-
1
-
-
0344082608
-
Progress in the development and acquisition of anticancer agents from marine sources
-
ML Amador J Jimeno L Paz-Ares H Cortes-Funes M Hidalgo 2003 Progress in the development and acquisition of anticancer agents from marine sources Ann Oncol 14 1607 1615
-
(2003)
Ann Oncol
, vol.14
, pp. 1607-1615
-
-
Amador, M.L.1
Jimeno, J.2
Paz-Ares, L.3
Cortes-Funes, H.4
Hidalgo, M.5
-
2
-
-
33750445585
-
Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype
-
JH Beumer T Buckle M Ouwehand NE Franke L Lopez-Lazaro JH Schellens JH Beijnen O van Tellingen 2007 Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype Invest New Drugs 25 1 7
-
(2007)
Invest New Drugs
, vol.25
, pp. 1-7
-
-
Beumer, J.H.1
Buckle, T.2
Ouwehand, M.3
Franke, N.E.4
Lopez-Lazaro, L.5
Schellens, J.H.6
Beijnen, J.H.7
Van Tellingen, O.8
-
3
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
-
J Carmichael WG DeGraff AF Gazdar JD Minna JB Mitchell 1987 Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing Cancer Res 47 936 942
-
(1987)
Cancer Res
, vol.47
, pp. 936-942
-
-
Carmichael, J.1
Degraff, W.G.2
Gazdar, A.F.3
Minna, J.D.4
Mitchell, J.B.5
-
4
-
-
35048860778
-
Trabectedin: A review of its use in the management of soft tissue sarcoma and ovarian cancer
-
NJ Carter SJ Keam 2007 Trabectedin: a review of its use in the management of soft tissue sarcoma and ovarian cancer Drugs 67 2257 2276
-
(2007)
Drugs
, vol.67
, pp. 2257-2276
-
-
Carter, N.J.1
Keam, S.J.2
-
6
-
-
0035874074
-
Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways
-
G Damia S Silvestri L Carrassa L Filiberti GT Faircloth G Liberi M Foiani M D'Incalci 2001 Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways Int J Cancer 92 583 588
-
(2001)
Int J Cancer
, vol.92
, pp. 583-588
-
-
Damia, G.1
Silvestri, S.2
Carrassa, L.3
Filiberti, L.4
Faircloth, G.T.5
Liberi, G.6
Foiani, M.7
D'Incalci, M.8
-
9
-
-
0034099849
-
Isolation and characterization of an IGROV-1 human ovarian cancer cell line made resistant to Ecteinascidin-743 (ET-743)
-
E Erba D Bergamaschi L Bassano S Ronzoni G Di Liberti I Muradore S Vignati G Faircloth J Jimeno M D'Incalci 2000 Isolation and characterization of an IGROV-1 human ovarian cancer cell line made resistant to Ecteinascidin-743 (ET-743) Br J Cancer 82 1732 1739
-
(2000)
Br J Cancer
, vol.82
, pp. 1732-1739
-
-
Erba, E.1
Bergamaschi, D.2
Bassano, L.3
Ronzoni, S.4
Di Liberti, G.5
Muradore, I.6
Vignati, S.7
Faircloth, G.8
Jimeno, J.9
D'Incalci, M.10
-
10
-
-
39049178652
-
Kahalalide F and ES285: Potent anticancer agents from marine molluscs
-
G Faircloth C Cuevas 2006 Kahalalide F and ES285: potent anticancer agents from marine molluscs Prog Mol Subcell Biol 43 363 379
-
(2006)
Prog Mol Subcell Biol
, vol.43
, pp. 363-379
-
-
Faircloth, G.1
Cuevas, C.2
-
11
-
-
0029074372
-
ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): No inhibition by intracellular glutathione depletion
-
N Feller HJ Broxterman DC Wahrer HM Pinedo 1995 ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion FEBS Lett 368 385 388
-
(1995)
FEBS Lett
, vol.368
, pp. 385-388
-
-
Feller, N.1
Broxterman, H.J.2
Wahrer, D.C.3
Pinedo, H.M.4
-
12
-
-
24944460785
-
Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: Multicenter phase II and pharmacokinetic study
-
