Predicting visual sensitivity in retinal prosthesis patients

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 4, 2009, Pages 1483-1491

  Horsager, Alan ^a,b   Greenwald, Scott H ^c   Weiland, James D ^a   Humayun, Mark S ^a   Greenberg, Robert J ^c   McMahon, Matthew J ^c   Boynton, Geoffrey M ^d   Fine, Ione ^d  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Second Sight Medical Products Inc   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRIGHTNESS; CASE REPORT; CLINICAL TRIAL; ELECTRODE; EPIRETINAL MEMBRANE; FUNCTIONAL ELECTRICAL STIMULATION; HUMAN; PREDICTION; PRIORITY JOURNAL; PSYCHOMETRY; VISION; VISUAL PROSTHESIS; VISUAL SYSTEM; VISUAL THRESHOLD; BIOLOGICAL MODEL; BLINDNESS; ELECTROSTIMULATION; IMPLANTATION; MICROELECTRODE; MIDDLE AGED; PATHOPHYSIOLOGY; PERCEPTIVE THRESHOLD; PHOTOSTIMULATION; PHYSIOLOGY; RETINA; RETINA DEGENERATION;

BLINDNESS; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; HUMANS; MICROELECTRODES; MIDDLE AGED; MODELS, BIOLOGICAL; PHOTIC STIMULATION; PROSTHESIS IMPLANTATION; RETINA; RETINAL DEGENERATION; SENSORY THRESHOLDS; VISUAL PERCEPTION;

EID: 64049104994     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2595     Document Type: Article

References (62)

