Over-expression of c-maf by chondrocytes in osteoarthritis

Journal of International Medical Research

Volumn 37, Issue 1, 2009, Pages 129-135

  Li, T ^a   Xiao, J ^a   Wu, Z ^a   Qui, Guixing ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

C maf; Cartilage; Chondrocyte; Collagentype II; Matrix metalloproteinase 13; Osteoarthritis; Phenotype

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR C MAF; MAF PROTEIN, HUMAN;

ADULT; AGED; AMPUTATION; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTROPHY; IN SITU HYBRIDIZATION; INJURY; KNEE OSTEOARTHRITIS; PATHOGENESIS; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; TOTAL KNEE REPLACEMENT; UPREGULATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; OSTEOARTHRITIS; PATHOLOGY;

ADULT; AGED; CHONDROCYTES; GENE EXPRESSION REGULATION; HUMANS; MIDDLE AGED; OSTEOARTHRITIS; PROTO-ONCOGENE PROTEINS C-MAF; RNA, MESSENGER;

EID: 64149120741     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000903700115     Document Type: Article

References (24)

1. Martel-Pelletier J: Pathophysiology of osteoarthritis. Osteoarthritis Cartilage 2004; 12(suppl A): S31-S33.
2. Pullig O, Weseloh G, Ronneberger D, et al: Chondrocyte differentiation in human osteoarthritis: expression of osteocalcin in normal and osteoarthritic cartilage and bone. Calcif Tissue Int 2000; 67: 230-240.
3. Drissi H, Zuscik M, Rosier R, et al: Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis. Mol Aspects Med 2005; 26: 169-179.
4. 2 production. Am J Pathol 2006; 168: 131-140.
5. Kataoka K, Nishizawa M, Kawai S: Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family. J Virol 1993; 67: 2133-2141.
6. Nishizawa M, Kataoka K, Goto N, et al: v-maf, a viral oncogene that encodes a 'leucine zipper' motif. Proc Natl Acad Sci USA 1989; 86: 7711-7715.
7. Chesi M, Bergsagel PL, Shonukan OO, et al: Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood 1998; 91: 4457-4463.
8. Giudicelli F, Gilardi-Hebenstreit P, Mechta-Grigoriou F, et al: Novel activities of Mafb underlie Its dual role in hindbrain segmentation and regional specification. Dev Biol 2003; 253: 150-162.
9. Francastel C, Poindessous-Jazat V, Augery-Bourget Y, et al: NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity. Leukemia 1997; 11: 273-280.
10. + T cells in NOD mice is related to a defect of c-Maf binding to the IL-4 promoter. Eur J Immunol 2005; 35: 1408-1417.
11. Ogino H, Yasuda K: Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf. Science 1998; 280: 115-118.
12. MacLean HE, Kim JI, Glimcher MJ, et al: Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol 2003; 262: 51-63.
13. Thomas CM, Fuller CJ, Whittles CE, et al: Chondrocyte death by apoptosis is associated with cartilage matrix degradation. Osteoarthritis Cartilage 2007; 15: 27-34.
14. Kirsch T, Swoboda B, Nah H: Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage. Osteoarthritis Cartilage 2000; 8: 294-302.
15. von der Mark K, Kirsch T, Nerlich A, et al: Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy. Arthritis Rheum 1992; 35: 806-811.
16. D'Angelo M, Yan Z, Nooreyazdan M, et al: MMP-13 is induced during chondrocyte hypertrophy. J Cell Biochem 2000; 77: 678-693.
17. Aigner T, Stöss H, Weseloh G, et al: Activation of collagen type II expression in osteoarthritic and rheumatoid cartilage. Virchows Arch B Cell Pathol Incl Mol Pathol 1992; 62: 337-345.
18. Hambach L, Neureiter D, Zeiler G, et al: Severe disturbance of the distribution and expression of type VI collagen chains in osteoarthritic articular cartilage. Arthritis Rheum 1998; 41: 986-996.
19. Billinghurst RC, Dahlberg L, Ionescu M, et al: Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997; 99: 1534-1545.
20. Lefebvre V, Huang W, Harley VR, et al: SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro α1(II) collagen gene. Mol Cell Biol 1997; 17: 2336-2346.
21. Huang W, Lu N, Eberspaecher H, et al: A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene. J Biol Chem 2002; 277: 50668-50675.
22. Yatsugi N, Tsukazaki T, Osaki M, et al: Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc. J Orthop Sci 2000; 5: 150-156.
23. Peng S, Lalani S, Leavenworth JW, et al: c-Maf interacts with c-Myb to down-requlate Bcl-2 expression and increase apoptosis in peripheral CD4 cells. Eur J Immunol 2007; 37: 2868-2880.
24. Dhakshinamoorthy S, Jaiswal, AK: c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction. Oncogene 2002; 21: 5301-5312.