Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo

Molecular Biology Reports

Volumn 36, Issue 5, 2009, Pages 1119-1127

  Sun, Zhe ^a   Zhao, Zhenhuan ^a   Zhao, Shiguang ^a   Sheng, Yi ^a   Zhao, Zonghang ^b   Gao, Cheng ^a   Li, Jingwen ^a   Liu, Xiangzhen ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Aquaporin; Autologous whole blood; Recombinant hirudin; Thrombin

Indexed keywords

AQUAPORIN 4; AQUAPORIN 9; BETA ACTIN; H0393; MESSENGER RNA; RECOMBINANT HIRUDIN; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN WATER; CAUDATE NUCLEUS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; IN VIVO STUDY; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; AQUAPORIN 4; AQUAPORINS; BRAIN EDEMA; CEREBRAL HEMORRHAGE; GENE EXPRESSION REGULATION; HIRUDINS; MAGNETIC RESONANCE IMAGING; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; RNA, MESSENGER;

RATTUS;

EID: 63949086489     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-008-9287-3     Document Type: Article

References (39)

1. KR Lee GP Colon AL Betz 1996 Edema from intracerebral hemorrhage: the role of thrombin J Neurosurg 84 1 91 96
2. G Xi KR Wagner RF Keep 1998 Role of blood clot formation on early edema development following experimental intracerebral hemorrhage Stroke 29 12 2580 2586
3. C Loret M Sensenbrenner G Labourdette 1989 Differential phenotypic expression induced in cultured rat astroblasts by acidic fibroblast growth factor, epidermal growth factor, and thrombin J Biol Chem 264 14 8319 8327
4. D Gurwitz DD Cunningham 1988 Thrombin modulates and reverses neuroblastoma neurite outgrowth Proc Natl Acad Sci USA 85 10 3440 3444 10.1073/pnas.85.10.3440
5. KR Lee AL Betz RF Keep 1995 Intracerebral infusion of thrombin as a cause of brain edema J Neurosurg 83 6 1045 1050
6. KR Lee AL Betz S Kim 1996 The role of the coagulation cascade in brain edema formation after intracerebral hemorrhage Acta Neurochir (Wien) 138 4 396 401 10.1007/BF01420301
7. JL Venero ML Vizuete A Machado 2001 Aquaporins in the central nervous system Prog Neurobiol 63 3 321 336 10.1016/S0301-0082(00)00035-6
8. J Badaut JM Petit JF Brunet 2004 Distribution of aquaporin 9 in the adult rat brain: preferential expression in catecholaminergic neurons and in glial cells Neuroscience 128 1 27 38 10.1016/j.neuroscience.2004.05.042
9. JS Jung RV Bhat GM Preston 1994 Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance Proc Natl Acad Sci USA 91 26 13052 13056 10.1073/pnas.91.26.13052
10. JL Venero ML Vizuete AA Ilundain 1999 Detailed localization of aquaporin-4 messenger RNA in the CNS: preferential expression in periventricular organs Neuroscience 94 1 239 250 10.1016/S0306-4522(99)00182-7
11. Y Hiroaki K Tani A Kamegawa 2006 Implications of the aquaporin-4 structure on array formation and cell adhesion J Mol Biol 355 4 628 639 10.1016/j.jmb.2005.10.081
12. S Nielsen EA Nagelhus M Amiry-Moghaddam 1997 Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain J Neurosci 17 1 171 180
13. M de Castro Ribeiro L Hirt J Bogousslavsky 2006 Time course of aquaporin expression after transient focal cerebral ischemia in mice J Neurosci Res 83 7 1231 1240 10.1002/jnr.20819
14. K Ishibashi M Kuwahara Y Gu 1998 Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol Biochem Biophys Res Commun 244 1 268 274 10.1006/bbrc.1998.8252
15. H Tsukaguchi C Shayakul UV Berger 1998 Molecular characterization of a broad selectivity neutral solute channel J Biol Chem 273 38 24737 24743 10.1074/jbc.273.38.24737
16. M Amiry-Moghaddam H Lindland S Zelenin 2005 Brain mitochondria contain aquaporin water channels: evidence for the expression of a short AQP9 isoform in the inner mitochondrial membrane FASEB J 19 11 1459 1467 10.1096/fj.04-3515com