1. Bunker CH, Berson EL, Bromley WC, Hayes RP, Roderick TH. Prevalence of retinitis pigmentosa in Maine. Am J Ophthalmol. 1984;97:357-365.
2. Heckenlively JR, Foxman SG, Parelhoff ES. Retinal dystrophy and macular coloboma. Doc Ophthalmol. 1988;68:257-271.
3. Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States.[see comment]. Arch Ophthalmol. 2004;122:564-572.
4. Santos A, Humayun MS, de Juan E Jr, et al. Preservation of the inner retina in retinitis pigmentosa: a morphometric analysis. Arch Ophthalmol. 1997;115:511-515.
5. Humayun MS, Prince M, de Juan E Jr, et al. Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1999;40:143-148.
6. Jones BW, Watt CB, Marc RE. Retinal remodelling. Clin Exp Optometry. 2005;88:282-291.
7. Marc RE, Jones BW. Retinal remodeling in inherited photoreceptor degenerations. Mol Neurobiol. 2003;28:139-147.
8. Daiger SP, Bowne SJ, Sullivan LS. Perspective on genes and mutations causing retinitis pigmentosa. Arch Ophthalmol. 2007;125: 151-158.
9. Banghart M, Borges K, Isacoff E, Trauner D, Kramer RH. Light-activated ion channels for remote control of neuronal firing. Nat Neurosci. 2004;7:1381-1386.
10. Chambers JJ, Banghart MR, Trauner D, Kramer RH. Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. J Neurophysiol. 2006;96:2792-2796.
11. Szobota S, Gorostiza P, Del Bene F, et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron. 2007;54:535-545.
12. Nagel G, Szellas T, Huhn W, et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci USA.2003;100:13940-13945.
13. Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci. 2005;8:1263-1268.
14. Bi A, Cui J, Ma YP, et al. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron. 2006;50:23-33.
15. Lagali PS, Balya D, Awatramani GB, et al. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nat Neurosci. 2008;11(6):667-675.
16. Petreanu L, Huber D, Sobczyk A, Svoboda K. Channel rhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat Neurosci. 2007;10:663-668.
17. Zhang F, Wang LP, Brauner M, et al. Multimodal fast optical interrogation of neural circuitry. Nature. 2007;446:633-639.
18. Humayun MS, de Juan E Jr, Weiland JD, et al. Pattern electrical stimulation of the human retina. Vision Res. 1999;39:2569-2576.
19. Rizzo JF III, Wyatt J, Loewenstein J, Kelly S, Shire D. Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials. Invest Ophthalmol Vis Sci. 2003;44:5362-5369.
20. Weiland JD, Yanai D, Mahadevappa M, et al. Visual task performance in blind humans with retinal prosthetic implants. Proceedings of the 26th Annual International Conference of the IEEE EMBS, San Francisco, CA, 2004. New York: IEEE Publishing Services; 2004;2:4172-4173.
21. Yanai D, Weiland JD, Mahadevappa M, Greenberg RJ, Fine I, Humayun MS. Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosa. Am J Ophthalmol. 2007; 143:820-827.
22. Humayun MS, Weiland JD, Fujii GY, et al. Visual perception in a blind subject with a chronic microelectronic retinal prosthesis. Vision Res. 2003;43:2573-2581.
23. Mahadevappa M, Weiland JD, Yanai D, Fine I, Greenberg RJ, Humayun MS. Perceptual thresholds and electrode impedance in three retinal prosthesis subjects. IEEE Trans Neural Syst Rehabil Eng. 2005;13:201-206.
24. Jensen RJ, Rizzo JF III, Ziv OR, Grumet A, Wyatt J. Thresholds for activation of rabbit retinal ganglion cells with an ultrafine, extracellular microelectrode. Invest Ophthalmol Vis Sci. 2003;44:3533-3543.
25. Jensen RJ, Ziv OR, Rizzo JF III. Thresholds for activation of rabbit retinal ganglion cells with relatively large, extracellular microelectrodes. Invest Ophthalmol Vis Sci. 2005;46:1486-1496.
26. Jensen RJ, Ziv OR, Rizzo JF. Responses of rabbit retinal ganglion cells to electrical stimulation with an epiretinal electrode. J Neur Eng. 2005;2:S16-S21.
27. de Balthasar C, Patel S, Roy A, et al. Factors affecting perceptual thresholds in epiretinal prostheses. Invest Ophthalmol Vis Sci. 2008;49:2303-2314.
28. Wichmann FA, Hill NJ. The psychometric function: II. Bootstrap-based confidence intervals and sampling. Percept Psychophys. 2001;63:1314-1329.
29. de Balthasar C, Patel S, Roy A, et al. Factors affecting perceptual thresholds in retinal prostheses. Invest Ophthalmol Vis Sci. 2008; 49(6):2303-2314.
30. Shannon RV. A model of threshold for pulsatile electrical stimulation of cochlear implants. Hear Res. 1989;40:197-204.
31. Chander D, Chichilnisky EJ. Adaptation to temporal contrast in primate and salamander retina. J Neurosci. 2001;21:9904-9916.
32. Rieke F. Temporal contrast adaptation in salamander bipolar cells. J Neurosci. 2001;21:9445-9454.
