Increased Startle Responses in Interstitial Cystitis: Evidence for Central Hyperresponsiveness to Visceral Related Threat

Journal of Urology

Volumn 181, Issue 5, 2009, Pages 2127-2133

  Twiss, Christian ^b   Kilpatrick, Lisa ^a,b   Craske, Michelle ^a,d   Buffington, C A Tony ^a,f   Ornitz, Edward ^a,b   Rodríguez, Larissa V ^b   Mayer, Emeran A ^a,b,c   Naliboff, Bruce D ^a,b,e  

^a Center for Neurobiology of Stress   (United States)

^b Department of Medicine ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^f OHIO STATE UNIVERSITY   (United States)

Author keywords

cystitis; interstitial; reflex; sensory gating; startle reaction

Indexed keywords

ABDOMINAL PAIN; ADULT; AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; AUDITORY RESPONSE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEPRESSION; ELECTRODE; ELECTROPHYSIOLOGY; EYELID REFLEX; FEMALE; HUMAN; INTERSTITIAL CYSTITIS; MUSCLE EXCITATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; STARTLE REFLEX; STATISTICAL SIGNIFICANCE;

ACOUSTIC STIMULATION; ADULT; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; CYSTITIS, INTERSTITIAL; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; MIDDLE AGED; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; PROBABILITY; REFERENCE VALUES; REFLEX, ABDOMINAL; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STARTLE REACTION; VISCERA;

EID: 64049112774     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2009.01.025     Document Type: Article

References (27)

1. Koziol J.A., Clark D.C., Gittes R.F., and Tan E.M. The natural history of interstitial cystitis: a survey of 374 patients. J Urol 149 (1993) 465
2. Stanford E.J., Dell J.R., and Parsons C.L. The emerging presence of interstitial cystitis in gynecologic patients with chronic pelvic pain. Urology 69 (2007) 53
3. Ness T.J., Powell-Boone T., Cannon R., Lloyd L.K., and Fillingim R.B. Psychophysical evidence of hypersensitivity in subjects with interstitial cystitis. J Urol 173 (2005) 1983
4. Clauw D.J. The pathogenesis of chronic pain and fatigue syndromes, with special reference to fibromyalgia. Med Hypotheses 44 (1995) 369
5. Clemens J.Q. Male and female pelvic pain disorders-is it all in their heads?. J Urol 179 (2008) 813
6. Mayer E.A., Naliboff B.D., and Chang L. Evolving pathophysiological model of functional gastrointestinal disorders: implications for treatment. Eur J Surg 587 suppl. (2002) 3
7. Mayer E.A., Naliboff B.D., and Craig A.D. Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology 131 (2006) 1925
8. Azpiroz F., Bouin M., Camilleri M., Mayer E.A., Poitras P., Serra J., et al. Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol Motil 19 (2007) 62
9. Davis M., Falls W.A., Campeau S., and Kim M. Fear-potentiated startle: a neural and pharmacological analysis. Behav Brain Res 58 (1993) 175
10. Grillon C. Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology. Biol Psychiatry 52 (2002) 958
11. Naliboff B.D., Waters A.M., Labus J.S., Kilpatrick L., Craske M.G., Chang L., et al. Increased acoustic startle responses in IBS patients during abdominal and nonabdominal threat. Psychosom Med 70 (2008) 920
12. Abrams P., Cardozo L., Fall M., Griffiths D., Rosier P., Ulmsten U., et al. The standardisation of terminology in lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Urology 61 (2003) 37
13. Zigmond A.S., and Snaith R.P. The hospital anxiety and depression scale. Acta Psychiatr Scand 67 (1983) 361
14. O'Leary M.P., Sant G.R., Fowler Jr. F.J., Whitmore K.E., and Spolarich-Kroll J. The interstitial cystitis symptom index and problem index. Urology 49 (1997) 58
15. Gracely R.H., McGrath F., and Dubner R. Ratio scales of sensory and affective verbal pain descriptors. Pain 5 (1978) 5
16. Waters A.M., Neumann D.L., Henry J., Craske M.G., and Ornitz E.M. Baseline and affective startle modulation by angry and neutral faces in 4-8-year-old anxious and non-anxious children. Biol Psychol 78 (2008) 10
17. Ornitz E.M., Guthrie D., Lane S.J., and Sugiyama T. Maturation of startle facilitation by sustained prestimulation. Psychophysiology 27 (1990) 298
18. Clemens J.Q., Brown S.O., Kozloff L., and Calhoun E.A. Predictors of symptom severity in patients with chronic prostatitis and interstitial cystitis. J Urol 175 (2006) 963
19. Böcker K.B., Baas J.M., Kenemans J.L., and Verbaten M.N. Stimulus-preceding negativity induced by fear: a manifestation of affective anticipation. Int J Psychophysiol 43 (2001) 77
20. Liang K.C., Melia K.R., Campeau S., Falls W.A., Miserendino M.J., and Davis M. Lesions of the central nucleus of the amygdala, but not the paraventricular nucleus of the hypothalamus, block the excitatory effects of corticotropin-releasing factor on the acoustic startle reflex. J Neurosci 12 (1992) 2313
21. Davis M. Are different parts of the extended amygdala involved in fear versus anxiety?. Biol Psychiatry 44 (1998) 1239
22. Alvarez R.P., Biggs A., Chen G., Pine D.S., and Grillon C. Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions. J Neurosci 28 (2008) 6211
23. Berman SM, Naliboff BD, Suyenobu B, Stains J, Gordon W, Bueller JA et al: Activations and deactivations of the human amygdala associated with visceral pain: an fMRI study. Unpublished data.
24. Talati A., Ponniah K., Strug L.J., Hodge S.E., Fyer A.J., and Weissman M.M. Panic disorder, social anxiety disorder, and a possible medical syndrome previously linked to chromosome 13. Biol Psychiatry 63 (2008) 594
25. Starcevic V., and Berle D. Cognitive specificity of anxiety disorders: a review of selected key constructs. Depress Anxiety 23 (2006) 51
26. Labus J.S., Mayer E.A., Chang L., Bolus R., and Naliboff B.D. The central role of gastrointestinal-specific anxiety in irritable bowel syndrome: further validation of the visceral sensitivity index. Psychosom Med 69 (2007) 89
27. Hanno P.M., Landis J.R., Matthews-Cook Y., Kusek J., and Nyberg Jr. L. The diagnosis of interstitial cystitis revisited: lessons learned from the National Institutes of Health Interstitial Cystitis Database study. J Urol 161 (1999) 553