R Garcia-Carbonero JG Supko RG Maki J Manola DP Ryan D Harmon TA Puchalski G Goss MV Seiden A Waxman MT Quigley T Lopez MA Sancho J Jimeno C Guzman GD Demetri 2005 Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study J Clin Oncol 23 5484 5492
-
(2005)
J Clin Oncol
, vol.23
, pp. 5484-5492
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Maki, R.G.3
Manola, J.4
Ryan, D.P.5
Harmon, D.6
Puchalski, T.A.7
Goss, G.8
Seiden, M.V.9
Waxman, A.10
Quigley, M.T.11
Lopez, T.12
Sancho, M.A.13
Jimeno, J.14
Guzman, C.15
Demetri, G.D.16
-
13
-
-
0037096747
-
Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a phase II trial
-
ML Hensley R Maki E Venkatraman G Geller M Lovegren C Aghajanian P Sabbatini W Tong R Barakat DR Spriggs 2002 Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a phase II trial J Clin Oncol 20 2824 2831
-
(2002)
J Clin Oncol
, vol.20
, pp. 2824-2831
-
-
Hensley, M.L.1
Maki, R.2
Venkatraman, E.3
Geller, G.4
Lovegren, M.5
Aghajanian, C.6
Sabbatini, P.7
Tong, W.8
Barakat, R.9
Spriggs, D.R.10
-
14
-
-
33748035692
-
Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin
-
AB Herrero C Martin-Castellanos E Marco F Gago S Moreno 2006 Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin Cancer Res 66 8155 8162
-
(2006)
Cancer Res
, vol.66
, pp. 8155-8162
-
-
Herrero, A.B.1
Martin-Castellanos, C.2
Marco, E.3
Gago, F.4
Moreno, S.5
-
16
-
-
37049038819
-
A Phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum-based regimens
-
CN Krasner DS McMeekin S Chan PS Braly FG Renshaw S Kaye DM Provencher S Campos ME Gore 2007 A Phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum-based regimens Br J Cancer 97 1618 1624
-
(2007)
Br J Cancer
, vol.97
, pp. 1618-1624
-
-
Krasner, C.N.1
McMeekin, D.S.2
Chan, S.3
Braly, P.S.4
Renshaw, F.G.5
Kaye, S.6
Provencher, D.M.7
Campos, S.8
Gore, M.E.9
-
17
-
-
20044372153
-
Phase II study of ET-743 in advanced soft tissue sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
-
A Le Cesne JY Blay I Judson A Van Oosterom J Verweij J Radford P Lorigan S Rodenhuis I Ray-Coquard S Bonvalot F Collin J Jimeno E Di Paola M Van Glabbeke OS Nielsen 2005 Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial J Clin Oncol 23 576 584
-
(2005)
J Clin Oncol
, vol.23
, pp. 576-584
-
-
Le Cesne, A.1
Blay, J.Y.2
Judson, I.3
Van Oosterom, A.4
Verweij, J.5
Radford, J.6
Lorigan, P.7
Rodenhuis, S.8
Ray-Coquard, I.9
Bonvalot, S.10
Collin, F.11
Jimeno, J.12
Di Paola, E.13
Van Glabbeke, M.14
Nielsen, O.S.15
-
18
-
-
33845713308
-
Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of clusterin/apolipoprotein
-
M Lourda IP Trougakos ES Gonos 2007 Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of clusterin/apolipoprotein J Int J Cancer 120 611 622
-
(2007)
J Int J Cancer
, vol.120
, pp. 611-622
-
-
Lourda, M.1
Trougakos, I.P.2
Gonos, E.S.3
-
19
-
-
33644816649
-
The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71
-
MC Manara S Perdichizzi M Serra R Pierini S Benini CM Hattinger A Astolfi R Bagnati M D'Incalci P Picci K Scotlandi 2005 The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71 Int J Oncol 27 1605 1616
-
(2005)
Int J Oncol
, vol.27
, pp. 1605-1616
-
-
Manara, M.C.1
Perdichizzi, S.2
Serra, M.3
Pierini, R.4
Benini, S.5
Hattinger, C.M.6
Astolfi, A.7
Bagnati, R.8
D'Incalci, M.9
Picci, P.10
Scotlandi, K.11
-
20
-
-
0033981511
-
Antitumor compounds from tunicates
-
KL Rinehart 2000 Antitumor compounds from tunicates Med Res Rev 20 1 27
