Apical regional wall motion abnormalities reminiscent to Tako-Tsubo cardiomyopathy following consumption of psychoactive fungi

International Journal of Cardiology

Volumn 134, Issue 1, 2009, Pages

  Nef, Holger M ^a   Möllmann, Helge ^a   Hilpert, Pirmin ^a   Krause, Nicola ^a   Troidl, Christian ^b   Weber, Michael ^a   Rolf, Andreas ^a   Dill, Thorsten ^a   Hamm, Christian ^a   Elsasser A ^a  

^a KERCKHOFF HEART CENTER   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Contractile dysfunction; Psilocybin; Psychoactive fungi; Tako Tsubo cardiomyopathy

Indexed keywords

ADRENERGIC RECEPTOR; DOPAMINE RECEPTOR; PSILOCYBINE; PSYCHOTROPIC AGENT; SEROTONIN RECEPTOR;

ACUTE CORONARY SYNDROME; ADOLESCENT; ARTICLE; CARDIOMYOPATHY; CASE REPORT; CORONARY ARTERY DISEASE; FUNGUS; HEART INFARCTION; HEART VENTRICLE FUNCTION; HEART VENTRICLE WALL MOTION; HEART VENTRICULOGRAPHY; HUMAN; HYPOKINESIA; INFLAMMATION; MALE; MUSHROOM; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; ST SEGMENT ELEVATION; TAKOTSUBO CARDIOMYOPATHY;

ACUTE CORONARY SYNDROME; ADOLESCENT; CORONARY ANGIOGRAPHY; HALLUCINOGENS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PSILOCYBINE; TAKOTSUBO CARDIOMYOPATHY;

EID: 64149118606     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.12.064     Document Type: Article

References (11)

1. Ghuran A., and Nolan J. The cardiac complications of recreational drug use. West J Med 173 6 (2000) 412-415
2. Borowiak K.S., Ciechanowski K., and Waloszczyk P. Psilocybin mushroom (Psilocybe semilanceata) intoxication with myocardial infarction. J Toxicol Clin Toxicol 36 1-2 (1998) 47-49
3. Horita A., and Weber L.J. Dephosphorylation of psilocybin to psilocin by alkaline phosphatase. Proc Soc Exp Biol Med 106 (1961) 32-34
4. Vollenweider F.X., Vollenweider-Scherpenhuyzen M.F., Babler A., Vogel H., and Hell D. Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action. NeuroReport 9 17 (1998) 3897-3902
5. Kaumann A.J., and Levy F.O. 5-Hydroxytryptamine receptors in the human cardiovascular system. Pharmacol Ther 111 3 (2006) 674-706
6. Shimizu Y., Minatoguchi S., Hashimoto K., et al. The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts. J Am Coll Cardiol 40 7 (2002) 1347-1355
7. Ghuran A., and Nolan J. Recreational drug misuse: issues for the cardiologist. Heart 83 6 (2000) 627-633
8. Cano-Martinez A., Vargas-Gonzalez A., Guarner-Lans V., and Prado-Zayago E. Isoproterenol-produced damage in amphibian heart could be mediated by adrenergic receptors located in the heart muscle. Proc West Pharmacol Soc 47 (2004) 63-66
9. Nef H.M., Mollmann H., Hilpert P., et al. Sympathoadrenergic overstimulation in Tako-Tsubo cardiomyopathy triggered by physical and emotional stress. Int J Cardiol 130 (2008) 266-268
10. Wittstein I.S., Thiemann D.R., Lima J.A., et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352 6 (2005) 539-548
11. Nef H.M., Mollmann H., Kostin S., et al. Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery. Eur Heart J 28 20 (2007) 2456-2464 [Electronic publication ahead of print, 2007 Mar 29]