17. R Hamada H Matsuoka 2000 Antithrombin therapy for intracerebral hemorrhage Stroke 31 3 791 795
18. F Markwardt 1994 The development of hirudin as an antithrombotic drug Thromb Res 74 1 1 23 10.1016/0049-3848(94)90032-9
19. A Koster H Kuppe R Hetzer 1998 Emergent cardiopulmonary bypass in five patients with heparin-induced thrombocytopenia type II employing recombinant hirudin Anesthesiology 89 3 777 780 10.1097/00000542-199809000-00029
20. N Lubenow P Eichler T Lietz 2004 Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies Blood 104 10 3072 3077 10.1182/blood-2004-02-0621
21. SR Mehta JW Eikelboom HJ Rupprecht 2002 Efficacy of hirudin in reducing cardiovascular events in patients with acute coronary syndrome undergoing early percutaneous coronary intervention Eur Heart J 23 2 117 123 10.1053/euhj.2001. 2731
22. TS Choi AI Khan PE Greilich 2006 Modified plasma-based ecarin clotting time assay for monitoring of recombinant hirudin during cardiac surgery Am J Clin Pathol 125 2 290 295 10.1309/0TDG-8BEC-LWCB-XCDK
23. W Steinbrich W Gross-Fengels GP Krestin 1990 Intracranial hemorrhages in the magnetic resonance tomogram: studies on sensitivity, on the development of hematomas and on the determination of the cause of the hemorrhage Rofo 152 5 534 543
24. TN Lin YY He G Wu 1993 Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats Stroke 24 1 117 121
25. GY Yang AL Betz TL Chenevert 1994 Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in rats J Neurosurg 81 1 93 102
26. GH Xi RF Keep Y Hua 1999 Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning Stroke 30 6 1247 1255
27. H Arima N Yamamoto K Sobue 2003 Hyperosmolar mannitol stimulates expression of aquaporins 4 and 9 through a p38 mitogen-activated protein kinase-dependent pathway in rat astrocytes J Biol Chem 278 45 44525 44534 10.1074/jbc.M304368200
28. AH Koeppen AC Dickson JA McEvoy 1995 The cellular reactions to experimental intracerebral hemorrhage J Neurol Sci 34 suppl 1 102 112 10.1016/0022-510X(95)00215-N
29. M Karabiyikoglu Y Hua RF Keep 2004 Intracerebral hirudin injection attenuates ischemic damage and neurologic deficits without altering local cerebral blood flow J Cereb Blood Flow Metab 24 2 159 166 10.1097/01.WCB. 0000100062.36077.84
30. FM Donovan CJ Pike CW Cotman 1997 Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities Neuroscience 17 14 5316 5326
31. C Ke WS Poon HK Ng 2001 Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats Neurosci Lett 301 1 21 24 10.1016/S0304-3940(01)01589-0
32. KL Kiening FK van Landeghem S Schreiber 2002 Decreased hemispheric aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats Neurosci Lett 324 2 105 108 10.1016/S0304-3940(02)00180-5
33. J Badaut L Hirt C Granziera 2001 Astrocyte-specific expression of aquaporin-9 in mouse brain is increased after transient focal cerebral ischemia J Cereb Blood Flow Metab 21 5 477 482 10.1097/00004647-200105000-00001
34. Y Hua G Xi RF Keep 2000 Complement activation in the brain after experimental intracerebral hemorrhage J Neurosurg 92 6 1016 1022
35. GH Xi Y Hua FK Richard 2001 Systemic complement depletion diminishes perihematomal brain edema in rats Stroke 32 1 162 167 10.1161/hs1201.099820
36. GT Manley M Fujimura T Ma 2000 Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke Nat Med 6 2 159 163 10.1038/72256
37. JE Rash T Yasumura CS Hudson 1998 Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord Proc Natl Acad Sci USA 95 20 11981 11986 10.1073/pnas.95.20.11981
38. MC Papadopoulos GT Manley S Krishna 2004 Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema FASEB J 18 11 1291 1293
39. J Badaut L Regli 2004 Distribution and possible roles of aquaporin 9 in the brain Neuroscience 129 4 971 981 10.1016/j.neuroscience.2004.06.035