Targeting activated microglia in Alzheimer's pathology by intraventricular delivery of a phagocytosable MRI contrast agent in APP23 transgenic mice

NeuroImage

Volumn 46, Issue 2, 2009, Pages 367-372

  Mundt, Adrian P ^a   Winter, Christine ^a   Mueller, Susanne ^a   Wuerfel, Jens ^b   Tysiak, Eva ^b   Schnorr, Jörg ^a   Taupitz, Matthias ^a   Heinz, Andreas ^a   Juckel, Georg ^a,c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Alzheimer's disease; Contrast agent; Intraventricular; MRI; Superparamagnetic iron oxide particles

Indexed keywords

CONTRAST MEDIUM; IRON OXIDE; UNCLASSIFIED DRUG; VSOP C184;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG DISTRIBUTION; HISTOPATHOLOGY; IMMUNOCOMPETENT CELL; MICROGLIA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; STEREOTAXIC SURGERY; TRANSGENIC MOUSE; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL VENTRICLES; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; FERRIC COMPOUNDS; INJECTIONS, INTRAVENTRICULAR; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; PHAGOCYTOSIS;

EID: 64049117731     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2009.01.067     Document Type: Article

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