A Fused Silica Micro-Electrospray Tip with an Electrically Floating Metal Wire Insert to Achieve More Stable Electrospray Ionization

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 5, 2009, Pages 751-754

  Chung, YunJo ^a   Park, ChungUng ^a   Kwon, Joseph ^a,b   Kim, Sunghwan ^c  

^a Chonbuk National University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AIR BUBBLES; ELECTRIC CONDUCTIONS; ELECTROSPRAY PROCESS; ELECTROSPRAY TIPS; FUSED-SILICA CAPILLARIES; METAL WIRES; SIGNAL DETERIORATIONS; SIGNAL STABILITIES; SPRAY CURRENTS; SPRAY TIPS;

ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDES; SILICA; WIRE;

FUSED SILICA;

SILICON DIOXIDE;

ARTICLE; CHEMICAL COMPOSITION; ELECTRIC CONDUCTIVITY; ELECTRIC POTENTIAL; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ANIMALS; EQUIPMENT DESIGN; PEPTIDE FRAGMENTS; PHOSPHORYLASE B; RABBITS; SILICON DIOXIDE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPSIN;

EID: 64049091372     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.12.009     Document Type: Article

References (23)

1. Yamashita M., and Fenn J.B. Electrospray Ion-Source-Another Variation on the Free-Jet Theme. J. Phys. Chem. 88 (1984) 4451-4459
2. Fenn J.B., Mann M., Meng C.K., Wong S.F., and Whitehouse C.M. Electrospray Ionization for Mass-Spectrometry of Large Biomolecules. Science. 246 (1989) 64-71
3. Aebersold R., and Mann M. Mass Spectrometry-Based Proteomics. Nature 422 (2003) 198-207
4. Kim S., Kramer R.W., and Hatcher P.G. Graphical Method for Analysis of Ultrahigh-Resolution Broadband Mass Spectra of Natural Organic Matter, the Van Krevelen Diagram. Anal. Chem. 75 (2003) 5336-5344
5. Kim S.W., Kaplan L.A., Benner R., and Hatcher P.G. Hydrogen-Deficient Molecules in Natural Riverine Water Samples-Evidence for the Existence of Black Carbon in DOM. Mar. Chem. 92 (2004) 225-234
6. Marshall A.G., and Rodgers R.P. Petroleomics: The Next Grand Challenge for Chemical Analysis. Acc. Chem. Res. 37 (2004) 53-59
7. Rodgers R.P., Schaub T.M., and Marshall A.G. Petroleomics: MS Returns to Its Roots. Anal. Chem. 77 (2005) 20A-27A
8. Emmett M.R., White F.M., Hendrickson C.L., Shi S.D.H., and Marshall A.G. Application of Micro-Electrospray Liquid Chromatography Techniques to FT-ICR MS to Enable High-Sensitivity Biological Analysis. J. Am. Soc. Mass Spectrom. 9 (1998) 333-340
9. Emmett M.R., and Caprioli R.M. Micro-Electrospray MS: Ultra-High-Sensitivity Analysis of Peptides and Proteins. J. Am. Soc. Mass Spectrom. 5 (1994) 605-613
10. Hannis J.C., and Muddiman D.C. Nanoelectrospray Mass Spectrometry Using Nonmetalized, Tapered (50 → 10 μM) Fused-Silica Capillaries. Rapid Commun. Mass Spectrom. 12 (1998) 443-448
11. Ishihama Y., Katayama H., Asakawa N., and Oda Y. Highly Robust Stainless Steel Tips as Micro Electro Spray Emitters. Rapid Commun. Mass Spectrom. 16 (2002) 913-918
12. Wilm M., and Mann M. Analytical Properties of the Nanoelectrospray Ion Source. Anal. Chem. 68 (1996) 1-8
13. Valaskovic G.A., and McLafferty F.W. Long-Lived Metallized Tips for Nanoliter Electrospray Mass Spectrometry. J. Am. Soc. Mass Spectrom. 7 (1996) 1270-1272
14. Chang Y.Z., and Her G.R. Sheathless Capillary Electrophoresis/Electrospray Mass Spectrometry Using a Carbon-Coated Fused Silica Capillary. Anal. Chem. 72 (2000) 626-630
15. Nilsson S., Wetterhall M., Bergquist J., Nyholm L., and Markides K.E. A Simple and Robust Conductive Graphite Coating for Sheathless Electrospray Emitters Used in Capillary Electrophoresis/Mass Spectrometry. Rapid Commun. Mass Spectrom. 15 (2001) 1997-2000
16. Sen A.K., Darabi J., and Knapp D.R. Simulation and Parametric Study of a Novel Multi-Spray Emitter for ESI-MS Applications. J. Microfluidics Nanofluidics 3 (2007) 283-298
17. Maziarz E.P., Lorenz S.A., White T.P., and Wood T.D. Polyaniline: A Conductive Polymer Coating for Durable Nanospray Emitters. J. Am. Soc. Mass Spectrom. 11 (2000) 659-663
18. Jackson G.S., and Enke C.G. Electrical Equivalence of Electrospray Ionization with Conducting and Nonconducting Needles. Anal. Chem. 71 (1999) 3777-3784
19. Kriger M.S., Cook K.D., and Ramsey R.S. Durable Gold-Coated Fused-Silica Capillaries for Use in Electrospray Mass-Spectrometry. Anal. Chem. 67 (1995) 385-389
20. Valaskovic G.A., Kelleher N.L., Little D.P., Aaserud D.J., and McLafferty F.W. Attomole-Sensitivity Electrospray Source for Large-Molecule Mass-Spectrometry. Anal. Chem. 67 (1995) 3802-3805
21. Fang L.L., Zhang R., Williams E.R., and Zare R.N. Online Time-of-Flight Mass-Spectrometric Analysis of Peptides Separated by Capillary Electrophoresis. Anal. Chem. 66 (1994) 3696-3701
22. Fong K.W.Y., and Chan T.W.D. A Novel Nonmetallized Tip for Electrospray Mass Spectrometry at Nanoliter Flow Rate. J. Am. Soc. Mass Spectrom. 10 (1999) 72-75
23. Van Berkel G.J., Asano K.G., and Schnier P.D. Electrochemical Processes in a Wire-in-a-Capillary Bulk-Loaded, Nano-Electrospray Emitter. J. Am. Soc. Mass Spectrom. 12 (2001) 853-862