Soluble protein C receptor: Why?

Blood

Volumn 111, Issue 7, 2008, Pages 3301-3302

  Geiger, Margarethe ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; ENDOTHELIAL PROTEIN C RECEPTOR; MESSENGER RNA; PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1;

ALTERNATIVE RNA SPLICING; BLOOD CLOTTING; CELL PROTECTION; CELL SURFACE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; GENETIC POLYMORPHISM; HAPLOTYPE; HUMAN; NOTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RECEPTOR AFFINITY; RECEPTOR DENSITY; RISK FACTOR; SEQUENCE HOMOLOGY; THROMBOSIS;

EID: 64049112612     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-01-131482     Document Type: Note

References (5)

1. Mosnier LO, Zlokovic BV, Griffin JH. The cytoprotective protein C pathway. Blood. 2007;109: 3161-3172.
2. Esmon CT. The endothelial protein C receptor. Curr Opin Hematol. 2006;13:382-385.
3. Saposnik B, Reny JL, Gaussem P, et al. A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis. Blood. 2004;103:1311-1318.
4. Qu D, Wang Y, Song Y, Esmon NL, Esmon CT. The Ser219-> Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype. J Thromb Haemost. 2006;4:229-235.
5. Beaulieu LM, Church FC. Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. Exp Cell Res. 2007;313:677-687.