Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy

Pediatric Emergency Care

Volumn 24, Issue 10, 2008, Pages 691-693

  Salazar, Maria L ^a,b,c   Eiland, Lea S ^b  

^a UNIVERSITY OF ALABAMA IN HUNTSVILLE   (United States)

^b AUBURN UNIVERSITY   (United States)

^c UAB Division of Family Medicine   (United States)

Author keywords

Adolescent; Baclofen; Cerebral palsy; Implantable; Infusion pumps; Serotonin syndrome; Withdrawal symptoms

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BACLOFEN; CODEINE; CYPROHEPTADINE; DIAZEPAM; FAMOTIDINE; IBUPROFEN; LORATADINE; MACROGOL; MORPHINE; PANTOPRAZOLE; PARACETAMOL;

ABDOMINAL PAIN; ADOLESCENT; AGITATION; ARTICLE; BLOOD CELL COUNT; BRAIN VENTRICLE PERITONEUM SHUNT; CASE REPORT; CEREBRAL PALSY; CHRONIC GASTRITIS; CLONUS; COMPUTER ASSISTED TOMOGRAPHY; DIAPHORESIS; DISEASE EXACERBATION; DRUG WITHDRAWAL; ERYTHROCYTE SEDIMENTATION RATE; ESOPHAGITIS; ESOPHAGOGASTRODUODENOSCOPY; HEMATEMESIS; HUMAN; HYDROCEPHALUS; HYPERREFLEXIA; HYPERTENSION; INFUSION PUMP; KERNICTERUS; MALE; MELENA; MUSCLE RIGIDITY; MUSCLE SPASM; NERVOUSNESS; POSTOPERATIVE PAIN; PREMATURITY; RESERVOIR; RESIDUAL VOLUME; RHABDOMYOLYSIS; RIGIDITY; SCOLIOSIS; SEROTONIN SYNDROME; SPASTICITY; SPINE FUSION; TACHYCARDIA; UPPER GASTROINTESTINAL BLEEDING; WITHDRAWAL SYNDROME; AUTONOMIC DYSREFLEXIA; CHEMICALLY INDUCED DISORDER; DIFFERENTIAL DIAGNOSIS; EQUIPMENT; INTRASPINAL DRUG ADMINISTRATION; NEUROLEPTIC MALIGNANT SYNDROME; RESTLESSNESS; SUBARACHNOID SPACE;

ABDOMINAL PAIN; ADOLESCENT; AUTONOMIC DYSREFLEXIA; BACLOFEN; CEREBRAL PALSY; DIAGNOSIS, DIFFERENTIAL; EQUIPMENT FAILURE; HUMANS; HYPERTENSION; INFUSION PUMPS, IMPLANTABLE; INJECTIONS, SPINAL; MALE; NEUROLEPTIC MALIGNANT SYNDROME; PSYCHOMOTOR AGITATION; RHABDOMYOLYSIS; SEROTONIN SYNDROME; SUBARACHNOID SPACE; SUBSTANCE WITHDRAWAL SYNDROME; TACHYCARDIA;

EID: 64249084197     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e318188a952     Document Type: Article

References (13)

1. Mohammed I, Hussain A. Intrathecal baclofen withdrawal syndrome-a life-threatening complication of baclofen pump: a case report. BMC Clin Pharmacol. 2004;4:1-5.
2. Gooch JL, Oberg WA, Grams B, et al. Complications of intrathecal baclofen pumps in children. Pediatr Neurosurg. 2003;39:1-6.
3. Rigole G, Terrini G, Cordioli Z. Intrathecal baclofen withdrawal syndrome caused by low residual volume in the pump reservoir: a report of 2 cases. Arch Phys Med Rehabil. 2004;85:2064-2066.
4. Darbari FP, Melvin JJ, Piatt JH Jr, et al. Intrathecal baclofen overdose followed by withdrawal: clinical and EEG features. Pediatr Neurol. 2005;33:373-377.
5. Alden TD, Lytle RA, Park TS, et al. Intrathecal baclofen withdrawal: a case report and review of literature. Childs Nerv Syst. 2002;18:522-525.
6. Samson-Fang L, Gooch J, Norlin C. Intrathecal baclofen withdrawal simulating neuroleptic malignant syndrome in a child with cerebral palsy. Dev Med Child Neurol. 2000;42:561-565.
7. Shirley KW, Kothare S, Piatt SH, et al. Intrathecal baclofen overdose and withdrawal. Pediatr Emerg Care. 2006;20:758-764.
8. Kao LW, Amin Y, Kirk MA, et al. Intrathecal baclofen withdrawal mimicking sepsis. J Emerg Med. 2003;24:423-427.
9. Zuckerbraun NS, Ferson SS, Albright AL, et al. Intrathecal baclofen withdrawal: emergent recognition and management. Pediatr Emerg Care. 2004;20:759-764.
10. Coffey RJ, Edgar TS, Francisco GE, et al. Abrupt withdrawal from intrathecal baclofen: recognition and management of potentially lifethreatening syndrome. Arch Phys Med Rehabil. 2002;83:735-741.
11. Ganetsky M, Brush E. Serotonin syndrome-what have we learned? Clin Pediatr Emerg Med. 2005;6:103-108.
12. Bhanushali MJ, Tuite PJ. The evaluation and management of patients with neuromuscular malignant syndrome. Neurol Clin. 2004;22:389-411.
13. Meythaler JM, Roper JF, Brunner RC. Cyproheptadine for intrathecal baclofen withdrawal. Arch Phys Med Rehabil. 2003;84:638-642.