of the IM-2-binding protein from Streptomyces sp. strain FRI-5. J. Bacteriol. 177 (1995) 551-557
19. Sato K., Nihira T., Sakuda S., Yanagimoto M., and Yamada Y. Isolation and structure of a new butyrolactone autoregulator from Streptomyces sp. FRI-5. J. Ferment. Bioeng. 68 (1989) 170-173
20. Takano E. γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation. Curr. Opin. Microbiol. 9 (2006) 287-294
21. Takano E., Chakraburtty R., Nihira T., Yamada Y., and Bibb M.J. A complex role for the γ-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2). Mol. Microbiol. 41 (2001) 1015-1028
22. Takano E., Kinoshita H., Mersinias V., Bucca G., Hotchkiss G., Nihira T., Smith C.P., Bibb M., Wohlleben W., and Chater K. A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor. Mol. Microbiol. 56 (2005) 465-479
23. Takano E., Nihira T., Hara Y., Jones J.J., Gershater C.J., Yamada Y., and Bibb M. Purification and structural determination of SCB1, a γ-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2). J. Biol. Chem. 275 (2000) 11010-11016
24. Yamada Y. Microbial Signalling and Communication (1999), Cambridge University Press, Cambridge, UK 177-196