Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

Blood

Volumn 113, Issue 10, 2009, Pages 2298-2301

  O'Shea, Derville ^a   O'Riain, Ciaran ^a   Gupta, Manu ^a   Waters, Rachel ^b   Yang, Youwen ^a   Wrench, David ^a   Gribben, John ^a   Rosenwald, Andreas ^c   Ott, German ^c,d   Rimsza, Lisa M ^e   Holte, Harald ^f   Cazier, Jean Baptiste ^a,g   Johnson, Nathalie A ^h   Campo, Elias ⁱ   Chan, Wing C ^j   Gascoyne, Randy D ^a   Young, Bryan D ^a   Staudt, Louis M ^k   Lister, T Andrew ^a   Fitzgibbon, Jude ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d ROBERT BOSCH HOSPITAL   (Germany)

^e UNIVERSITY OF ARIZONA   (United States)

^f OSLO UNIVERSITY HOSPITAL   (Norway)

^g IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^h BRITISH COLUMBIA CANCER AGENCY   (Canada)

ⁱ UNIVERSITY OF BARCELONA   (Spain)

^j UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^k NATIONAL CANCER INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CANCER RISK; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FOLLICULAR LYMPHOMA; GENE IDENTIFICATION; GENE NUMBER; GENETIC ANALYSIS; HUMAN; LYMPHOCYTE TRANSFORMATION; MAJOR CLINICAL STUDY; MITOTIC RECOMBINATION; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; SINGLE NUCLEOTIDE POLYMORPHISM; UNIPARENTAL DISOMY;

EID: 64049088845     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-08-174953     Document Type: Article

References (24)

1. Gallagher CJ, Gregory WM, Jones AE, et al. Follicular lymphoma: prognostic factors for response and survival. J Clin Oncol. 1986;4:1470-1480.
2. Fisher RI, LeBlanc M, Press OW, Maloney DG, Unger JM, Miller TP. New treatment options have changed the survival of patients with follicular lymphoma. J Clin Oncol. 2005;23:8447-8452.
3. Liu Q, Fayad L, Cabanillas F, et al. Improvement of overall and failure-free survival in stage IV fol-licular lymphoma: 25 years of treatment experience at The University of Texas M.D. Anderson Cancer Center. J Clin Oncol. 2006;24:1582-1589.
4. Bastion Y, Sebban C, Berger F, et al. Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients. J Clin Oncol. 1997;15:1587-1594.
5. Montoto S, Davies AJ, Matthews J, et al. Risk and clinical implications of transformation of follicular lymphoma to diffuse large B-cell lymphoma. J Clin Oncol. 2007;25:2426-2433.
6. Hoglund M, Sehn L, Connors JM, et al. Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lympho-mas. Genes Chromosomes Cancer. 2004;39:195-204.
7. Horsman DE, Connors JM, Pantzar T, Gascoyne RD. Analysis of secondary chromosomal alterations in 165 cases of follicular lymphoma with t(14;18). Genes Chromosomes Cancer. 2001;30: 375-382.
8. Tilly H, Rossi A, Stamatoullas A, et al. Prognostic value of chromosomal abnormalities in follicular lymphoma. Blood. 1994;84:1043-1049.
9. Viardot A, Moller P, Hogel J, et al. Clinicopatho-logic correlations of genomic gains and losses in follicular lymphoma. J Clin Oncol. 2002;20:4523-4530.
10. Raghavan M, Lillington DM, Skoulakis S, et al. Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental dis-omy due to somatic recombination in acute my-eloid leukemias. Cancer Res. 2005;65:375-378.
11. Walker BA, Leone PE, Jenner MW, et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. Blood. 2006;108:1733-1743.
12. Fitzgibbon J, Iqbal S, Davies A, et al. Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma. Leukemia. 2007;21:1514-1520.
13. Ross CW, Ouillette PD, Saddler CM, Shedden KA, Malek SN. Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis. Clin Cancer Res. 2007;13:4777-4785.
14. Matsuzaki H, Loi H, Dong S, et al. Parallel geno-typing of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array. Genome Res. 2004;14:414-425.
15. Gupta M, Raghavan M, Gale RE, et al. Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia. Genes Chromosomes Cancer. 2008.
16. Kemp Z, Carvajal-Carmona L, Spain S, et al. Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan. Hum Mol Genet. 2006;15:2903-2910.
17. Neri A, Fracchiolla NS, Migliazza A, Trecca D, Lombardi L. The involvement of the candidate proto-oncogene NFKB2/lyt-10 in lymphoid malignancies. Leuk Lymphoma. 1996;23:43-48.
18. Dave SS, Wright G, Tan B, et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med. 2004;351:2159-2169.
19. Schwaenen C, Viardot A, Berger H, et al. Microar-ray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status. Genes Chromosomes Cancer. 2009;48:39-54.
20. Cheung KJ, Shah SP, Steidl C, et al. Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prog-nostically significant DNAcopy number imbalances. Blood. 2009;113:137-148.
21. Viardot A, Barth TF, Moller P, Dohner H, Bentz M. Cytogenetic evolution of follicular lymphoma. Se-min Cancer Biol. 2003;13:183-190.
22. Milani L, Gupta M, Andersen M, et al. Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells. Nucleic Acids Res. 2007;35:e34.
23. Gondek LP, Tiu R, O'Keefe CL, Sekeres MA, Theil KS, Maciejewski JP. Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood.2008;111:1534-1542.
24. O'Keefe CL, Gondek LP, Tiu R, et al. Identification of chromosomal abnormalities in healthy bone marrow using 250K SNP arrays[abstract].Blood. 2006;108:Abstract 2076. 2302-2311