33. Baccus SA, Meister M. Fast and slow contrast adaptation in retinal circuitry. Neuron. 2002;36:909-919.
34. Watson AB. Temporal sensitivity. In: Boff K, Kaufman L, Thomas J, eds. Handbook of Perception and Human Performance. New York: Wiley; 1986:6.1-6.43.
35. Heijl A, Lindgren G, Olsson J. Normal variability of static perimetric threshold values across the central visual field. Arch Ophthalmol. 1987;105:1544-1549.
36. Katz J, Sommer A. A longitudinal study of the age-adjusted variability of automated visual fields. Arch Ophthalmol. 1987;105: 1083-1086.
37. Foley J, Boynton G. A new model of human luminance pattern vision mechanisms: analysis of the effects of pattern orientation, spatial phase, and temporal frequency. In: Lawton T, ed. Computational Vision Based on Neurobiology. Bellingham, WA: SPIE Proceedings; 1994:12-31.
38. Fried SI, Hsueh HA, Werblin FS. A method for generating precise temporal patterns of retinal spiking using prosthetic stimulation. J Neurophysiol. 2006;95:970-978.
39. Foley JM. Human luminance pattern-vision mechanisms: masking experiments require a new model. J Opt Soc Am A. 1994;11:1710-1719.
40. Brummer SB, Turner MJ. Electrical stimulation of the nervous system: the principle of safe charge injection with Noble metal electrodes. Bioelectrochem Bioenerget. 1975;2:13.
41. Brummer SB, Robblee LS, Hambrecht FT. Criteria for selecting electrodes for electrical stimulation: theoretical and practical considerations. Ann N Y Acad Sci. 1983;405:159-171.
42. McCreery DB, Agnew WF, Yuen TG, Bullara LA. Comparison of neural damage induced by electrical stimulation with faradaic and capacitor electrodes. Ann Biomed Eng. 1988;16:463.
43. McCreery DB, Agnew WF, Agnew WF, McCreery DB. Mechanisms of Stimulation-Induced Neural Damage and Their Relation to Guidelines for Safe Stimulation: Neural Prostheses Fundamental Studies. Englewood Cliffs, NJ: Prentice Hall; 1990:297.
44. Shannon RV. A model of safe levels for electrical stimulation. IEEE Trans Biomed Eng. 1992;39:424-426.
45. Graham CH. Vision and Visual Perception. New York: John Wiley and Sons, Inc.; 1965:637.
46. Dagnelie G. Temporal impulse responses from flicker sensitivities: practical considerations. J Opt Soc Am A. 1992;9:659-672.
47. Felius J, Swanson WH. Photopic temporal processing in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1999;40:2932-2944.
48. Shady S, MacLeod DI, Fisher HS. Adaptation from invisible flicker. Proc Natl Acad Sci U S A. 2004;101:5170-5173.
49. Sekirnjak C, Hottowy P, Sher A, Dabrowski W, Litke AM, Chichilnisky EJ. Electrical stimulation of mammalian retinal ganglion cells with multielectrode arrays. J Neurophysiol. 2006;95:3311-3327.
50. Hecht S, Shlaer S, Pirenne MH. Energy at the threshold of vision. Science. 1942;93:585-587.
51. Campbell FW, Robson JG. Application of Fourier analysis to the visibility of gratings. J Physiol (Lond). 1968;197:551-566.
52. Henning GB, Hertz BG, Broadbent DE. Some experiments bearing on the hypothesis that the visual system analyses spatial patterns in independent bands of spatial frequency. Vision Res. 1975;15:887-897.
53. Albrecht DG, De Valois RL. Striate cortex responses to periodic patterns with and without the fundamental harmonics. J Physiol. 1981;319:497-514.
54. Mandler MB, Makous W. A three channel model of temporal frequency perception. Vision Res. 1984;24:1881-1887.
55. Strettoi E, Pignatelli V, Rossi C, Porciatti V, Falsini B. Remodeling of second-order neurons in the retina of rd/rd mutant mice. Vision Res. 2003;43:867-877.
56. Marc RE, Jones BW, Anderson JR, et al. Neural reprogramming in retinal degeneration. Invest Ophthalmol Vis Sci. 2007;48:3364-3371.
57. Stasheff SF. Emergence of sustained spontaneous hyperactivity and temporary preservation of OFF responses in ganglion cells of the retinal degeneration (rd1) mouse. J Neurophysiol. 2008;99(3): 1408-1421.
58. O'Brien BJ, Isayama T, Richardson R, Berson DM. Intrinsic physiological properties of cat retinal ganglion cells. J Physiol. 2002; 538:787-802.
59. Lipton SA, Tauck DL. Voltage-dependent conductances of solitary ganglion cells dissociated from the rat retina. J Physiol. 1987;385: 361-391.
60. Greenberg RJ. Analysis of Electrical Stimulation of the Vertebrate Retina: Work Towards a Retinal Prosthesis. Baltimore: Johns Hopkins University; 1998.
61. Reid RC, Victor JD, Shapley RM. Broadband temporal stimuli decrease the integration time of neurons in cat striate cortex. Vis Neurosci. 1992;9:39-45.
62. Marc RE, Jones BW, Watt CB, Strettoi E. Neural remodeling in retinal degeneration. Prog Retin Eye Res. 2003;22:607-655.