Anticipation of scale up issues in pharmaceutical development

Computers and Chemical Engineering

Volumn 33, Issue 5, 2009, Pages 1051-1055

  Muller, F L ^a   Latimer, J M ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Batch process; Process development; Risk assessment; Robustness and reliability; Scale up

Indexed keywords

BATCH PROCESS; NEW PROCESS; PROCESS DEVELOPMENT; PROCESS KNOWLEDGE; PROCESS UNDERSTANDING; RISK EVALUATIONS; ROBUSTNESS AND RELIABILITY; SCALE UP; SCALING-UP;

BATCH DATA PROCESSING; RISK MANAGEMENT; RISK PERCEPTION;

RISK ASSESSMENT;

EID: 64149096404     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2008.09.015     Document Type: Article

References (6)

1. Basau P.K., Mack R.A., and Vinson J.M. Chemical Engineering in Progress 95 (1999) 82
2. Bisio A., and Kabel R.L. Scaleup of chemical processes (1985), John Wiley & Sons, New York
3. Carey J.S., Laffan D., Thomson C., and Williams M.T. Organic Biomolecular Chemistry 4 (2006) 2337
4. Double J.M., Gourlay B., and Atherton J.H. Survey of process intensification equipment requirements. Proceedings of the 7th World congress of chemical engineering O156-003 (2005) IChemE, ISBN: 0 85295 494 8
5. Hulshof L.A. The Red Queen's race in fine chemical scale up. Proceedings of the 3rd international conference on organic process research and development, July 10-12, 2000. Montreal, Canada (2000)
6. Sherlock J.P., and Brewis S N. AIChE process development, symposium, June 11-14, 2006. Palm Spring, CA, USA (2006)