Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: Regulation by pertussis toxin-sensitive G i protein and cAMP

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 3, 2009, Pages

  Hilal Dandan, Randa ^a,b   He, Huaping ^a   Martin, Jody L ^a   Brunton, Laurence L ^a   Dillmann, Wolfgang H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

Author keywords

G i; G q; Hypertrophy; Sarcoplasmic reticulum calcium ATPase

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; BUCLADESINE; CYCLIC AMP; ENDOTHELIN; ENDOTHELIN A RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITIDE; PHOSPHODIESTERASE INHIBITOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; UNCLASSIFIED DRUG; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; 4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; ATP2A2 PROTEIN, RAT; CYCLIC CMP; DIBUTYRYL CYCLIC 3',5' CYTIDINE MONOPHOSPHATE; DIBUTYRYL CYCLIC-3',5'-CYTIDINE MONOPHOSPHATE; DRUG DERIVATIVE; ENDOTHELIN 1; ESTRANE DERIVATIVE; GNAI1 PROTEIN, RAT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHOLIPASE C;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HEART MUSCLE CELL; HYDROLYSIS; INHIBITION KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; RECEPTOR BINDING; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEART VENTRICLE; METABOLISM; MUTATION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TIME;

4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC CMP; DOWN-REGULATION; ENDOTHELIN-1; ESTRENES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEART VENTRICLES; MALE; MUTATION; MYOCYTES, CARDIAC; PERTUSSIS TOXIN; PHOSPHODIESTERASE INHIBITORS; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RNA, MESSENGER; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TYPE C PHOSPHOLIPASES;

EID: 64049087677     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00584.2008     Document Type: Article

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