-
(2000)
Med Res Rev
, vol.20
, pp. 1-27
-
-
Rinehart, K.L.1
-
21
-
-
0025131974
-
Bioactive compounds from aquatic and terrestrial sources
-
KL Rinehart TG Holt NL Fregeau PA Keifer GR Wilson TJ Perun Jr R Sakai AG Thompson JG Stroh LS Shield 1990 Bioactive compounds from aquatic and terrestrial sources J Nat Prod 53 771 792
-
(1990)
J Nat Prod
, vol.53
, pp. 771-792
-
-
Rinehart, K.L.1
Holt, T.G.2
Fregeau, N.L.3
Keifer, P.A.4
Wilson, G.R.5
Perun Jr, T.J.6
Sakai, R.7
Thompson, A.G.8
Stroh, J.G.9
Shield, L.S.10
-
22
-
-
0033518874
-
Atypical multidrug resistance: Breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines
-
DD Ross W Yang LV Abruzzo WS Dalton E Schneider H Lage M Dietel L Greenberger SP Cole LA Doyle 1999 Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines J Natl Cancer Inst 91 429 433
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 429-433
-
-
Ross, D.D.1
Yang, W.2
Abruzzo, L.V.3
Dalton, W.S.4
Schneider, E.5
Lage, H.6
Dietel, M.7
Greenberger, L.8
Cole, S.P.9
Doyle, L.A.10
-
23
-
-
34547867058
-
Trabectedin (ET-743): Evaluation of its use in advanced soft-tissue sarcoma
-
P Schoffski P Wolter P Clement R Sciot I De Wever A Wozniak C Stefan H Dumez 2007 Trabectedin (ET-743): evaluation of its use in advanced soft-tissue sarcoma Future Oncol 3 381 392
-
(2007)
Future Oncol
, vol.3
, pp. 381-392
-
-
Schoffski, P.1
Wolter, P.2
Clement, P.3
Sciot, R.4
De Wever, I.5
Wozniak, A.6
Stefan, C.7
Dumez, H.8
-
24
-
-
1242339608
-
Targeted therapy for epithelial ovarian cancer: Current status and future prospects
-
HT See JJ Kavanagh W Hu RC Bast 2003 Targeted therapy for epithelial ovarian cancer: current status and future prospects Int J Gynecol Cancer 13 701 734
-
(2003)
Int J Gynecol Cancer
, vol.13
, pp. 701-734
-
-
See, H.T.1
Kavanagh, J.J.2
Hu, W.3
Bast, R.C.4
-
26
-
-
34548706418
-
Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
-
DG Soares AE Escargueil V Poindessous A Sarasin A de Gramont D Bonatto JA Henriques AK Larsen 2007 Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743 Proc Natl Acad Sci USA 104 13062 13067
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13062-13067
-
-
Soares, D.G.1
Escargueil, A.E.2
Poindessous, V.3
Sarasin, A.4
De Gramont, A.5
Bonatto, D.6
Henriques, J.A.7
Larsen, A.K.8
-
27
-
-
0031848159
-
Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts
-
G Valoti MI Nicoletti A Pellegrino J Jimeno H Hendriks M D'Incalci G Faircloth R Giavazzi 1998 Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts Clin Cancer Res 4 1977 1983
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1977-1983
-
-
Valoti, G.1
Nicoletti, M.I.2
Pellegrino, A.3
Jimeno, J.4
Hendriks, H.5
D'Incalci, M.6
Faircloth, G.7
Giavazzi, R.8
-
28
-
-
14744306773
-
Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM00104, a novel antineoplastic agent, in mouse, rat, dog, and human plasma
-
J Yin P Aviles W Lee C Ly MJ Guillen S Munt C Cuevas G Faircloth 2005 Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM00104, a novel antineoplastic agent, in mouse, rat, dog, and human plasma Rapid Commun Mass Spectrom 19 689 695
-
(2005)
Rapid Commun Mass Spectrom
, vol.19
, pp. 689-695
-
-
Yin, J.1
Aviles, P.2
Lee, W.3
Ly, C.4
Guillen, M.J.5
Munt, S.6
Cuevas, C.7
Faircloth, G.8
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