Low strength of correlation between the level of serum IgA antibodies to epidermal transglutaminase and the intensity of neutrophil elastase expression in lesional skin in dermatitis herpetiformis

Dermatologia Kliniczna

Volumn 10, Issue 3, 2008, Pages 135-137

  Bowszyc Dmochowska, Monika ^a   Seraszek, Agnieszka ^a   Kaczmarek, Elzbieta ^a   Gornowicz, Justyna ^a   Dmochowski, Marian ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Computer assisted image analyses; Dermatitis herpetiformis; Epidermal transglutaminase; Neutrophil elastase

Indexed keywords

IMMUNOGLOBULIN A; LEUKOCYTE ELASTASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY;

ANTIBODY BLOOD LEVEL; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CORRELATION ANALYSIS; DERMATITIS HERPETIFORMIS; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDERMIS; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN DEPOSITION; PROTEIN EXPRESSION; SKIN BIOPSY;

EID: 64049119668     PISSN: 17307201     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Sárdy M., Kárpáti S., Merkl B., Paulsson M., Smith N.: Epidermal transglutaminase (TGase 3) is the autoantigen of dermatitis herpetiformis. J. Exp. Med., 2002, 195, 747-757.
2. Leighty L., Li N., Diaz L.A., Liu Z.: Experimental models for the autoimmune and in-flammatory blistering disease, bullous pemphigoid. Arch. Dermatol. Res., 2007, 299, 417-422.
3. Oikarinen A.I., Zone J.J., Ahmed A.R., Kiistala U., Uitto J.: Demonstration of collagenase and elastase activities in the blister fluids from bullous skin diseases. Comparison between dermatitis herpetiformis and bullous pemphigoid. J. Invest. Dermatol., 1983, 81, 261-266.
4. Oikarinen A.I., Reunala T., Zone J.J., Kiistala U., Uitto J.: Proteolytic enzymes in blister fluids from patients with dermatitis herpetiformis. Br. J. Dermatol., 1986, 114, 295-302.
5. Wolnik-Trzeciak G., Bowszyc-Dmochowska M., Dańczak-Pazdrowska A., Dmochowski M.: Przeciwciała IgA przeciwko naskórkowej i tkankowej transglutaminazie oraz śródmiȩsnej a typy skórnych złogów IgA w opryszczkowatym zapaleniu skóry. [IgA antibodies to epidermal transglutaminase, tissue transglutaminase and endomysium in relation to patterns of IgA cutaneous deposits in dermatitis herpetiformis.] Dermatol. Klin., 2005, 7, 61-65.
6. Dmochowski M., Wolnik-Trzeciak G., Bowszyc-Dmochowska M., Kaczmarek E.: On significance of autoimmunity to epidermal transglutaminase in human dermatitis herpetiformis. J. Invest. Dermatol., 2006, 126 (Suppl), 5.
7. Kaczmarek E., Strzelczyk R.: From two to three-dimentional visualisation of structures in light and confocal microscopy-application for biomedical studies. [in:] Current Issues on Multidisciplinary Microscopy Research and Education. eds. A. Mendez Vilas, L. Labajos-Broncano, Formatex, Badajoz, 2005, 289-295.
8. Bowszyc-Dmochowska M., Seraszek A., Kaczmarek E., Dmochowski M.: Ekspresja elastazy neutrofilów w chorobowo zmienionej skórze nie różni siȩ u chorych na opryszczkowate zapalenie skóry i pemfigoid pȩcherzowy. [Expression of neutrophil elastase in lesional skin is not different in patients with dermatitis herpetiformis and bullous pemphigoid.] Dermatol. Klin., 2008, 10, 59-61.
9. Munro B.H.: Correlation. [in:] Statistical Methods for Health Care Research. ed. B.H. Munro. Lippincott Williams & Wilkins, Philadelphia, 2004, 239-258.
10. Hull C.M., Liddle M., Hansen N., Meyer L.J., Schmidt L., Taylor T., Jaskowski T.D., Hill H.R., Zone J.J.: Elevation of IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis. Br. J. Dermatol., 2008, 159, 120-124.
11. Shimanovich I., Mihai S., Oostingh G.J., Ilenchuk T.T., Bröcker E.B, Opdenakker G., Zillikens D., Sitaru C.: Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid. J. Pathol., 2004, 204, 519-527.
12. Zocci L., Terrinoni A., Candi E., Ahvazi B., Bagetta G., Corasaniti M.T., Lena A.M., Melino G.: Identification of transglutaminase 3 splicing isoforms. J. Invest. Dermatol., 2007, 127, 1791-1794.
13. Salmela M.T., Pender S.L.F., Reunala T., MacDonald T., Saarialho-Kere U.: Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis. Gut, 2001, 48, 496-502.
14. Puellmann K., Kaminski W.E., Vogel M., Nebe C.T., Schroeder J., Wolf H., Beham A.W.: A variable immunoreceptor in a subpopulation of human neutrophils. Proc. Natl. Acad. Sci. USA, 2006, 103, 14441-14446.